Man

Juan Carlos Araya Oróstica

Pathologist

Hospital Dr. Hernan Henríquez Aravena

Temuco, Chile

Líneas de Investigación


gastritis, Helicobacter pylori, gastric cancer, gallbladder carcinoma, immune profile

Educación

  •  Licenciatura en Medicina, UNIVERSIDAD DE CONCEPCION. Chile, 1982
  •  Medico Cirujano, UNIVERSIDAD DE CONCEPCION. Chile, 1983
  •  Anatomia Patológica, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1987

Experiencia Académica

  •   Profesor Asociado Part Time

    UNIVERSIDAD DE LA FRONTERA

    Medicine

    Chile

    1994 - A la fecha

  •   Profesor Asistente de Anatomía Patológica Part Time

    UNIVERSIDAD DE LA FRONTERA

    Medicine

    Chile

    1991 - 1993

  •   Instructor Anatomía Patológica Part Time

    UNIVERSIDAD DE LA FRONTERA

    Medicine

    Chile

    1987 - 1990

Experiencia Profesional

  •   Jefe Centro de Responsabilidades de Laboratorios Full Time

    Hospital Dr. Hernan Henríquez Aravena

    Temuco, Chile

    2011 - 2015

  •   Jefe Unidad de Anatomía Patológica Full Time

    Hospital Dr. Hernan Henríquez Aravena

    Temuco, Chile

    2006 - 2015

  •   Attendant pathologist Part Time

    Hospital Dr. Heran Henriquez Aravena

    Temuco, Chile

    1987 - A la fecha

Formación de Capital Humano


Docencia de Pre-grado:
Curso Patología General para alumnos de 3o año de la carrera de Medicina
Curso Patología General para los alumnos de 3o año de la carrera de Odontología.
Curso de Anatomía Patológica para los alumnos de 3o an?o de la carrera de Medicina.
Curso de Anatomía Patológica para los alumnos de 3o an?o de la carrera de Odontología.

Docencia de Post-grado:
Docencia Directa en residentes de Cirugía.
Docencia Directa en residentes de Obstetricia.
Docencia Directa para Médicos Becados de la Especialidad de Anatomía Patológica.



 

Article (78)

Adenomyomas of the Gallbladder: An Analysis of Frequency, Clinicopathologic Associations, and Relationship to Carcinoma of a Malformative Lesion
Reappraisal of T1b gallbladder cancer (GBC): clinicopathologic analysis of 473 in situ and invasive GBCs and critical review of the literature highlights its rarity, and that it has a very good prognosis
Inflammatory profiles in Chilean Mapuche and non-Mapuche women with gallstones at risk of developing gallbladder cancer
Integrative molecular characterisation of gallbladder cancer reveals micro-environment-associated subtypes
T2 gallbladder cancer shows substantial survival variation between continents and this is not due to histopathologic criteria or pathologic sampling differences
The Chile Biliary Longitudinal Study: A Gallstone Cohort
Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials
Cohort Profile: The Maule Cohort (MAUCO)
Gallbladder polyps: Correlation of size and clinicopathologic characteristics based on updated definitions
Non-neoplastic Polyps of the Gallbladder: A Clinicopathologic Analysis of 447 Cases
Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer
Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group
Protocolized referral to endoscopy and Helicobacter pylori detected in stools aimed to decrease endoscopy waiting lists
Sarcomatoid carcinomas of the gallbladder: clinicopathologic characteristics
Assessment of Gastritis and Gastric Cancer Risk in the Chilean Population Using the OLGA System
Circulating Levels of Inflammatory Proteins and Survival in Patients with Gallbladder Cancer
Distribution of dysplasia and cancer in the gallbladder: an analysis from a high cancer-risk population
Poorly cohesive cell (diffuse-infiltrative/signet ring cell) carcinomas of the gallbladder=> clinicopathological analysis of 24 cases identified in 628 gallbladder carcinomas.
The ERK/MAPK pathway is overexpressed and activated in gallbladder cancer.
Association of inflammatory and other immune markers with gallbladder cancer: Results from two independent case-control studies
miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway
The Gene Expression Status of the PI3K/AKT/mTOR Pathway in Gastric Cancer Tissues and Cell Lines
[Predictive value of breast imaging report and database system (BIRADS) to detect cancer in a reference regional hospital].
Predictive value of breast imaging report and database system (BIRADS) to detect cancer in a reference regional hospital
Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice
Early gallbladder carcinoma has a favorable outcome but Rokitansky-Aschoff sinus involvement is an adverse prognostic factor
Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico.
Concordance between Gleason scores of trans rectal biopsies and the surgical piece of radical prostatectomy
Cáncer gástrico sin compromiso ganglionar linfático (pN0): características demográfico-patológicas y factores pronósticos.
Factores Asociados al pronóstico de pacientes operados por cáncer gástrico avanzado
Factores morfológicos asociados al pronóstico de pacientes operados por cáncer gástrico incipiente.
Oral and oropharingeal squamous cells carcinoma. Clinico-pathological study
Pathological factors associated with survival in advanced gastric cancer
Pathological features associated with survival in early gastric cancer
Prognostic factors for gastric cancer without lymph node involvement
Prognostic value of extracapsular lymph node involvement among patients with gastric cancer
Puntaje de Gleason en cáncer de próstata: Correlación de la biopsia por punción y prostatectomía radical
Carcinoma de células en anillo de sello gástrico: Descripción clínico-morfológica y valor pronóstico.
Changes in morphological an clinical characteristics of gastric cancer from 1986 to 2005
Descripción clínico-morfológica y factores pronósticos en carcinomas de apéndice cecal: estudio de cohorte
Hallazgos morfológicos en casos fatales de síndrome cardiopulmonar por hantavirus. Estudio de 7 autopsias.
Mesenteric cryptococcal lymphadenitis. Report of one case
Morphological findings in fatal cases of hantavirus cardiopulmonary syndrome. Report of 7 autopsies
Prognosis of signet ring cell carcinoma of the stomach
Concomitant presence of a gastric adenocarcinoma and gastrointestinal stromal tumor. Report of one case
Diagnostic value of frozen section biopsy during surgery for breast lesions or neoplasms
Promoter Methylation Profile in Preneoplastic and Neoplastic Gallbladder Lesions
Gene methylation patterns in digestive tumors
Prevalence of human papillomavirus genital infection among male university students
Prevalencia de la infección genital por virus papiloma humano en hombres universitarios voluntarios de la IX Región, Chile
Gallstones and gallbladder cancer-volume and weight of gallstones are associated with gallbladder cancer: A case-control study
Immunohistochemical expression of the E-cadherin-catenin complex in gastric cancer
Preneoplastic lesions in gallbladder cancer
Prognostic factors of phyllodes tumor of the breast
Promoter methylation profile in gallbladder cancer
Aneurysmal bone cyst of the maxilla. Report of one case
Microsatellite instability in preneoplastic and neoplastic lesions of the gallbladder
Promoter methylation profile in gastric cancer
Association between Helicobacter pylori genotype and the severity of gastritis in infected adults
Clinicopathological features of gallbladder polyps and adenomas
Detection of bone marrow micrometastases in patients with gallbladder cancer
DNA content and survival in subserous gallbladder carcinoma
Inactivation of CDKN2A gene (p16) in gallbladder carcinoma
Promoter methylation profile in breast cancer
Microsatellite instability and allelic imbalance in neoplastic and preneoplastic gastric lesions
Microsatellite instability and loss of heterozygosity in chronic gastritis
Mutations of TP53 suppressor gene in pre-neoplastic and neoplastic lesions of the stomach: cross-sectional study in a high risk region
Expression of cadherine-catenine complex in subserous gallbladder carcinoma
Is gallbladder cancer a tumor with bad prognosis?
Morphological prognostic factors in gallbladder cancer
CD44 (HCAM) expression in subserous gallbladder carcinoma
Clinical and pathological features of early gallbladder carcinoma
Pathological findings in surgical reinterventions for gallbladder cancer in patients with and without preoperative chemo and radiotherapy
Clinical features of 29 patients with hepatocellular carcinoma
Gastric cancer and tumor growth regulation. Study of cell proliferation markers and protein complex p53/p21(WAF1/CIP1)/mdm-2
Helicobacter pylori and chronic gastritis: Relationship between infection and inflammatory activity in a high risk population for gastric cancer
p53 gene mutation in colorectal carcinoma
P53 Gene mutation in gallbladder cancer

Abstract (8)

Epithelial Atypia in the Gallbladder: Diagnosis and Classification in an International Consensus Study
Marked Geographic Differences in the Pathologic Diagnosis of Non-Invasive (Tis) vs Minimally Invasive (T1) Gallbladder Cancer: Santiago Consensus Conference Highlights the Need for the Unifying Category "Early Gallbladder Cancer" (EGBC)
Not All T2 Gallbladder Carcinomas (GBC) Are Equal: Proposal for Sub- Staging of T2 GBC with Significant Prognostic Value
Not All T2 Gallbladder Carcinomas (GBC) Are Equal: Proposal for Sub-Staging of T2 GBC with Significant Prognostic Value
Prognosis of T2 Gallbladder Carcinomas: An Analysis of 326 Cases Highlights a Prognosis Better Than the Current Impression in the West, but Incomparably Worse Than What Is Reported in Asia
Biologic Behavior of Gallbladder High-Grade Dysplasia: A Long-Term Survival Analysis of 125 Cases Elucidates a Mostly Curable Disease, Which Is a Marker of Biliary Tract Cancer Risk in Some Patients
Carcinoma In-Situ of the Gallbladder: The SEER Database Perspective
Methylation profile as a prognostic factor in advanced gallbladder cancer

CaseReport (1)

Hepatocarcinoma con componente sarcomatoide: Caso clínico

EditorialMaterial (1)

Splenic sarcoidosis: a rare cause of splenectomy

Errata (2)

Author Correction: Circulating Levels of Inflammatory Proteins and Survival in Patients with Gallbladder Cancer (Scientific Reports, (2018), 8, 1, (5671), 10.1038/s41598-018-23848-8)
Early gallbladder carcinoma has a favorable outcome but Rokitansky-Aschoff sinus involvement is an adverse prognostic factor (vol 463, pg 651, 2013)

Proyecto (10)

Convenios de desempeño año 2009
Convenios de desempeño año 2008
Convenios de desempeño año 2007
Lesiones preneoplásicas de estomago en individuos con infección por helicobacter pylori=> rol protagónico de la expresión de genes ligados a la organogénesis e interacción con factores dependientes del huésped, del ambiente y de la bacteria.
Influencia del consumo exógeno de antioxidantes en el daño oxidativo de DNA en individuos con gastritis por infección por helicoacter pylori
Determinación de helicobacter pylori en la cavidad oral y lesiones gastrointestinales mediante el uso de amplificacion en nido de DNA mediado por polimerasa (PCR nested).
Patrones de respuesta inmunitaria local y general en gastritis crónica asociada a infección por helicobacter pylori.
Estudio del gen supresor de tumores p53 y su producto en lesiones precursoras y en carcinoma infiltrarte de intestino grueso importancia biológica y anatomoclinica.
Estudio de factores etiopatogenicos del carcinoma epidermoide del cuello uterino y sus lesiones precursoras, y su relación con el pronóstico.
Estudio expresión de productos de oncogenes celulares en cáncer gástrico y su relación con marcadores de proliferación y diferenciación celular.

Review (2)

Appendiceal malignant tumors. Review of 84 cases
p53 tumor supresor gene in digestive cancer
81
Juan Araya

Pathologist

Anatomía Patológica

Hospital Dr. Hernan Henríquez Aravena

Temuco, Chile

79
Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

26
Pablo Guzmán

Pathologist

Hospital Regional Dr. Hernán Henríquez Araven

Temuco, Chile

10
Carlos Manterola

Profesor Titular

Cirugía y Traumatología

Universidad de La Frontera

Temuco, Chile

7
fresia ferreccio

Full Professor, Director PhD Epidemiolgy Program

Public Health

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE FACULTAD DE MEDICINA, ESCUELA DE MEDICINA, DEPARTAMENTO DE SALUD PÚBLICA.

Santiago, Chile

6
Sergio Munoz

Profesor Titular

Salud Publica

Universidad de La Frontera

Temuco, Chile

5
Leonardo Anabalón

PROFESOR ADJUNTO

FAC RECURSOS NATURALES

UNIVERSIDAD CATOLICA DE TEMUCO

TEMUCO, Chile

4
Enrique Bellolio

Profesor asociado

Anatomía Patológica

Universidad de La F

Temuco, Chile

4
Ismael Riquelme

Académico - Investigador

Ciencias de la Salud

UNIVERSIDAD AUTÓNOMA DE CHILE

Temuco, Chile

4
Patricia García

Profesor Asistente

ANATOMIA PATOLOGICA

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

3
PAMELA LEAL

Profesor Asociado

Departamento de Ciencias Agronómicas y Recursos Naturales

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

3
Carolina Bizama

Assistant professor

Department of Pathology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

2
Johanna Acevedo

Profesor asociado investigador

Instituto de Ciencias e Innovación en Medicina (ICIM)

Universidad del Desarrollo

Santiago, Chile

2
Laura Huidobro

Encargada Investigación

Ciencias Preclínicas

Universidad Católica del Maule

Talca, Chile

2
Francisco Mucientes

Jefe de Sección

Especialidades

Universidad de Concepción

Concepción, Chile

1
Helga Weber

Investigador

Vicerrectoría de Investigación y Post Grado

Universidad de la Frontera

Temuco, Chile

1
ALEJANDRO CORVALAN

Principal Investigator

Hematology and Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Ricardo Verdugo

Asistant Professor

Facultad de Medicina

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Rocío Retamales

Consultora de análisis genómicos

Freelance

Dresden, Alemania

1
Priscilla Brebi

Profesor Asociado

Departamento de Anatomía Patológica.

Universidad de La Frontera

Temuco, Chile

1
Kurt Buchegger

Investigador Postdoctoral

Ciencias Básicas

Universidad de La Frontera

Temuco, Chile

1
Claudia Foerster

Associate Professor

Institute of Agri-food, Animal and Environmental Sciences

Universidad de O'Higgins

San Fernando, Chile

1
Vanessa Van De Wyngard

Investigadora

Escuela de Medicina

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Juan Orellana

Asistente A

Salud Pública

Universidad de La Frontera

Temuco, Chile

1
Arnoldo Riquelme

Profesor titular

Gastroenterología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE GASTROENTEROLOGÍA

Santiago, Chile

1
Cristian Yáñez

Ingeniero Bioinformático y desarrollados de software

Meristem SpA

Santiago, Chile

1
Bruno Nervi

Associated Professor

Hematology - Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
CLAUDIA BAMBS

PROFESORA ASOCIADA

SALUD PÚBLICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Hugo Verdejo

Profesor Asociado

División de Enferemedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Pablo Castro

JEFE DIVISION

DIVISION ENFERMEDADES CARDIOVASCULARES

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

1
Antonio Sanhueza

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

1
Gonzalo De Toro

MEDICO ANATOMOPATOLOGO

HOSPITAL DE PUERTO MONTT - LABORATORIO DE ANATOMIA PATOLOGICA Y BIOLOGIA MOLECULAR

PUERTO MONTT, Chile

1
Carmen Ili

Academico Asociado

Scientific and technological Bioresource Nucleus (BIOREN)

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

1
Erik Morales

Profesor Auxiliar

Ciencias Preclínicas

UNIVERSIDAD CATÓLICA DEL MAULE

Talca, Chile

1
Pablo Letelier

Docente Planta Permanente (Instructor)

UNIVERSIDAD CATOLICA DE TEMUCO

temuco, Chile