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Nicolás Guillermo Santander Grez

Assistant Professor

Universidad de O'Higgins

Rancagua, Chile

Metabolic regulation of brain angiogenesis

Doctorado en Ciencias Médicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2018
Bioquímico, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2012

Postdoctoral Scholar Full Time

UNIVERSITY OF CALIFORNIA-SAN FRANCISCO

San Francisco, Estados Unidos

2019 - 2021
Postdoctoral Researcher Full Time

Universidad de O´Higgins

Chile

2021 - 2023
Assistant Professor Full Time

Universidad de O´Higgins

Chile

2023 - A la fecha


Bone Marrow-Derived Alk1 Mutant Endothelial Cells and Clonally Expanded Somatic Alk1 Mutant Endothelial Cells Contribute to the Development of Brain Arteriovenous Malformations in Mice Shaligram, Sonali S.; Zhu, Wan; Ma, Li; Luo, Man; Li, Qiang; Weiss, Miriam; Arnold, Thomas; Liang, Rich; do Prado, Leandro; Tang, Chaoliang; et al. Article ISI TRANSLATIONAL STROKE RESEARCH (2021)
Lipoprotein receptor SR-B1 deficiency enhances adipose tissue inflammation and reduces susceptibility to hepatic steatosis during diet-induced obesity in mice Amigo, Ludwig; Carrasco, Gonzalo; Andia, Marcelo E.; Rigotti, Attilio Article ISI BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2021)
A new genetic strategy for targeting microglia in development and disease Keown-Lang, Amber E.; Niu, Abraham; Larpthaveesarp, Amara; Chee, Elin; Gonzalez, Fernando F. Article ISI ELIFE (2020)
Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier Article ISI JOURNAL OF CLINICAL INVESTIGATION (2020)
Ovarian cholesterol efflux: ATP-binding cassette transporters and follicular fluid HDL regulate cholesterol content in mouse oocytes Article SCOPUS Biology of Reproduction (2020)
Impaired alpha V beta 8 and TGF beta signaling lead to microglial dysmaturation and neuromotor dysfunction Arnold, Thomas D.; Lizama, Carlos O.; Cautivo, Kelly M.; Lin, Lucia; Qiu, Haiyan; Huang, Eric J.; Liu, Chang; Mukouyama, Yoh-Suke; Reichardt, Louis F.; Zoyein, Ann C.; et al. Article ISI JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Insulin increases cholesterol uptake, lipid droplet content, and apolipoprotein B secretion in CaCo-2 cells by upregulating SR-BI via a PI3K, AKT, and mTOR-dependent pathway Santander, N Article ISI SCOPUS JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
High density lipoprotein cholesterol and proteome in SR-B1 KO mice: lost in precipitation Birner-Gruenberger, Ruth; Wadsack, Christian; Rigotti, Attilio Article ISI SCOPUS JOURNAL OF TRANSLATIONAL MEDICINE (2018)
Transcriptional profiling of embryos lacking the lipoprotein receptor SR-B1 reveals a regulatory circuit governing a neurodevelopmental or metabolic decision during neural tube closure Lizama, Carlos; Godoy, Alejandro; Rigotti, Attilio Article ISI SCOPUS BMC GENOMICS (2018)
Deficient Vitamin E Uptake During Development Impairs Neural Tube Closure in Mice Lacking Lipoprotein Receptor SR-BI Article ISI SCOPUS SCIENTIFIC REPORTS (2017)
Early Onset Intrauterine Growth Restriction in a Mouse Model of Gestational Hypercholesterolemia and Atherosclerosis Busso, D.; Mascareno, L; Salas, F; Berkowitz L.; Santander, N; Quiroz, A; Amigo, L; Valdés, G; Rigotti, A Article ISI SCOPUS BIOMED RESEARCH INTERNATIONAL (2014)
Developmental abnormalities in mouse embryos lacking the HDL receptor SR-BI Santander NG; Contreras-Duarte, S; Awad, MF; Lizama, C; Passalacqua, I; Rigotti, A; Busso, D. Article ISI SCOPUS Human Molecular Genetics (2013)


IMPAIRED NEURAL TUBE CLOSURE IN MICE LACKING HIGH DENSITY LIPOPROTEIN RECEPTOR SR-BI IS ASSOCIATED WITH DEFICIENT VITAMIN E UPTAKE AND ABERRANT GENE EXPRESSION Abstract ISI ANNALS OF NUTRITION AND METABOLISM (2017)
RNA-SEQ ANALYSIS REVEALS CANDIDATE GENES THAT MAY EXPLAIN NEURAL TUBE DEFECTS IN MOUSE EMBRYOS LACKING SR-BI Abstract ISI PLACENTA (2017)
Insulin regulates SRBI and ABCG8 in a mTOR dependent pathway in CaCo-2 cells Abstract ISI DIABETOLOGIA (2016)


Nutrients and gene expression in development Santander, N BookWhole ISI SCOPUS Principles of Nutrigenetics and Nutrigenomics: Fundamentals of Individualized Nutrition (2019)

1

MARCO ARRESE

FULL PROFESSOR

GASTROENTEROLOGY

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

6

Attilio Rigotti

Full Professor

Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE - ESCUELA DE MEDICINA - DEPTO DE GASTROENTEROLOGÍA

Santiago, Chile

1

Alejandro Godoy

Associate Professor

Centro de Biología Celular y Biomedicina

Universidad San Sebastián

Santiago, Chile

1

Marcelo Andia

Associate Professor

Radiology

Pontificia Universidad Catolica de Chile

Santiago, Chile

2

Victor Cortes

Associate professor

Nutrition, Diabetes and Metabolism

Pontificia Universidad Católica de Chile

Santiago, Chile

1

Alberto Martin

Associate professor

Centro Ciencia & Vida

Universidad San Sebastián

Santiago, Chile

7

Dolores Busso

Associate Professor

Centro de Investigación e Innovación Biomédica

Universidad de Los Andes

Santiago, Chile

2

Francisca Salas

Asistant Professor

Instituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

1

Susana Contreras

Assistant Professor

Nutrition and Dietetics

Universidad San Sebastián

Santiago, Chile

1

Guadalupe Echeverría

Manager

Center for Molecular Nutrition and Chronic Diseases

Pontificia Universidad Católica de Chile

Santiago, Chile

1

Loni Berkowitz

Investigador postdoctoral

Nutrición, diabetes y metabolismo

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

16

Nicolás Santander

Assistant Professor

Instituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

1

Aline Carvalho da Silva

Assistant Professor

Universidad de Santiago de Chile

Región metropolitana, Chile

2

Katherine Rivera

PhD (c) student in Medical Science

Pontificia Universidad Católica de Chile

Santiago, Chile

1

Leandro Murgas

Bioinformático

Meristem Spa.

Huechuraba, Chile