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Evelyn Pardo Huguet

Investigadora Independiente

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

SANTIAGO , Chile

Líneas de Investigación


Neuroinmunología; Galectinómica; Neurociencia; Metabolismo celular; Inmunología; Autoinmunidad; Tráfico de proteínas

Educación

  •  Ciencias Biológicas m/Biología Celular y Molecular, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2013
  •  Ciencias Biológicas , PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007
  •  Bioquímico, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2009
  •  Ciencias Biológicas , PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2004

Experiencia Académica

  •   Doctorante Other

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Ciencias Biológicas

    SANTIAGO , Chile

    2008 - 2013

  •   Investigadora Other

    UNIVERSIDAD DE CHILE

    Medicina

    SANTIAGO , Chile

    2016 - 2017

  •   Post Doctorado Full Time

    Consejo Nacional de Investigación (CNR)

    Nápoles, Italia

    2014 - 2015

  •   Investigadora Independiente Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Ciencias Biológicas

    SANTIAGO, Chile

    2018 - 2018

Experiencia Profesional

  •   Profesora de Catedra y Labotatorio Part Time

    Universidad Pedro de Valdivia

    SANTIAGO , Chile

    2010 - 2012

  •   Profesora Instructor Biología Celular Part Time

    Pontificia Universidad Católica de Chile

    SANTIAGO , Chile

    2018 - 2018

Formación de Capital Humano


Tutora Tesis de pregrado Lucas Vicuña y Cristobal Curkovic.
Biol Res. 2013;46(3):275-80. doi: 10.4067/S0716-97602013000300008. Galectin-8 binds to LFA-1, blocks its interaction with ICAM-1 and is counteracted by anti-Gal-8 autoantibodies isolated from lupus patients. Vicuña L, Pardo E, Curkovic C, Döger R, Oyanadel C, Metz C, Massardo L, González A, Soza A.


Premios y Distinciones

  •   Microscopy training Fellowship

    CONSIGLIO NAZIONALE DELLE RICERCHE

    Italia, 2013

    Microscopy training Fellowship (2014-2015), Funded by Consiglio Nazionale Delle Ricerche (CNR) (Italy Government)

  •   Beca Postdoctorado

    COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

    Chile, 2012

    Postdoctoral Fellowship Program (2012-2013), Funded by Comisión Nacional de Investigación Científica y Tecnólogica (CONICYT), Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT) (Chilean Government).

  •   Beca Estudios de Doctorado

    COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

    Chile, 2006

    CONICYT Scholarship to perform graduate studies (PhD) 2006-2009. Chilean Government

  •   Beca Estudios de Doctorado. PUC

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Chile, 2009

    Scholarship for extends graduate studies (PhD) 2009-2010. Vicerrectoría Adjunta de Investigación y Doctorado (VRAID). PUC.

  •   Beca de viaje. CONICYT

    COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

    Chile, 2007

    CONICYT Travel Award. Society for Neuroscience 2007, San Diego, USA.


 

Article (17)

GALECTIN-8 Is a Neuroprotective Factor in the Brain that Can Be Neutralized by Human Autoantibodies
MTOR-independent autophagy induced by interrupted endoplasmic reticulum-mitochondrial Ca2+ communication: a dead end in cancer cells
Galectin-8 induces partial epithelial-mesenchymal transition with invasive tumorigenic capabilities involving a FAK/EGFR/proteasome pathway in Madin-Darby canine kidney cells
Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early prognostic antibodies in multiple sclerosis
Galectin-8 binds to LFA-1, blocks its interaction with ICAM-1 and is counteracted by anti-Gal-8 autoantibodies isolated from lupus patients
Galectin-8 binds to LFA-1, blocks its interaction with ICAM-1 and is counteracted by anti-Gal-8 autoantibodies isolated from lupus patients.
UTP Controls Cell Surface Distribution and Vasomotor Activity of the Human P2Y(2) Receptor through an Epidermal Growth Factor Receptor-transregulated Mechanism
UTP controls cell surface distribution and vasomotor activity of the human P2Y2 receptor through an epidermal growth factor receptor-transregulated mechanism.
Autoantibodies against galectin-8: their specificity, association with lymphopenia in systemic lupus erythematosus and detection in rheumatoid arthritis and acute inflammation
Autoantibodies against galectin-8: their specificity, association with lymphopenia in systemic lupus erythematosus and detection in rheumatoid arthritis and acute inflammation.
Galectin-8 Induces Apoptosis in Jurkat T Cells by Phosphatidic Acid-mediated ERK1/2 Activation Supported by Protein Kinase A Down-regulation
Galectin-8 induces apoptosis in Jurkat T cells by phosphatidic acid-mediated ERK1/2 activation supported by protein kinase A down-regulation.
[Antibodies against galectin-8 in patients with systemic lupus erythematosus].
Antibodies against galectin-8 in patients with systemic lupus erythematosus
Autoanticuerpos anti-galectina-8 en pacientes con lupus eritematoso sistémico
Galectin-8 binds specific beta 1 integrins and induces polarized spreading highlighted by asymmetric lamellipodia in Jurkat T cells
Galectin-8 binds specific beta1 integrins and induces polarized spreading highlighted by asymmetric lamellipodia in Jurkat T cells.

Abstract (5)

Galectin 8 autoantibodies are associated with relapsing remitting phenotype of multiple sclerosis and with higher disability scores
Galectin-8 enhances B cell antigen presentation
Galectin-8 knockout mice have sex-dependent altered homeostasis of T and B lymphocytes and autoimmune features.
Galectin-8 induces apoptotic signaling through a link between phospholipase D, PKA and ERK pathways in Jurkat cells
Autoantibodies against galectin-8 block adhesion and lamellipodia formation induced by galectin-8 in Jurkat cells

Patent (1)

Method and kit diagnose individuals with relapsing remitting Multiple Sclerosis and poor prognosis
18
Evelyn Pardo

Investigadora Independiente

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

SANTIAGO , Chile

13
Luis González

Full Professor

School of Medicine

Universidad San Sebastián

Santiago, Chile

6
Andrea Soza

Profesor Asociado

Medicina y Ciencia

Universidad San Sebastián

Santiago, Chile

4
Maria Massardo

Docente Investigador

Medicina

Universidad San Sebastián

Santiago, Chile

3
CLAUDIA CARCAMO

Profesor Asistente

neurology

PONTIFICIA UNIVERSIDADA CATÓLICA DE CHILE. DEPARTAMENTO DE NEUROLOGÍA

Santiago, Chile

3
Claudia Metz

Docente Investigador

Universidad San Sebastián

Santiago, Chile

2
Jorge Martinez

Profesor Titular

Laboratorio de Biología Celular

INSTITUTO DE NUTRICIÓN Y TECNOLOGÍA DE ALIMENTOS (INTA), UNIVERSIDAD DE CHILE

Santiago, Chile

1
Rodrigo Naves

Associate Professor

Program of Immunology

Universidad de Chile

Santiago, Chile

1
Reinaldo Uribe

Instructor Adjunto

Neurología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Alenka Lovy

Assistant Professor

Science

Universidad Mayor de Chile

Santiago, Chile

1
Fabian Montecino

Asistente de investigación

Biología Celular y Molecular

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

1
Patricio Smith

Profesor Asociado

Odontología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Christopher Holmes

Estudiante de doctorado

Ingeniería Biomédica

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Rodrigo Pacheco

Associate Investigator; Head of the Laboratory of Neuroimmunology

Fundación Ciencia para la Vida

Santiago, Chile

1
Ethel Ciampi

Instructor Adjunto

Neurología

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Cheril Tapia

Profesor Asistente

Facultad de Medicina y Ciencia

Universidad San Sebastián

Santiago, Chile

1
Eduardo Silva

Investigador Postdoctoral

Universidad Mayor

Santiago, Chile

1
Nibaldo Inestrosa

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Monica Caceres

Profesor asistente

Instituto de ciencias biomedicas

Universidad de Chile

Santiago, Chile

1
Fabián Segovia

Assistant professor

Department of Cell Biology

Universidad de Concepción

Concepción, Chile

1
María Barake

Becaria Postdoctoral

Facultad de Medicina y ciencia

Universidad San Sebastián

Santiago, Chile