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Marcos Mauricio Fernandez Escobar

Profesor Asociado

FACULTAD DE FARMACIA, UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Controlled release drug delivery systems; Neurodegenerative diseases; Vectorization

Tecnologia Farmaceutica, Universidad Complutense de Madrid. España, 2011
Ciencias Farmacéuticas, UNIVERSIDAD DE CONCEPCION. Chile, 2006
Químico Farmacéutico, UNIVERSIDAD DE CONCEPCION. Chile, 2001

Profesor Asociado Full Time

UNIVERSIDAD DE CONCEPCION

Farmacia

Concepción, Chile

2002 - A la fecha

Docente Full Time

Universidad de Concepción

Concepcion, Chile

2002 - A la fecha
CEO y QF Encargado del Recetario Magistral Part Time

Farmacia y Recetario Magistral Innovafarma

Concepcion, Chile

2022 - A la fecha

Pregrado:
- 6 Tesis para optar al Título de Químico Farmacéutico, Universidad de Concepción, Chile

Postgrado:
- 5 Tesis, Magister en Ciencias Farmacéuticas, Universidad de Concepción, Chile.
- 1 Tesis, Doctorado en Ciencia y Tecnología Analítica, Universidad de Concepción, Chile


Impact of molecular weight and deacetylation degree of chitosan on the bioaccessibility of quercetin encapsulated in alginate/chitosan-coated zein nanoparticles Carrasco-Sandoval, Jonathan; Aranda, Mario; Henriquez-Aedo, Karem; Fernandez, Marcos; Lopez-Rubio, Amparo; Fabra, Maria Jose Article ISI INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)
Optimization of detergents in solubilization and reconstitution of Aquaporin Z: A structural approach Beratto-Ramos, Angelo; Dagnino-Leone, Jorge; Martinez-Oyanedel, Jose; Fernandez, Marcos; Aranda, Mario; Borquez, Rodrigo Article ISI BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2023)
Chemical characterization and microencapsulation of extracellular fungal pigments Contreras-Machuca, Paulina I.; Avello, Marcia; Pastene, Edgar; Machuca, Angela; Aranda, Mario; Hernandez, Vicente; Fernandez, Marcos Article ISI APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2022)
Confocal laser scanning microscopy as a novel tool of hyperspectral imaging for the localization and quantification of fluorescent active principles in pharmaceutical solid dosage forms Sanhueza, Mario, I; Castillo, Rosario del P.; Melendrez, M. F.; von Plessing, Carlos; Tereszczuk, Joanna; Osorio, German; Pena-Farfal, Carlos; Fernandez, Marcos; Neira, Jose Y. Article ISI MICROCHEMICAL JOURNAL (2021)
Dehydroascorbic acid, the oxidized form of vitamin C, improves renal histology and function in old mice Forman, Katherine; Martinez, Fernando; Cifuentes, Manuel; Fernandez, Marcos; Bertinat, Romina; Torres, Pablo; Salazar, Katterine; Godoy, Alejandro; Nualart, Francisco Article ISI JOURNAL OF CELLULAR PHYSIOLOGY (2020)
Phytochemical screening of Alstonia scholaris leaf and bark extracts and their antimicrobial activities Bagheri, Gholamreza; Ayatollahi, Seyed Abdulmajid; Ramirez-Alarcon, Karina; Fernandez, Marcos; Salehi, Bahare; Forman, Katherine; Martorell, Miquel; Moghadam, Mohammad Heydarian; Sharifi-Rad, Javad Article ISI CELLULAR AND MOLECULAR BIOLOGY (2020)
Efecto pediculicida de una formulación en base a Eucaliptus globulus L Marcia Avello; Pola Fernández; Marcos Fernández; Berta Schulz; Marta De Diego; Sigrid Mennickent; Pedro Novoa; Edgar Pastene Article ISI SCIELO SCOPUS REVISTA CHILENA DE INFECTOLOGIA (2016)
EFFECT OF GAMMA-IRRADIATION ON BIODEGRADABLE MICROSPHERES LOADED WITH RASAGILINE MESYLATE MARCOS FERNÁNDEZ; EMILIA BARCIA; SOFÍA NEGRO Article ISI SCIELO SCOPUS JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2016)
Translation and validation of a Spanish version of the xerostomia inventory. Serrano, C.; Fariña MP; Pérez C; Fernández M; Forman K.; Carrasco M. Article ISI SCOPUS GERODONTOLOGY (2016)
Desarrollo y evaluación de microesferas biodegradables para la liberación prolongada de pramipexol Fuentes, Constanza; von Plessing, Carlos; Fernández, Marcos Article Latindex Revista de Farmacología de Chile (2014)
Successful factorial design for the optimization of methylprednisolone encapsulation in biodegradable nanoparticles Gomez-Gaete, C; Bustos, GL; Godoy, RR; Saez, CK; Novoa, GP; Fernandez, EM; Tsapis, N; Fattal, E Article ISI SCOPUS Drug Development and Industrial Pharmacy (2013)
Controlled release of rasagiline mesylate promotes neuroprotection in a rotenone-induced advanced model of Parkinson's disease Fernandez, M. ; Barcia, E; Fernandez-Carballido A.; Garcia, L.; Slowing K.; Negro, S Article ISI SCOPUS International Journal of Pharmaceutics (2012)
An effective novel delivery strategy of rasagiline for Parkinson's disease Fernandez, M. ; Negro, S; Slowing K.; Fernandez-Carballido A.; Barcia, E Article ISI SCOPUS International Journal of Pharmaceutics (2011)
Development and validation of a reverse phase liquid chromatography method for the quantification of rasagiline mesylate in biodegradable PLGA microspheres Fernandez, M. ; Barcia, E; Negro, S Article ISI SCOPUS JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2009)
Validated liquid chromatographic method for quantitative determination of allicin in garlic powder and tablets De Diego M.; Avello,M.; Mennickent S.; Fernandez, M. ; Fernández P. Article ISI SCOPUS JOURNAL OF SEPARATION SCIENCE (2007)
PREPARATION AND CHARACTERIZATION OFCHITOSAN GELS Fernandez, Marcos; von Plessing, Carlos; cardenas, Galo Article SCIELO SCOPUS JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2006)
Technique validation by liquid chromatography for the determination of acyclovir in plasma Fernandez, M. ; Sepulveda, J; Aranguiz, T; Von Plessing, C Article ISI SCOPUS JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2003)
Desarrollo inicial de un fitofármaco derivado del jugo de Citrus limón (limón) para el tratamiento de crisis hipertensivas Avello L, Marcia; FernÁndez, Marcos Mauricio; Fernández R, Pola; Vallejos, Eillen Torres; Pastene, Edgar R. Article Revista chilena de cardiología


SALIVA ARTIFICIAL PARA ALIVIAR LA XEROSTOMIA, CUYA FORMULACION COMPRENDE POLIMEROS MUCOADHESIVOS, SALES MINERALES, UN AGENTE MEJORADOR DEL SABOR, UN PRESERVANTE, UN EXTRACTO DE BUDDLEJA GLOBOSA HOPE (MATICO), UN EXTRACTO DE UGNI MOLINAE TURCZ (MURTILLA) Y UN EXTRACTO DE ARISTOTELIA CHILENSIS STUNZ (MAQUI) FernÁndez, Marcos Mauricio; Forman, Katherine A.; Fariña Vélez, María Paz; MuÑoz, Cecilia M.; Serrano, Carlos; Beltran, Felipe; Avello L, Marcia Patent (2021)


Atx Plus: Validación Industrial De Un Nuevo Bioproceso De Acumulación De Astaxantina Vía Inducción No Autotrófica En Haematococcus Lacustris Para La Industria Nutracéutica Agurto, Cristian A.; FernÁndez, Marcos Mauricio Proyecto (2022)
Doble encapsulación de compuestos medicados microencapsulados a agregar en alimento de salmones INNOVA Bio Bio (14.79-IN.IEM) Proyecto 2015-2016 Coinvestigador(a)
DESIGN, DEVELOPMENT AND EVALUATION OF A CONTROLLED-RELEASE BIODEGRADABLE SYSTEM FOR PARENTAL ADMINISTRATION OF PRAMIPEXOLE. A NOVELL DELIVERY STRATEGY FOR PARKINSONS DISEASE FONDECYT (11130387) Proyecto 2013-2016 Inv. Responsable
Design, development and evaluation of controlled-release biodegradable system for parenteral administration of pramipexole. A novel delivery strategy for Parkinson's disease Fondecyt (11130387) Proyecto 2013-2016 Director(a)
Design and characterization of pharmaceutical systems for parenteral administration of capreomycin Universidad de Concepción (DIUC 212.074.048-1.0) Proyecto 2012-2014 Coinvestigador(a)
New artificial saliva formulation for the treatment of xerostomia Universidad de Concepción (212.102.014-1.0) Proyecto 2012-2014 Coinvestigador(a)
Nanocarrier of drugs across the blood-brain barrier to optimize the treatment of neurodegenerative diseases INNOVA Chile CORFO L2 (T11IDL2-10437) Proyecto 2011-2014 Coinvestigador(a)


Plant-Derived Bioactives in Oral Mucosal Lesions: A Key Emphasis to Curcumin, Lycopene, Chamomile, Aloe vera, Green Tea and Coffee Properties Salehi B.; Jornet P.L.; LÃ³pez E.P.-F.; Calina D.; Sharifi-Rad M.; RamÃrez-AlarcÃ³n K.; Forman K.; FernÃ¡ndez M.; Martorell M.; Setzer W.N.; Martins N.; Rodrigues C.F.; Sharifi-Rad J. Review ISI SCOPUS Biomolecules (2019)