Man

Nicolás Guillermo Santander Grez

Investigador Postdoctoral

Universidad de O'Higgins

Rancagua, Chile

Líneas de Investigación


Metabolic regulation of brain angiogenesis

Educación

  •  Doctorado en Ciencias Médicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2018
  •  Bioquímico, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2012

Experiencia Académica

  •   Postdoctoral Scholar Full Time

    UNIVERSITY OF CALIFORNIA-SAN FRANCISCO

    San Francisco, Estados Unidos

    2019 - 2021


 

Article (12)

Bone Marrow-Derived Alk1 Mutant Endothelial Cells and Clonally Expanded Somatic Alk1 Mutant Endothelial Cells Contribute to the Development of Brain Arteriovenous Malformations in Mice
Lipoprotein receptor SR-B1 deficiency enhances adipose tissue inflammation and reduces susceptibility to hepatic steatosis during diet-induced obesity in mice
A new genetic strategy for targeting microglia in development and disease
Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier
Ovarian cholesterol efflux: ATP-binding cassette transporters and follicular fluid HDL regulate cholesterol content in mouse oocytes
Impaired alpha V beta 8 and TGF beta signaling lead to microglial dysmaturation and neuromotor dysfunction
Insulin increases cholesterol uptake, lipid droplet content, and apolipoprotein B secretion in CaCo-2 cells by upregulating SR-BI via a PI3K, AKT, and mTOR-dependent pathway
High density lipoprotein cholesterol and proteome in SR-B1 KO mice: lost in precipitation
Transcriptional profiling of embryos lacking the lipoprotein receptor SR-B1 reveals a regulatory circuit governing a neurodevelopmental or metabolic decision during neural tube closure
Deficient Vitamin E Uptake During Development Impairs Neural Tube Closure in Mice Lacking Lipoprotein Receptor SR-BI
Early Onset Intrauterine Growth Restriction in a Mouse Model of Gestational Hypercholesterolemia and Atherosclerosis
Developmental abnormalities in mouse embryos lacking the HDL receptor SR-BI

Abstract (3)

IMPAIRED NEURAL TUBE CLOSURE IN MICE LACKING HIGH DENSITY LIPOPROTEIN RECEPTOR SR-BI IS ASSOCIATED WITH DEFICIENT VITAMIN E UPTAKE AND ABERRANT GENE EXPRESSION
RNA-SEQ ANALYSIS REVEALS CANDIDATE GENES THAT MAY EXPLAIN NEURAL TUBE DEFECTS IN MOUSE EMBRYOS LACKING SR-BI
Insulin regulates SRBI and ABCG8 in a mTOR dependent pathway in CaCo-2 cells

BookWhole (1)

Nutrients and gene expression in development
16
Nicolás Santander

Investigador Postdoctoral

Instituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

6
Attilio Rigotti

Full Professor

Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE - ESCUELA DE MEDICINA - DEPTO DE GASTROENTEROLOGÍA

Santiago, Chile

6
Dolores Busso

Associate Professor

Centro de Investigación e Innovación Biomédica

Universidad de Los Andes

Santiago, Chile

2
Francisca Salas

Asistant Professor

Instituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

2
Victor Cortes

Associate professor

Nutrition, Diabetes and Metabolism

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Alejandro Godoy

Associate Professor

Centro de Biología Celular y Biomedicina

Universidad San Sebastián

Santiago, Chile

1
Alberto Martin

Assistant professor

Centro de Genómica y Bioinformática

Universidad Mayor

Santiago, Chile

1
Guadalupe Echeverría

Manager

Center for Molecular Nutrition and Chronic Diseases

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Loni Berkowitz

Profesor Asistente - Investigador postdoctoral

Nutrición, diabetes y metabolismo

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

1
Aline Carvalho da Silva

PostDoc

Universidad de O'Higgins

Región de O'Higgins, Chile