Man

Carola Andrea Muñoz Montesino

Profesor Asistente

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

Líneas de Investigación


Vitamin C; SVCT; mitochondrial adaptations, Oxidative stress, Cancer, Neurodegenerative diseases; Biology of Prion Diseases

Educación

  •  DOCTORADO EN CIENCIAS BIOLOGICAS AREA BIOLOGIA CELULAR Y MOLECULAR, UNIVERSIDAD DE CONCEPCION. Chile, 2009
  •  BIOLOGO, UNIVERSIDAD DE CONCEPCION. Chile, 2002

Experiencia Académica

  •   COLABORADOR DOCENTE Part Time

    UNIVERSIDAD DE CONCEPCION

    CIENCIAS BIOLOGICAS

    CONCEPCION, Chile

    2008 - 2010

Experiencia Profesional

  •   Colaborador Docente Fisiopatología

    Universidad de Concepcion

    Chile

    2008 - 2009

  •   Docente tiempo parcial Microscopía

    Universidad San Sebastian

    Chile

    2006 - 2009

  •   Docente tiempo parcial Biología Celular

    Universidad Nacional Andres Bello

    Chile

    2009 - 2009

  •   Profesor Invitado Magister Fisiología

    Universidad de Concepcion

    Chile

    2016 - 2016

  •   Investigador Postdoctoral Full Time

    Instituto Pasteur

    Paris, Francia

    2011 - 2012

  •   Investigador Postdoctoral Full Time

    Instituto Nacional de la Investigación Agronomica (INRA Jouy en Josas)

    Jouy en Josas, Francia

    2012 - 2016

  •   Director Científico Part Time

    Fundacion de Enfermedades Neurodegenerativas

    Chile

    2016 - 2020

  •   Profesor Asistente Full Time

    Universidad de Concepcion

    Concepcion, Chile

    2018 - A la fecha


 

Article (17)

A seven-residue deletion in PrP leads to generation of a spontaneous prion formed from C-terminal C1 fragment of PrP
Changes in PGC-1 alpha/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model
Inhibition of the Glycine Receptor alpha 3 Function by Colchicine
Inhibition of the glycine receptor alpha 3 function by colchicine.
Modulation of glycine receptor single-channel conductance by intracellular phosphorylation
Data on SVCT2 transporter expression and localization in cancer cell lines and tissues
Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer
Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer.
Large Intracellular Domain-Dependent Effects of Positive Allosteric Modulators on Glycine Receptors.
A stretch of residues within the protease-resistant core is not necessary for prion structure and infectivity
Sustained blockade of ascorbic acid transport associated with marked SVCT1 loss in rat hepatocytes containing increased ascorbic acid levels after partial hepatectomy
Sustained blockade of ascorbic acid transport associated with marked SVCT1 loss in rat hepatocytes containing increased ascorbic acid levels after partial hepatectomy
Generating Bona Fide Mammalian Prions with Internal Deletions
Mitochondrial ascorbic acid transport is mediated by a low-affinity form of the sodium-coupled ascorbic acid transporter-2.
Mammalian prions Tolerance to sequence changes-how far?
Vitamin C is an essential antioxidant that enhances survival of oxidatively stressed human vascular endothelial cells in the presence of a vast molar excess of glutathione
Intraspleen delivery of a DNA vaccine coding for superoxide dismutase (SOD) of Brucella abortus induces SOD-specific CD4(+) and CD8(+) T cells

Abstract (1)

Vitamin C metabolism in human cancer cells

Proyecto (4)

Abeta assemblies propagation and cell damage in Alzheimer disease
« Molecular mechanisms of structural information transfer during prion replication ».
Biología Celular y Molecular de Prion
“Protecting the food chain from prions=> shaping European priorities through basic and applied research ».

Review (1)

Therapeutic Use of Vitamin C in Cancer: Physiological Considerations
16
Carola Muñoz

Profesor Asistente

Fisiología

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

6
CORALIA RIVAS

Associated Professor

Pathophysiology

UNIVERSIDAD DE CONCEPCION

CONCEPCION, Chile

5
Gustavo Moraga

Profesor Asistente

Departamento de Fisiología

Universidad De Concepción

Concepción, Chile

4
Gustavo Moraga

Assistant Professor

UNIVERSIDAD DE CONCEPCION

Chile

4
Marcell Gatica

Profesora asistente

Bioquímica y Biología Molecular

Universidad de Concepción

Concepción, Chile

3
Jessica Panes

Alumna de Doctorado

Fisiología

Universidad de Concepción

Concepcion, Chile

3
Gonzalo Yévenes

Associate Professor

Universidad de Concepcion

Concepcion, Chile

3
mauricio gonzalez

phd

fisiopatologia

universidad de concepción

concepcion, Chile

2
Lorena Mardones

ASSOCIATED PROFESSOR

BASIC SCIENCES AND MORPHOLOGY

UNIVERSIDAD CATOLICA DE LA SANTISIMA CONCEPCION

CONCEPCION, Chile

2
Maria Escobar

Postdoctorado

Biología Molecular Vegetal

Universidad de Chile

Santiago , Chile

2
JORGE FUENTEALBA

Chairman

Physiology

UNIVERISDAD DE CONCEPCION

Concepcion, Chile

2
Carlos Burgos

Profesor Asistente

Fisiología

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

2
Patricio Castro

profesor asistente

fisiologia

UNIVERSIDAD Concepcion

concepcion, Chile

2
MAFALDA MALDONADO

PROFESOR ASOCIADO

Fisopatología

UNIVERSIDAD DE CONCEPCION

Concepción, Chile

2
Viviana Montecinos

Assistant Professor

Hematology Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

2
Hugo Folch

Professor

Immunology

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

2
PAULA GUZMÁN

Profesional Bioquímico

Laboratorio Clínico

Hospital Clínico Regional de Concepción Guillermo Grant Benavente

Concepción, Chile

1
Maria Bono

Profesor titular

Biologia

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Paula Sotomayor

Investigador

Medicina

Pontificia Universidad Católica de Chile

Santiago, Chile

1
JOSE GUZMAN

Full professor

Fisiología

Universidad de Concepción

Concepcion, Chile

1
Juan Carcamo

Profesor Titular

Instituto de Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

1
Alejandro Godoy

Associate Professor

Centro de Biología Celular y Biomedicina

Universidad San Sebastián

Santiago, Chile

1
Ana Marileo

Tesista de Doctorado

De Fisiología

Universidad de Concepción

Concepción, Chile

1
MARCELO VILLAGRAN

Profesor asociado

Departamento de Ciencias Básicas

Universidad Catolica de la Santísima Concepción

Concepcion, Chile

1
Sergio Onate

Associate Professor

Medical Specialties

UNIVERSIDAD DE CONCEPCION, DEPARTAMENTO FISIOPATOLOGIA

concepcion, Chile

1
Marcelo Bustamante

Director

Basisc Sciences

UNIVERSIDAD CATÓLICA DE LA SANTÍSIMA CONCEPCIÓN

CONCEPCIÓN, Chile

1
Juan Vera

Full professor

Pathophysiology

University of Concepcion

Concepción, Chile

1
Francisco Roa

Profesor Asistente

Fisiopatología, Facultad de Ciencias Biológicas

Universidad de Concepción

Concepción, Chile

1
Brigitte van Zundert

Full Professor

UNIVERSIDAD ANDRÉS BELLO, CENTRO DE INVESTIGACIONES BIOMÉDICAS

Santiago, Chile

1
CAROLINA DELGADO

Encargado de calidad Unidad de Anatomía Patológica

CR Diagnóstico Terapéutico

Hospital Regional Concepción HGGB

Concepcion, Chile

1
Victoria San Martín

Tesista Doctorado

Fisiologia

Universidad de Concepción

Concepción, Chile