Man

Gustavo Alonso Moraga Cid

Assistant Professor

UNIVERSIDAD DE CONCEPCION

Chile

Líneas de Investigación


Estructura y Funcion de Canales ionicos activados por ligando; Farmacologia de Canales Ionicos

Educación

  •  Ciencias Biologicas area Biologia Celular y Molecular, UNIVERSIDAD DE CONCEPCION. Chile, 2009
  •  Biologo Marino, UNIVERSIDAD DE CONCEPCION. Chile, 2002

Experiencia Académica

  •   Assistant Professor Full Time

    UNIVERSIDAD DE CONCEPCION

    Faculty of Biological Sciences

    Chile

    2016 - A la fecha

Experiencia Profesional

  •   Postdoctoral Fellow

    National Center of Scientific Research (CNRS)

    Francia

    2015 - A la fecha

  •   Postdoctoral Fellow

    Institut Pasteur

    Francia

    2010 - 2015

  •   Instructor

    University Andres Bello

    Chile

    2009 - 2009

  •   Instructor

    University Santo Tomas

    Chile

    2007 - 2009


 

Article (27)

Altered Glutaminase 1 Activity During Neurulation and Its Potential Implications in Neural Tube Defects
Changes in PGC-1 alpha/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model
Inhibition of the Glycine Receptor alpha 3 Function by Colchicine
Stereospecific Inhibition of Ethanol Potentiation on Glycine Receptor by M554 Stereoisomers
Data on SVCT2 transporter expression and localization in cancer cell lines and tissues
Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer.
Inhibitory actions of tropeines on the alpha3 glycine receptor function
Large Intracellular Domain-Dependent Effects of Positive Allosteric Modulators on Glycine Receptors.
Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain.
Potentiation of Gamma Aminobutyric Acid Receptors (GABAAR) by Ethanol: How Are Inhibitory Receptors Affected?
Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structure.
Intermediate closed state for glycine receptor function revealed by cysteine cross-linking.
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
A Single phenylalanine residue in the main intracellular loop of α1 γ-aminobutyric acid type A and glycine receptors influences their sensitivity to propofol.
Activated G protein α s subunits increase the ethanol sensitivity of human glycine receptors.
Allosteric modulation of retinal GABA receptors by ascorbic acid.
Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family.
Potentiation and inhibition of glycine receptors by tutin
Canonical Wnt3a modulates intracellular calcium and enhances excitatory neurotransmission in hippocampal neurons.
Molecular Requirements for Ethanol Differential Allosteric Modulation of Glycine Receptors Based on Selective G beta gamma Modulation
Blockade of Ethanol-Induced Potentiation of Glycine Receptors by a Peptide That Interferes with GB gamma Binding
A selective G betagamma-linked intracellular mechanism for modulation of a ligand-gated ion channel by ethanol.
Effects of pulp and paper mill discharges on caged rainbow trout (Oncorhynchus mykiss): Biomarker responses along a pollution gradient in the Biobio River, Chile
Molecular determinants for G protein beta gamma modulation of ionotropic glycine receptors
An RNA vaccine based on recombinant semliki forest virus particles expressing the Cu,Zn superoxide dismutase protein of Brucella abortus induces protective immunity in BALB/c mice
Reproductive, physiological, and biochemical responses in juvenile female rainbow trout (Oncorhynchus mykiss) exposed to sediment from pulp and paper mill industrial discharge areas
Intraspleen delivery of a DNA vaccine coding for superoxide dismutase (SOD) of Brucella abortus induces SOD-specific CD4(+) and CD8(+) T cells

Proyecto (7)

Targeting glycine receptors for the treatment of chronic pain, hyperekplexia and anxiety=> development of novel modulators based on recent structural and pharmacological insights
DISEÑO Y MEJORAMIENTO DE MODULADORES ALOSTÉRICOS CON ACTIVIDAD INSECTICIDA BASADO EN LA ESTRUCTURA CRISTALOGRÁFICA DEL RECEPTOR DE GABA RDL
Deciphering the functional and structural properties of the large intracellular domain of the pentameric ligand gated receptors.
Holographic Dissection of Neuronal Circuits
Molecular pharmacology of ethanol action on pentameric channel receptors based on their 3D structures=> an electrophysiological study
Structural characterization of the open and closed state of the an ionic channel from the cys loop family
“Modulation of glycine receptor by ethanol”

Review (2)

Pentameric Ligand-Gated Ion Channels as Pharmacological Targets Against Chronic Pain
Therapeutic Use of Vitamin C in Cancer: Physiological Considerations
7
Gustavo Moraga

Assistant Professor

UNIVERSIDAD DE CONCEPCION

Chile

4
Gonzalo Yévenes

Associate Professor

Universidad de Concepcion

Concepcion, Chile

4
Carola Muñoz

Profesor Asistente

Fisiología

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

3
JORGE FUENTEALBA

Dean

Physiology

UNIVERISDAD DE CONCEPCION

Concepcion, Chile

3
Gustavo Moraga

Profesor Asistente

Departamento de Fisiología

Universidad De Concepción

Concepción, Chile

2
Marcell Gatica

Profesora asistente

Bioquímica y Biología Molecular

Universidad de Concepción

Concepción, Chile

2
MAFALDA MALDONADO

PROFESOR ASOCIADO

Fisopatología

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

2
CORALIA RIVAS

Associated Professor

Pathophysiology

UNIVERSIDAD DE CONCEPCION

CONCEPCION, Chile

2
Carlos Burgos

Profesor Asistente

Fisiología

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

2
Jessica Panes

Alumna de Doctorado

Fisiología

Universidad de Concepción

Concepcion, Chile

1
Pamela Godoy

Colaboradora académica

Fisiología

Universidad de Concepción

Concepcion, Chile

1
Patricio Castro

profesor asistente

fisiologia

UNIVERSIDAD Concepcion

concepcion, Chile

1
Monica Carrasco

Profesor Asociado

Escuela de Medicina

UNIVERSIDAD DE TALCA

Talca, Chile

1
Oscar Ramírez

Estudiante de Doctorado

Fisiología

Universidad de Concepción

Concepción, Chile

1
Claudio Coddou

Profesor Asociado

Ciencias Biomédicas

Universidad Católica del Norte

Coquimbo, Chile

1
CAROLINA DELGADO

Encargado de proyectos de desarrollo de Unidad de Anatomía Patológica

CR Diagnóstico Terapéutico

Hospital Regional Concepción HGGB

Concepcion, Chile

1
mauricio gonzalez

phd

fisiopatologia

universidad de concepción

concepcion, Chile

1
Luisa Bascuñán

Profesora asistente

Botánica

Universidad de Concepción

Concepción, Chile