Man

J Daniel Carpio Paniagua

Director Ejecutivo-Profesor Asociado

Universidad Austral de Chile

Valdivia, Chile

Líneas de Investigación


Estudio de modelos experimentales y en biopsias renales de distintas enfermedades renales. Estudios de modelos experimentales de neuropatía en animales con diversas enfermedades metabólicas.

Educación

  •  Nefropatología, University of North Carolina at Chapel Hill. Estados Unidos, 2001
  •  Anatomía Patológica, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 1997
  •  Médico Cirujano, UNIVERSIDAD DE CHILE. Chile, 1989
  •  Licenciatura en Medicina, UNIVERSIDAD DE CHILE. Chile, 1986

Experiencia Académica

  •   Profesor Instructor Part Time

    UNIVERSIDAD DE CHILE

    Facultad de Medicina Norte

    Santiago, Chile

    1992 - 1994

  •   Profesor Colaborador Externo Part Time

    UNIVERSIDAD METROPOLITANA DE CIENCIAS DE LA EDUCACION

    Pedagogía

    Santiago, Chile

    1992 - 1993

  •   Profesor Auxiliar Part Time

    UNIVERSIDAD AUSTRAL DE CHILE

    Facultad de Medicina

    Valdivia, Chile

    2002 - 2004

  •   Profesor Asociado Part Time

    UNIVERSIDAD AUSTRAL DE CHILE

    Facultad de Medicina

    Valdivia, Chile

    2004 - A la fecha

  •   Profesor Invitado Other

    UNIVERSIDAD DE LA FRONTERA

    Facultad de Medicina

    Temuco, Chile

    2002 - 2007

Experiencia Profesional

  •   Médico General de Atención Primaria Part Time

    Consultorio Alejandro del Río

    Puente Alto-Santiago, Chile

    1989 - 1990

  •   Médico Legista Tanatólogo Part Time

    Instituto Médico Legal de Santiago

    Saniago, Chile

    1991 - 1994

  •   Instructor de Anatomía Normal Part Time

    Universidad de Chile

    Santiago, Chile

    1992 - 1994

  •   Médico becario Anatomía Patológica Full Time

    Hospital Base Valdivia-Universidad Austral de Chile

    Valdivia, Chile

    1994 - 1997

  •   Anátomo Patólogo Full Time

    Servicio Salud Valdivia-Hospital Base Valdivia

    Valdivia, Chile

    1997 - A la fecha

  •   Profesor Auxiliar Part Time

    Universidad Austral de Chile

    Valdivia, Chile

    2002 - 2004

  •   Profesor Asociado Part Time

    Universidad Austral de Chile

    Valdivia, Chile

    2004 - A la fecha


 

Article (22)

Gremlin, A Potential Urinary Biomarker of Anca-Associated Crescentic Glomerulonephritis.
Hepatocellular damage, proteinuria and autoimmunity: multisystemic disorder or coexistence of diseases?
Hepatocellular damage, proteinuria and autoimmunity=> multisystemic disorder or coexistence of diseases?
Kidney injury in systemic lupus erythematosus=> lack of correlation between clinical and histological data
Lyso-Gb3 activates Notch1 in human podocytes
Proregenerative Microenvironment Triggered by Donor Mesenchymal Stem Cells Preserves Renal Function and Structure in Mice with Severe Diabetes Mellitus
Pre-stimulation of the kallikrein system in cisplatin-induced acute renal injury: An approach to renoprotection
Translational study of the Notch pathway in hypertensive nephropathy
Tubular Overexpression of Gremlin Induces Renal Damage Susceptibility in Mice
Altered expression and localization of insulin receptor in proximal tubule cells from human and rat diabetic kidney
Antihypertensive and renoprotective effect of the kinin pathway activated by potassium in a model of salt sensitivity following overload proteinuria
Podocyte-Specific Overexpression of Wild Type or Mutant Trpc6 in Mice Is Sufficient to Cause Glomerular Disease
[Bariatric surgery in patients with focal segmental glomerulosclerosis secondary to obesity].
Bariatric surgery in patients with focal segmental glomerulosclerosis secondary to obesity
Endovenous Administration of Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells Prevents Renal Failure in Diabetic Mice
Vanishing prostate cancer. Clinical presentation and histological review
Gremlin: A novel mediator of epithelial mesenchymal transition and fibrosis in chronic allograft nephropathy
Systemic administration of multipotent mesenchymal stromal cells reverts hyperglycemia and prevents nephropathy in type I diabetic mice
Expression of gremlin, a bone morphogenetic protein antagonist, in glomerular crescents of pauci-immune glomerulonephritis
Renal angiotensin II up-regulation and myofibroblast activation in human membranous nephropathy
Renal angiotensin II up-regulation and myofibroblast activation in human membranous nephropathy
Thyroid lymphoma. A case report.

Abstract (8)

Studies on the reversion of Kidney damage generated by diabetes
TUBULAR OVEREXPRESSION OF GREMLIN IN TRANSGENIC MICE AGGRAVATES RENAL DAMAGE IN DIABETIC NEPHROPATHY
Sodium tungstate attenuates fibrosis through suppression of transforming growth factor-beta 1/Smad3 in diabetic nephropathy
Sodium tungstate decreases the progression of renal damage through inhibition of fibrosis in diabetic rat kidney
Sodium tungstate modulates inflammation of diabetic nephropathy
Expression of FPBase and PEPCK during the progression of tubular damage in diabetic nephropathy
Expression of glyconeogenic and gluconeogenic enzymes in kidney of long-term induced diabetic rats.
Renal angiotensin II upregulation and myofibroblast activation in human membranous nephropathy.

Proyecto (13)

Sistema de Ultramicrotomía para Microscopia Electrónica de Transmisión, Barrido y Microanálisis para Cs Biológicas, de Materiales, Sociales y Antropológicas
Gremlin: a profibrotic and proinflammatory mediator involved in diabetic nephropathy
EVALUATION OF THE THERAPEUTIC EFFECT OF MESENCHYMAL STEM CELL -ACELULAR DERIVATE- ON DRUG INDUCED STEATOSIS, IN A MODEL OF NORMAL AND IMPAIRED LIVER REGENERATION CAPACITY
Desarrollo de un Kit de Diagnóstico temprano para la Nefropatía Diabética, no invasivo y que permita diferenciar la progresividad de esta enfermedad mediante la utilización de Exosomas Urinarios
SODIUM TUNGSTATE A NEW TREATMENT FOR DIABETIC NEPHROPATHY=> EFFECT OF THIS DRUG IN INFLAMMATION, OXIDATIVE STRESS AND FIBROSIS DURING THE PROGRESSION OF THIS PATHOLOGY.
GREMLIN=> A NOVEL RENAL PRO FIBROTIC BIOMARKER ? ITS ROLE IN HUMAN AND EXPERIMENTAL RENAL PATHOLOGY.
THE ETIOLOGY OF DIABETES AND/OR THE STAGE OF DIABETIC NEPHROPATHY MODIFY THE RENOPROTECTIVE EFFECT OF DONOR MULTIPOTENT MESENCHYMAL STROMAL CELLS?
REGULATION OF KIDNEY GLUCOSE AND GLYCOGEN METABOLISM BY INSULIN AND TUNGSTATE IN LONG TERM DIABETIC AND CONTROL RATS.
FIBROSIS RENAL=> ESTUDIO DE NUEVOS MEDIADORES DE TRANSDIFERENCICION EPITELIO MESENQUIMAL (TEM)
ROL DEL SISTEMA CALICREINA-CININAS EN LA PREVENCION DE LA FIBROSIS RENAL
Renal Pathology center of Excellence Grant
"RELACION DEL SINDROME DIABETICO CON LA EXPRESION Y LOCALIZACION CELULAR DE GLICOGENO SINTASA, FOSFOENOLPIRUVATO CARBOXIQUINASA Y FRUCTOSA-1, 6-BISFOSTASA, ENZIMAS CLAVES EN LA HOMEOSTASIS DE LA GLUCOSA"
ESTUDIO DE LA TRANSDIFERENCIACION TUBULO-EPITELIAL EN ENFERMEDAD RENAL PROGRESIVA. ROL DE LA PROTEINURIA Y ANGIOTENSINA II
26
J Daniel Carpio

Director Ejecutivo-Profesor Asociado

Unidad Microscopía Electrónica

Universidad Austral de Chile

Valdivia, Chile

10
Alejandro Yanez

Full professor

Faculty of Science

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

7
Sergio Mezzano

Catedratico

Medicina

Universidad Austral de Chile

Valdivia, Chile

6
Leopoldo Ardiles

Profesor Titular

Medicina

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

3
Fernando Ezquer

Full Professor

Center for Regenerative Medicine

Universidad del Desarrollo

Santiago, Chile

3
Paulette Conget

FACULTAD DE MEDICINA CLINICA ALEMANA-UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

3
Eduardo Ezquer

Director/Full Professor

Centro de Medicina Regenerativa

UNIVERSIDAD DEL DESARROLLO, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS

Santiago, Chile

3
Claudio Flores

Académico

Medicina

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

2
Rody San Martín

Professor

Sciences Faculty

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

2
Carlos Vio

Profesor

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

1
ARELI CÁRDENAS

Académica e Investigadora

Universidad Bernardo O'Higgins

Santiago, Chile

1
Romina Bertinat

Technician

Farmacología

Universidad de Concepcion

Concepción, Chile

1
INGRID EHRENFELD

FULL PROFESSOR

ANATOMIA; HISTOLOGIA & PATOLOGIA

UNIVERSIDAD AUSTRAL DE CHILE

VALDIVIA, Chile

1
Fabian Pardo

Profesor titular

Escuela de Medicina

Universidad de Valparaiso

San Felipe, Chile

1
Carlos Figueroa

Head

Anatomy, Histology and Pathology

Universidad Austral de Chile

Valdivia, Chile

1
Francisco Westermeier

Universidad de Chile

Santiago, Chile

1
Paola Krall

Profesor Auxiliar

Universidad Austral de Chile

Valdivia, Chile

1
Cristián Carrasco

Director

Anatomía Patológica

HOSPITAL BASE VALDIVIA

Valdivia, Chile