Man

Patricio Cristian Smith Ferrer

Profesor Asociado

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Líneas de Investigación


Enfermedades Periodontales; Reparación de heridas, Regeneración tisular, Inflamación

Educación

  •  Biomedicina, UNIVERSIDAD DE CHILE. Chile, 2005
  •  Cirujano Dentista, UNIVERSIDAD DE CHILE. Chile, 1992
  •  Especialidad Odontológica, UNIVERSIDAD DE CHILE. Chile, 1992

Experiencia Académica

  •   Profesor Asistente Full Time

    UNIVERSIDAD DE CHILE

    Odontología

    Santiago, Chile

    1996 - 2006

  •   Profesor Asociado Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Santiago, Chile

    2007 - A la fecha


 

Article (43)

Cetylpyridinium chloride blocks herpes simplex virus replication in gingival fibroblasts
Diabetes Alters the Involvement of Myofibroblasts During Periodontal Wound Healing
Galectin-8 mediates fibrogenesis induced by cyclosporine in human gingival fibroblasts
Uncoupled inflammatory, proliferative, and cytoskeletal responses in senescent human gingival fibroblasts
Comparative effect of platelet-rich plasma, platelet-poor plasma, and fetal bovine serum on the proliferative response of periodontal ligament cell subpopulations
Chitosan-triclosan particles modulate inflammatory signaling in gingival fibroblasts
Galectin-8 induces partial epithelial-mesenchymal transition with invasive tumorigenic capabilities involving a FAK/EGFR/proteasome pathway in Madin-Darby canine kidney cells
Role of myofibroblasts in normal and pathological periodontal wound healing
Aged blood factors decrease cellular responses associated with delayed gingival wound repair
Ageing, dental caries and periodontal diseases
Glucose Promotes a Pro-Oxidant and Pro-Inflammatory Stromal Microenvironment Which Favors Motile Properties in Breast Tumor Cells
Glycated Collagen Stimulates Differentiation of Gingival Myofibroblasts
Modulation of Mammary Stromal Cell Lactate Dynamics by Ambient Glucose and Epithelial Factors
Methylglyoxal and methylglyoxal-modified collagen as inducers of cellular injury in gingival connective tissue cells.
Platelet-Poor and Platelet-Rich Plasma Stimulate Bone Lineage Differentiation in Periodontal Ligament Stem Cells
Cigarette smoke condensate inhibits collagen gel contraction and prostaglandin E-2 production in human gingival fibroblasts
Gingival wound healing: an essential response disturbed by aging?
Research on growth factors in periodontology.
The influence of platelet-derived products on angiogenesis and tissue repair: a concise update.
Defective Wound-healing in Aging Gingival Tissue.
Soluble MMP-14 produced by bone marrow-derived stromal cells sheds epithelial endoglin modulating the migratory properties of human breast cancer cells.
Synthesis of nanostructured porous silica coatings on titanium and their cell adhesive and osteogenic differentiation properties
Chitosan and platelet-derived growth factor synergistically stimulate cell proliferation in gingival fibroblasts
Effects of Chitosan Particles in Periodontal Pathogens and Gingival Fibroblasts
Tumor Necrosis Factor-alpha Inhibits Transforming Growth Factor-beta-Stimulated Myofibroblastic Differentiation and Extracellular Matrix Production in Human Gingival Fibroblasts
Effects of cigarette smoke and nicotine on cell viability, migration and myofibroblastic differentiation
Effects of platelet-rich and -poor plasma on the reparative response of gingival fibroblasts
Simvastatin alters fibroblastic cell responses involved in tissue repair.
Sonic Hedgehog Stimulates Proliferation of Human Periodontal Ligament Stem Cells
Involvement of MT1-MMP and TIMP-2 in human periodontal disease
NOX4-dependent ROS production by stromal mammary cells modulates epithelial MCF-7 cell migration.
Soluble factors derived from tumor mammary cell lines induce a stromal mammary adipose reversion in human and mice adipose cells. Possible role of TGF-beta1 and TNF-alpha.
Cigarette smoke condensate stimulates urokinase production through the generation of reactive oxygen species and activation of the mitogen activated protein kinase pathways in human gingival fibroblasts
Triclosan inhibits tumor necrosis factor-alpha-stimulated urokinase production in human gingival fibroblasts
c-jun-NH2JNK mediates invasive potential and EGFR activation by regulating the expression of HB-EGF in a urokinase-stimulated pathway
Effect of platelet-rich plasma on cell adhesion, cell migration, and myofibroblastic differentiation in human gingival fibroblasts
RAC1 activity and intracellular ROS modulate the migratory potential of MCF-7 cells through a NADPH oxidase and NFkappaB-dependent mechanism.
Differential uPA expression by TGF-beta 1 in gingival fibroblasts
Induction of the myofibroblastic phenotype in human gingival fibroblasts by transforming growth factor-beta 1: role of RhoA-ROCK and c-Jun N-terminal kinase signaling pathways
Epidermal growth factor stimulates urokinase-type plasminogen activator expression in human gingival fibroblasts. Possible modulation by genistein and curcumin
In situ detection of matrix metalloproteinase-9 (MMP-9) in gingival epithelium in human periodontal disease
Higher risk of preterm birth and low birth weight in women with periodontal disease
Periodontal therapy may reduce the risk of preterm low birth weight in women with periodontal disease=> A randomized controlled trial

BookSection (1)

Wound healing in the oral mucosa

Proyecto (9)

Gingival wound healing and aging=> Role of cellular senescence and the transcription factor FOXO1
DIABETES AS A MODULATOR OF FIBROBLASTIC CELL RESPONSES DURING PERIODONTAL WOUND HEALING
ROLE OF HPV-16 E6 AND E7 ONCOPROTEINS IN TOBACCO-SMOKE ASSOCIATED CARCINOGENESIS=> INTERACTION BETWEEN CIGARETTE SMOKE COMPONENTS (CSC) AND HPV16 E6/E7 ONCOPROTEINS IN ORAL AND BRONCHIAL EPITHELIAL CELLS AND CLINICAL SPECIMENS
EL ENVEJECIMIENTO COMO MODULADOR DE LA REGENERACION E INFLAMACION PERIODONTAL.
Desarrollo de un prototipo de producto dental para la prevención y tratamiento de la enfermedad periodontal
REPARACION TISULAR EN LOS TEJIDOS PERIODONTALES HUMANOS=> MODULACION POR TABAQUISMO Y FACTORES DE CRECIMIENTO.
MECANISMOS REGULADORES DE LA REMODELACION TISULAR EN LA ENFERMEDAD PERIODONTAL HUMANA.
ENFERMEDAD PERIODONTAL COMO POSIBLE FACTOR DE RIESGO DE PARTO PREMATURO Y DE PESO AL NACER
LESIONES BUCALES EN RELACION A LA ACCION TOPICA Y SISTEMICA DEL ALCOHOL

Review (3)

Gingival Wound Healing: An Essential Response Disturbed by Aging?
Research on growth factors in periodontology
The influence of platelet-derived products on angiogenesis and tissue repair: a concise update
21
Patricio Smith

Profesor Asociado

Odontología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

12
Patricio Smith

Associate Professor

Medicine / Dentistry

Pontificia Universidad Católica de Chile

Santiago, Chile

5
Constanza Martinez

Profesor asociado

Carrera de Odontología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE - FACULTAD DE MEDICINA CARRERA DE ODONTOLOGÍA

Santiago de Chile, Chile

5
Monica Caceres

Profesor asistente

Instituto de ciencias biomedicas

Universidad de Chile

Santiago, Chile

5
Nicolas Tobar

Assistan Professor

Cellular and molecular Biology Laboratory

INSTITUTO DE NUTRICION Y TECNOLOGIA DE LOS ALIMENTOS, INTA-UCHILE

Santiago, Chile

5
Jorge Martinez

Profesor Titular

Laboratorio de Biología Celular

INSTITUTO DE NUTRICIÓN Y TECNOLOGÍA DE ALIMENTOS (INTA), UNIVERSIDAD DE CHILE

Santiago, Chile

3
Ignacio Retamal

Docente

Universidad de Los Andes

Santiago, Chile

2
Claudia Metz

Docente Investigador

Universidad San Sebastián

Santiago, Chile

2
Omar Porras

Assistant professor

Lab. Biología Celular

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Luis González

Full Professor

School of Medicine

Universidad San Sebastián

Santiago, Chile

1
Luis Barros

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS

Valdivia, Chile

1
Francisco Melo

FULL PROFESSOR

FISICA

UNIVERSIDAD DE SANTIAGO DE CHILE

SANTIAGO, Chile

1
Leonardo Pavez

Profesor Asociado

Instituto de Ciencias Naturales

Universidad de Las Américas

Santiago, Chile

1
Christopher Holmes

Estudiante de doctorado

Ingeniería Biomédica

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Verónica Palma

Profesor Titular

Biología

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Evelyn Pardo

Investigadora Independiente

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

SANTIAGO , Chile

1
Mario Diaz

Profesor asistente

Instituto Ciencias odontológicas

UNIVERSIDAD DE CHILE FACULTAD DE ODONTOLOGIA

Santiago, Chile

1
Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

1
Fabián Jaña

Profesor Asistente

Departamento de Ciencias de la Salud

Universidad de Aysén

Coyhaique, Chile

1
Alfredo von Marttens

DIRECTOR DE ESPECIALIDAD IMPLANTOLOGÍA BUCO MAXILO FACIAL

PRÓTESIS

ESCUELA GRADUADOS, FACULTAD DE ODONTOLOGÍA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
CRISTIAN COVARRUBIAS

PROFESOR ASOCIADO

INSTITUTO DE INVESTIGACIÓN EN CIENCIAS ODONTOLÓGICAS

UNIVERSIDAD DE CHILE

SANTIAGO, Chile