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Ramiro Araya Maturana

Profesor Titular

Universidad de Talca

SantiaTalcago, Chile

Estrategias Quimioterapeuticas para el tratamiento de la Enfermedad de Chagas; FunciÃ³n endotelial en cardiopatÃa crÃ³nica de origen infeccioso; Biochemistry - Bioenergetic; Oxidative Phosphorylation System of Cancer Cells; Multiresistance Mechanisms to Chemotherapeutic Agents; SÃntesis OrgÃ¡nica; Productos Naturales; QuÃmica Medica; QuÃmica OrgÃ¡nica; QuÃmica Medicinal; Espectrocopia

Síntesis Orgánica, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1990
Química Orgánica, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1990

Professor Full Time

Universidad de Chile

Santiago, Chile

2008 - 2015


Linking triphenylphosphonium cation to a bicyclic hydroquinone improves their antiplatelet effect via the regulation of mitochondrial function Article WOS REDOX BIOLOGY (2024)
A New Quinone-Based Inhibitor of Mitochondrial Complex I in D-Conformation, Producing Invasion Reduction and Sensitization to Venetoclax in Breast Cancer Cells Andrades, Victor; Almarza, Cristopher; Martinez, Jorge Article ISI ANTIOXIDANTS (2023)
Assessing mitochondria-targeted acyl hydroquinones on the mitochondrial platelet function and cytotoxic activity: Role of the linker length Alfaro, Sergio; Caballero, Julio; Fuentes, Eduardo Article ISI FREE RADICAL BIOLOGY AND MEDICINE (2023)
Assessment of the Long-Range NMR C,H Coupling of a Series of Carbazolequinone Derivatives Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
Pictolysin-III, a Hemorrhagic Type-III Metalloproteinase Isolated from <i>Bothrops pictus</i> (Serpentes: Viperidae) Venom, Reduces Mitochondrial Respiration and Induces Cytokine Secretion in Epithelial and Stromal Cell Lines Rosas, Paola; Tenorio-Ricca, Ana Belen; Guajardo, Francisco; Oropesa, Daniel; Toledo, Jorge; Martinez, Jorge; Hermoso, Marcela A. A.; Oliveira, Luciana Souza Article ISI PHARMACEUTICS (2023)
The Use of Triphenyl Phosphonium Cation Enhances the Mitochondrial Antiplatelet Effect of the Compound Magnolol Mansilla, Santiago Article ISI PHARMACEUTICALS (2023)
An In Vitro and In Silico Study of Antioxidant Properties of Curcuminoid N-alkylpyridinium Salts: Initial Assessment of Their Antitumoral Properties Article ISI ANTIOXIDANTS (2022)
In Vitro Effect of Mitochondria-Targeted Triphenylphosphonium-Based Compounds (Honokiol, Lonidamine, and Atovaquone) on the Platelet Function and Cytotoxic Activity Fuentes, Eduardo Article ISI FRONTIERS IN PHARMACOLOGY (2022)
Novel N-benzoylimidazolium ionic liquids derived from benzoic and hydroxybenzoic acids as therapeutic alternative against Biofilm-forming bacteria in skin and soft-tissue infections Espinoza, Carolina; Leiva, Angel Article ISI BIOORGANIC CHEMISTRY (2022)
Study of the Electrochemical Behavior of N-Substituted-4-Piperidones Curcumin Analogs: A Combined Experimental and Theoretical Approach Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Characterization of an anionic membrane mimetic with natural phospholipid content and magnetic orienting capabilities Article ISI JOURNAL OF MOLECULAR LIQUIDS (2021)
Synthesis and pharmacological evaluation of acylhydroquinone derivatives as potent antiplatelet agents Article ISI BIOCHEMICAL PHARMACOLOGY (2021)
An acylhydroquinone derivative produces OXPHOS uncoupling and sensitization to BH3 mimetic ABT-199 (Venetoclax) in human promyelocytic leukemia cells Pablo Millas-Vargas, Juan; Correa, Pablo; Miranda, Dante; Pulgar, Rodrigo Article ISI BIOORGANIC CHEMISTRY (2020)
Mitoquinone (MitoQ) Inhibits Platelet Activation Steps by Reducing ROS Levels Fuentes, Francisco; Zorzano, Antonio; Fuentes, Eduardo Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Nitrofuran drugs beyond redox cycling: Evidence of Nitroreduction-independent cytotoxicity mechanism Article ISI TOXICOLOGY AND APPLIED PHARMACOLOGY (2020)
Synthesis and Biological Evaluation of Thio-Derivatives of 2-Hydroxy-1,4-Naphthoquinone (Lawsone) as Novel Antiplatelet Agents Article ISI FRONTIERS IN CHEMISTRY (2020)
Synthesis of antiplatelet ortho-carbonyl hydroquinones with differential action on platelet aggregation stimulated by collagen or TRAP-6 Mendez, Diego; Rodríguez-Lavado, Julio; Fuentes, Eduardo Article ISI SCOPUS (2020)
Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed Ligands Quiroz, Gabriel; Cabezas, David Article ISI MOLECULES (2020)
Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease Osorio, Rodrigo; Jaque, Pablo Article ISI EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Assessing Parameter Suitability for the Strength Evaluation of Intramolecular Resonance Assisted Hydrogen Bonding in o-Carbonyl Hydroquinones Martinez-Cifuentes, M; Monroy-Cardenas, M; Millas-Vargas, JP; Weiss-Lopez, BE; Araya-Maturana, R. Article MOLECULES (2019)
Characterisation of a new nematic lyotropic liquid crystal with natural lipids from soybean Ruiz-Fernandez, AR; Tejos, R; Ahumada-Gutierrez, H; Munoz-Gacitua, D; Martinez-Cifuentes, M; Araya-Maturana, R; Weiss-Lopez, BE. Article MOLECULAR PHYSICS (2019)
Detoxification Mechanism of 8,8-Dimethyl-3-[(R-phenyl)amino]-1,4,5(8H)-naphthalentrione Derivatives by Botrytis cinerea Mendoza, L; Vivanco, M; Melo, R; Castro, P; Araya-Maturana, R; Cotoras, M. Article MOLECULES (2019)
Regulation of mitochondrial function as a promising target in platelet activation-related diseases Fuentes, E; Araya-Maturana, R; Urra, FA. Article FREE RADICAL BIOLOGY AND MEDICINE (2019)
FR58P1a; a new uncoupler of OXPHOS that inhibits migration in triple-negative breast cancer cells via Sirt1/AMPK/beta 1-integrin pathway Urra, FA; Munoz, F; Cordova-Delgado, M; Ramirez, MP; Pena-Ahumada, B; Rios, M; Cruz, P; Ahumada-Castro, U; Bustos, G; Silva-Pavez, E; Pulgar, R; Morales, D; Varela, D; Millas-Vargas, JP; Retamal, E; Ramirez-Rodriguez, O; Pessoa-Mahana, H; Pavani, M; Ferreira, J; Cardenas, C; Araya-Maturana, R. Article SCIENTIFIC REPORTS (2018)
Molecular dynamics characterization of silver colloidal interfaces for SERS applications. Gallic acid test Munoz-Gacitua, D; Garrido, C; Ruiz-Fernandez, A; Ahumada, Campos-Vallette; Araya-Maturana, R ; Weiss-Lopez, BE Article JOURNAL OF RAMAN SPECTROSCOPY (2018)
Platelet mitochondrial dysfunction and mitochondria-targeted quinone-and hydroquinone-derivatives=> Review on new strategy of antiplatelet activity Fuentes, M; Araya-Maturana, R; Palomo, I; Fuentes, E. Article BIOCHEMICAL PHARMACOLOGY (2018)
Synthesis and biological evaluation of potential acetylcholinesterase inhibitors based on a benzoxazine core Mendez-Rojas, C; Quiroz, G; Faundez, M; Gallardo-Garrido, C; Pessoa-Mahana, CD; Chung, H; Gallardo-Toledo, E; Saitz-Barria, C; Araya-Maturana, R; Kogan, MJ; Zuniga-Lopez, MC; Iturriaga-Vasquez, P; Valenzuela-Gutierrez, C; Pessoa-Mahana, H Article ARCHIV DER PHARMAZIE (2018)
A Study about Regioisomeric Hydroquinones with Multiple Intramolecular Hydrogen Bonding Martínez-Cifuentes Maximiliano, Cardona Wilson; Saitz Claudio, Weiss-López Boris Article MOLECULES (2017)
Ethyl (1R,10S,12R,15S)-4-Hydroxy-2-oxo-15- (2-oxo-1-pyrrolidinyl)-9-oxatetracyclo[10.2.2.01,10.03,8]hexadeca-3,5,7,13-tetraene-13-carboxylate Heredia-Moya Jorge, Araya-Maturana Ramiro Article MolBank (2017)
Experimental and Theoretical Reduction Potentials of Some Biologically Active ortho-Carbonyl para-Quinones Martínez-Cifuentes Maximiliano, Salazar Ricardo; Ramírez-Rodríguez Oney, Weiss-López Boris Article MOLECULES (2017)
Synthesis and docking of novel 3-indolpropyl derivatives as new polypharmacological agents displaying affinity for 5-HT1AR/SERT Pessoa-Mahana Hernán, Silva-Matus Paul; Pessoa-Mahana Carlos D, Chung Hery; Iturriaga-Vasquez Patricio, Quiroz Gabriel; Moller-Acuña Patricia, Zapata-Torres Gerald; Saitz-Barria Claudio, Araya-maturana Ramiro Article ARCHIV DER PHARMAZIE (2017)
Theoretical study about the effect of halogen substitution on the reactivity of antitumor 3-formylchromones and their free radicals Martínez-Cifuentes Maximiliano, Weiss-López Boris Article Journal of Chemistry (2017)
A computational study of structure and reactivity of N-substituted-4-piperidones curcumin analogues and their radical anions Martínez-Cifuentes Maximiliano, Weiss-López Boris Article MOLECULES (2016)
Effect of shape and bending modulus on the properties of nematic lyotropic liquid crystals Ruiz-Fernandez, AR; Lopez-Cascales, JJ; Giner-Casares, JJ; Araya-Maturana, R; Diaz-Banos, FG; Munoz-Gacitua, D; Weiss-Lopez, BE Article ISI SCOPUS RSC ADVANCES (2016)
Protonation sites, Tandem mass spectrometry and computational calculations of o-carbonyl carbazolequinones derivatives Martínez-Cifuentes Maximiliano, Clavijo-Allancan Graciela; Zuñiga-Hormazabal Pamela, Aranda Braulio; Barriga Andrés, Weiss-López Boris Article INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Small structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of tumoral oxidative phosphorylation Urra, Félix A; Cordova-Delgado, Miguel; Lapier, Michel; Orellana-Manzano, Andrea; Acevedo-Arevalo, Luis; Pessoa-Mahana, Hernan; Gonzalez-Vivanco, Jaime M; Martinez-Cifuentes, Maximiliano; Ramirez-Rodriguez, Oney; Millas-Vargas, Juan P; Weiss-Lopez, Boris; Pavani, Mario; Ferreira, Jorge; Araya-Maturana, Ramiro Article TOXICOLOGY AND APPLIED PHARMACOLOGY (2016)
Action mechanism for 3 beta-hydroxykaurenoic acid and 4,4-dimethylanthracene-1,9,10(4H)-trione on Botrytis cinerea Mendoza, L; Ribera, A; Saavedra, A; Silva, E.; Araya-Maturana, R; Cotoras, M. Article ISI SCOPUS Mycologia (2015)
Correlating experimental electrochemistry and theoretical calculations in 2 '-hydroxy chalcones: the role of the intramolecular hydrogen bond Martinez-Cifuentes, M; Salazar, R.; Weiss-Lopez, BE; Santos, LS; Araya-Maturana, R Article ISI SCOPUS RSC Advances (2015)
Electrochemical characterization of hydroquinone derivatives with different substituents in acetonitrile Salazar, R.; Vidal, J; Martinez-Cifuentes, M; Araya-Maturana, R; Ramirez-Rodriguez O. Article ISI SCOPUS NEW JOURNAL OF CHEMISTRY (2015)
Heterocyclic Curcumin Derivatives of Pharmacological Interest: Recent Progress Martinez-Cifuentes, Maximiliano ; Weiss-Lopez, Boris; Santos, Leonardo S.; Araya-Maturana, Ramiro Article CURRENT TOPICS IN MEDICINAL CHEMISTRY (2015)
Factors affecting the competitive reduction of 8,8-dimethylnaphthalene-1,4,5(8H)-trione in a Diels-Alder cycloaddition with hydroxysulfinyldienes Almodovar, I; Cardona W.; Delgado-Castro, T; Zapata-Torres, G; Araya-Maturana, R Article ISI SCOPUS JOURNAL OF THE IRANIAN CHEMICAL SOCIETY (2014)
Intramolecular Hydrogen Bond in Biologically Active o-Carbonyl Hydroquinones Martinez-Cifuentes, M; Weiss-Lopez, BE; Santos, LS; Araya-Maturana, R Article SCOPUS MOLECULES (2014)
On-Water Reactivity and Regioselectivity of Quinones in C-N Coupling with Amines: Experimental and Theoretical Study Martinez-Cifuentes, M; Clavijo-Allancan, G; Di Vaggio-Conejeros, C; Weiss-Lopez, B; Araya-Maturana, R Article ISI SCOPUS AUSTRALIAN JOURNAL OF CHEMISTRY (2014)
Thermodynamics and (HNMR)-H-2 Study on the Insertion of Small Quinones into a Discotic Nematic Lyotropic Liquid Crystal Bahamonde-Padilla, VE; Lopez-Cascales, JJ; Araya-Maturana, R; Martinez-Cifuentes, M; Lopez, BEW Article ISI SCOPUS CHEMPHYSCHEM (2014)
An ortho-carbonyl substituted hydroquinone derivative is an anticancer agent that acts by inhibiting mitochondrial bioenergetics and by inducing G(2)/M-phase arrest in mammary adenocarcinoma TA3 Urra, FA; Martinez-Cifuentes, M; Pavani, M.; Lapier, M.; Jana-Prado, F; Parra, E; Pessoa-Mahana H.; Ferreira J.; Araya-Maturana, R Article ISI SCOPUS TOXICOLOGY AND APPLIED PHARMACOLOGY (2013)
Aspergillus niger catalyzes the synthesis of flavonoids from chalcones Alarcón, J; Alderete J.; Escobar, C; Araya, R Article ISI SCOPUS Biocatalysis and Biotransformation (2013)
Effect of lithium on the properties of a liquid crystal formed by sodium dodecylsulphate and decanol in aqueous solution Bahamonde-Padilla, VE; Espinoza, J; Weiss-Lopez, BE; Cascales, JJL; Montecinos R.; Araya-Maturana, R Article ISI SCOPUS Journal of Chemical Physics (2013)
Mitochondria: A Promising Target for Anticancer Alkaloids (Urra, Felix A. ; Cordova-Delgado, Miguel ; Pessoa-Mahana, Pessoa-Mahana, Hernan; Ramirez-Rodriguez, Oney; Weiss-Lopez, Boris; Ferreira, Jorge; Araya-Maturana, Ramiro Article CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)
On the mechanism of biological activity of hydroquinone derivatives that inhibit tumor cell respiration. A theoretical study Soto-Delgado, J; Bahamonde-Padilla, V; Araya-Maturana, R; Weiss-Lopez, BE Article ISI SCOPUS Computational and Theoretical Chemistry (2013)
Remote regio- and stereocontrol by the sulfinyl group: Diels-Alder reaction of sulfinyl dienols and 8,8-dimethylnaphthalene-1,4,5(8H)-trione Almodovar, I; Cardona W.; Delgado-Castro, T; Zapata-Torres, G; Araya-Maturana, R; Maestro, MC; Ruano, JLG Article ISI SCOPUS Tetrahedron Asymmetry (2013)
Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole derivatives at SERT and 5-HT1A receptor Pessoa-Mahana H.; Gonzalez-Lira, C; Fierro, A; Zapata-Torres, G; Pessoa-Mahana, CD; Ortiz-Severin, J; Iturriaga-Vásquez, P; Reyes-Parada, M; Silva-Matus, P; Saitz-Barria, C; et al. Article ISI SCOPUS Bioorganic and Medicinal Chemistry (2013)
Location, orientation and dynamics of two molecules with mitochondrial activity dissolved in anionic lyomesophase. A 2H-NMR and MD study Martinez-Cifuentes, M; Munoz-Masson, D; Ruiz, A; Ahumada, H; Araya-Maturana, R; Soto-Delgado, J Article SCOPUS JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2012)
LOCATION, ORIENTATION AND DYNAMICS OF TWO MOLECULES WITH MITOCHONDRIAL ACTIVITY DISSOLVED IN ANIONIC LYOMESOPHASE. A H-2-NMR AND MD STUDY Bahamonde-Padilla, VE; Martinez-Cifuentes, M; Munoz-Masson, D; Ruiz, A; Ahumada, H; Araya-Maturana, R; Soto-Delgado, J; Weiss-Lopez, BE Article ISI JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2012)
Remote stereocontrol by the sulfinyl group. Diels-Alder reaction of cyclopentadiene with substituted (S)-[2-(p-tolylsulfinyl)styrenes and (S)2-(p-tolylsulfinyl)phenyl] vinyl ketones Garcia Ruano J.L.; Araya-Maturana, R Article ISI SCOPUS Tetrahedron (2012)
SYNTHESIS OF 1-BENZYL-3-[4-(ARYL-1-PIPERAZINYL) CARBONYL]-1H-INDOLES. NOVEL LIGANDS WITH POTENTIAL D4 DOPAMINERGIC ACTIVITY (vol 56, pg 866, 2011) Pessoa-Mahana H.; Cuevas, MI; Pessoa-Mahana, CD; Araya-Maturana, R; Fajardo, IA; Barria, CS Article JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2012)
Synthesis, 5-Hydroxytryptamine(1A) Receptor Affinity and Docking Studies of 3-[3-(4-Aryl-1-piperazinyl)-propyl]-1H-Indole Derivatives Pessoa-Mahana H.; Nunez, CU; Araya-Maturana, R; Barria, CS; Zapata-Torres, G; Pessoa-Mahana, CD; Iturriaga-Vásquez, P; Mella-Raipan J.; Reyes-Parada, M; Celis-Barros, C Article ISI CHEMICAL PHARMACEUTICAL BULLETIN (2012)
Synthesis, Docking Studies and Biological Evaluation of Benzo[b]thiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1-one Derivatives on 5-HT1A Serotonin Receptors Pessoa-Mahana H.; Recabarren-Gajardo G.; Zapata-Torres, G; Araya-Maturana, R Article ISI SCOPUS MOLECULES (2012)
Electrospray ionization mass spectrometric fragmentation of hydroquinone derivatives Almodovar, I; Rezende M.C.; Ramirez-Rodriguez O.; Araya-Maturana, R; Barriga, A. Article ISI SCOPUS Rapid Communications in Mass Spectrometry (2011)
NMR assignment in regioisomeric hydroquinones Dobado, JA; Gomez-Tamayo, JC; Calvo-Flores, FG; Martinez-Garcia H.; Cardona W.; Weiss-Lopez, B; Ramirez-Rodriguez O.; Pessoa-Mahana H.; Araya-Maturana, R Article ISI SCOPUS Magnetic Resonance in Chemistry (2011)
SYNTHESIS OF 1-BENZYL-3-[4-(ARYL-1-PIPERAZINYL) CARBONYL]-1H-INDOLES. NOVEL LIGANDS WITH POTENTIAL D4 DOPAMINERGIC ACTIVITY Pessoa-Mahana H.; Cuevas, MI; Pessoa-Mahana, D.; Araya-Maturana, R; Fajardo, IA; Barria, CS Article ISI SCIELO SCOPUS Journal of the Chilean Chemical Society (2011)
Counterion Effects and Dynamics of Parathion in Anionic Lyomesophases Bahamonde, V; Ahumada, H; Araya-Maturana, R; Weiss-Lopez, BE Article ISI SCOPUS Australian Journal of Chemistry (2010)
8,8-Diethyl-1,4,5,8-tetrahydronaphthalene-1,4,5-trione Vega, A; Ramirez-Rodriguez O.; Martinez-Cifuentes, M; Ibañez, A; Araya-Maturana, R Article ISI SCOPUS ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE (2009)
Chemosensitizing Effect of Nordihydroguaiaretic Acid and its Tetra-acetylated Derivative on Parental and Multiresistant TA3 Mouse Mammary Adenocarcinoma Cells Plaza C.; Pavani, M.; Araya-Maturana, R; Pezoa, J.; Morello A.; De Ioannes, A.; Ferreira J. Article ISI SCOPUS IN VIVO (2009)
Solvent-free microwave-promoted Michael addition of aza-nucleophiles to benzo[b] thiophen-2-yl-2-propenone Pessoa-Mahana H.; Gonzalez, M.; Gonazlez, M; Pessoa-Mahana, D.; Araya-Maturana, R; Ron, N; Saitz C. Article ISI ARKIVOC (2009)
Solvent-free microwave-promoted Michael addition of azanucleophiles to benzo[b]thiophen-2-yl-2-propenone Pessoa-Mahana H.; Gonzalez, M.; Araya-Maturana, R; Ron, N; Saitz C.; Pessoa-Mahana, D. Article SCOPUS ARKIVOC (2009)
Synthesis of 1,5-Benzodiazepines with Unusual Substitution Pattern from Chalcones Under Solvent-Free Microwave Irradiation Conditions Donoso-Tauda, O; Araya-Maturana, R; Sicker, D Article ISI SCOPUS SYNTHETIC COMMUNICATIONS (2009)
SYNTHESIS OF CONFORMATIONALLY RESTRICTED N-{4-[4-(4,7-DIMETHOXY-BENZO[b]THIOPHENE-2-CARBONYL)-1-PIPERAZINYL]-PHENYL}-ARYLCARBOXAMIDES POTENTIAL LIGANDS WITH 5-HT1A BINDING AFFINITY Pessoa-Mahana H.; González, C; Araya-Maturana, R; Saitz C.; Pessoa-Mahana, CD Article ISI SCIELO SCOPUS JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2009)
Understanding the stereo- and regioselectivities of the polar Diels-Alder reactions between 2-acetyl-1,4-benzoquinone and methyl substituted 1,3-butadienes: a DFT study Soto-Delgado, J; Domingo, LR; Araya-Maturana, R; Contreras, R Article ISI SCOPUS JOURNAL OF PHYSICAL ORGANIC CHEMISTRY (2009)
4-Acetyl-3,3-diethyl-5-hydroxy-2-morpholino-2,3-dihydro-1-benzofuran Vega, A; Ramirez-Rodriguez O.; Martinez-Cifuentes, M; Ibañez, A; Araya-Maturana, R Article ISI SCOPUS ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE (2008)
9,10-dihydroxy-4,4-dimethyl-5,8-dihydroanthracen-1(4H)-one Ramirez-Rodriguez O.; Martinez-Cifuentes, M; Ibañez, A; Vega, A; Araya-Maturana, R Article ISI SCOPUS ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE (2008)
Dynamics and Orientation of Parathion Dissolved in a Discotic Nematic Lyomesophase Vera, A; Ahumada, H; Bahamonde, V; Montecinos R.; Araya-Maturana, R; Munoz, D; Weiss-Lopez, BE Article ISI SCOPUS AUSTRALIAN JOURNAL OF CHEMISTRY (2008)
Effects of simple and angular chromones on tumor cell respiration Araya-Maturana, R; Heredia-Moya, J; Donoso-Tauda, O; Vera, M; Hernandez, JT; Pavani, M.; Pessoa-Mahana H.; Weiss-Lopez, B; Ferreira J. Article ISI SCOPUS NATURAL PRODUCT COMMUNICATIONS (2008)
Solvent-free microwave synthesis of 3-(4-benzo[b]-thiophene-2-carbonyl)-1-piperazinyl-1-benzo[b]thiophen-2-YL-1-propanones. New hetero bis-ligands with potential 5-HT1A serotonergic activity Pessoa-Mahana H.; Kosche C. J.; Ron H. N.; Recabarren-Gajardo G.; Saitz B. C.; Araya-Maturana, R Article SCOPUS HETEROCYCLES (2008)
Very long-range correlations ( nJ C,H n > 3) in HMBC spectra Araya-Maturana, R; Pessoa-Mahana H.; Weiss-Lopez, B Article NATURAL PRODUCT COMMUNICATIONS (2008)
4-(2-Hydroxyphenyl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine and the 2-(2,3-dimethoxyphenyl)-, 2-(3,4-dimethoxyphenyl)- and 2-(2,5-dimethoxyphenyl)-substituted derivatives Donoso-Tauda, O; Araya-Maturana, R; Vega, A Article ISI SCOPUS ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS (2007)
Antioxidant properties and free radical-scavenging reactivity of a family of hydroxynaphthalenones and dihydroxyanthracenones Rodríguez, J; Olea Azar C.; Cavieres, C; Norambuena E.; Delgado-Castro, T; Soto-Delgado, J; Araya-Maturana, R Article ISI SCOPUS BIOORGANIC & MEDICINAL CHEMISTRY (2007)
Domino inverse electron demand Diels-Alder reactions of chromones with ethyl vinyl ether Heredia-Moya, J; Krohn, K; Florke, U; Pessoa-Mahana H.; Weiss-Lopez, B; Estevez-Braun, A; Araya-Maturana, R Article ISI HETEROCYCLES (2007)
Synthesis of 2-benzothienyl carbonyl 4-arylpiperazines as novel delavirdine analogs Pessoa-Mahana H.; Acevedo, RR; Saitz, BC; Araya-Maturana, R; Pessoa-Mahana, CD Article ISI SCOPUS SYNTHETIC COMMUNICATIONS (2007)
Synthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: Potential Ligands with 5-HT1A binding affinity Pessoa-Mahana H.; Acevedo, R; Araya-Maturana, R; Saitz C.; Pessoa-Mahana, CD Article ISI SCOPUS SYNTHETIC COMMUNICATIONS (2007)
(1 alpha, 12 alpha)-Ethyl 15-ethoxy-4-hydroxy-2-oxo-9-oxatetracyclo[10.2.2.0(1,10).0(3,8)]hexadeca-4,6,8,13-tetraene-13-carboxylate Heredia-Moya, J; Krohn, K; Florke, U; Araya-Maturana, R Article ISI SCOPUS ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE (2006)
(2S,R-S)-6-Phenyl-1-(p-tolylsulfinyl)-hexa-3(E),5(E)-dien-2-ol Donoso-Tauda, O; Araya-Maturana, R; Vega, A Article ISI SCOPUS ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS (2006)
Effects of 9,10-dihydroxy-4,4-dimethyl-5,8-dihydro-1(4H)-anthracenone derivatives on tumor cell respiration Araya-Maturana, R; Cardona W.; Delgado-Castro, T; Ferreira J.; Miranda, D; Pavani, M.; Pessoa-Mahana H.; Soto-Delgado, J; Weiss-Lopez, B Article ISI SCOPUS BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Electrochemical approach to the radical anion formation from 2 '-hydroxy chalcone derivatives Quintana-Espinoza, P; Yáñez, C; Sicker, D; Araya-Maturana, R; Squella, JA Article ISI SCOPUS ELECTROANALYSIS (2006)
(2Z)-3-(5-hydroxy-4-oxo-4H-chromen-3-yl)acrylonitrile Araya-Maturana, R; Heredia-Moya, J; Pessoa-Mahana H.; Weiss-Lopez, B; Muñoz, JC Article ISI SCOPUS ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS (2005)
A facile approach for new dibenzo [b,f][1,5] diazocinones Pessoa-Mahana H.; Aranguiz, KGM; Araya-Maturana, R; Pessoa-Mahana, CD Article ISI SCOPUS SYNTHETIC COMMUNICATIONS (2005)
Chiral discrimination of L- and D-N-acyl-1-phenyl-D-5-2-aminopropanes in a cesium N-dodecanoyl-L-threoninate cholesteric nematic lyomesophase Ahumada, H; Montecinos R.; Alegria, S; Araya-Maturana, R; Weiss-Lopez, BE Article ISI JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2005)
In vitro sensitivity of Botrytis cinerea to anthraquinone and anthrahydroquinone derivatives Mendoza, L; Araya-Maturana, R; Cardona W.; Delgado-Castro, T; García, C; Lagos, C; Cotoras, M. Article ISI SCOPUS JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2005)
Long-range correlations ((n)j (C,H) n > 3) in the HMBC spectra of 3-(4-oxo-4H-chromen-3-YL)-acrylic acid ethyl esters Araya-Maturana, R; Gavin-Sazatornil, JA; Heredia-Moya, J; Pessoa-Mahana H.; Weiss-Lopez, B Article ISI JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY (2005)
About the difference in the quadrupole splitting of water between cationic and anionic nematic lyotropic liquid crystals. H-2-NMR and molecular dynamics study Ahumada, H; Montecinos R.; Martínez, R; Araya-Maturana, R; Weiss-Lopez, B Article ISI JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2004)
ABOUT THE DIFFERENCE IN THE QUADRUPOLE SPLITTING OF WATER BETWEEN CATIONIC AND ANIONIC NEMATIC LYOTROPIC LIQUID CRYSTALS: 2H-NMR AND MOLECULAR DYNAMICS STUDY Ahumada, H; Montecinos R.; Martínez, R; Araya-Maturana, R; Weiss-Lopez, B Article SCIELO SCOPUS JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2004)
On the reduction of 4-oxo-4H-benzopyran-3-carbaldehydes: Global and local electrophilicity patterns Araya-Maturana, R; Heredia-Moya, J; Escobar C.A.; Pérez, P Article SCOPUS JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2004)
On the reduction of 4-oxo-4H-benzopyran-3-carbaldehydes: Global and local electrophilicity patternse Araya-Maturana, R; Heredia-Moya, J; Pérez, P Article ISI JOURNAL OF THE CHILEAN CHEMICAL SOCIETY (2004)
Solvent-free synthesis of 6-arylbenzimidazo[1,2-c]quinazolines under microwave irradiation Pessoa-Mahana H.; Pessoa-Mahana, CD; Salazar, R.; Sáez, E.; Araya-Maturana, R Article ISI SCOPUS SYNTHESIS-STUTTGART (2004)
Structure and aggregation number of a lyotropic liquid crystal: A fluorescence quenching and molecular dynamics study Montecinos R.; Ahumada, H; Martínez, R; Olea, FA; Araya-Maturana, R; Aliste, MP; Tieleman, DP; Weiss-Lopez, BE Article ISI SCOPUS LANGMUIR (2004)
Synthesis of 4-arylpiperazine derivatives of moclobemide: Potential antidepressants with a dual mode of action Pessoa-Mahana H.; Gajardo, GR; Araya-Maturana, R; Carcamo, JK; Pessoa-Mahana, CD Article ISI SCOPUS SYNTHETIC COMMUNICATIONS (2004)
Improved selective reduction of 3-formylchromones using basic alumina and 2-propanol Araya-Maturana, R; Heredia-Moya, J; Pessoa-Mahana H.; Weiss-Lopez, B Article ISI SCOPUS SYNTHETIC COMMUNICATIONS (2003)
Effects of 4,4-dimethyl-5,8-dihydroxynaphtalene-1-one and 4,4-dimethyl-5,8-dihydroxytetralone derivatives on tumor cell respiration Araya-Maturana, R; Delgado-Castro, T; Garate, M.; Ferreira J.; Pavani, M.; Pessoa-Mahana H. Article ISI SCOPUS BIOORGANIC & MEDICINAL CHEMISTRY (2002)
Synthesis of N-(morpholinomethyl) benzamides as moclobemide analogs Pessoa-Mahana H.; Astudillo, CI; Araya-Maturana, R Article ISI SCOPUS SYNTHETIC COMMUNICATIONS (2002)
Conformational dynamics of substituted N-acetyl-N-phenylbenzylamines. H-1-DNMR and AM1-MO study Weiss-Lopez, BE; Jullian, C.; Saitz C.; Pessoa-Mahana H.; Valderrama J.; Araya-Maturana, R Article ISI BOLETIN DE LA SOCIEDAD CHILENA DE QUIMICA (2001)
Differential incorporation of L- and D-N-acyl-1-phenyl-d(5)-2-aminopropane in a cesium N-dodecanoyl-L-alaninate cholesteric nematic lyomesophase Weiss-Lopez, BE; Azocar, M; Montecinos R.; Araya-Maturana, R Article ISI LANGMUIR (2001)
Electron spin resonance studies and theoretical quantum calculations of free radicals generated from anthracenetrione by electrochemical and microsomal reduction Olea Azar C.; Mendizábal, F; Alarcón, J; Briones, R; Delgado-Castro, T; Araya-Maturana, R Article ISI SCOPUS SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2001)
Use of long-range C-H ((n)J n > 3) heteronuclear multiple bond connectivity in the assignment of the C-13 NMR spectra of complex organic molecules Araya-Maturana, R; Delgado-Castro, T; Cardona W.; Weiss-Lopez, BE Article ISI CURRENT ORGANIC CHEMISTRY (2001)
Average orientation and location of benzyl alcohol-d(5) and alkyl benzyl-d(5) ethers in anionic nematic lyotropic liquid crystals Weiss-Lopez, BE; Mino, G; Araya-Maturana, R; Tracey, AS Article ISI SCOPUS LANGMUIR (2000)
Complete assignment of the 13C NMR spectra of 4,4-dimethylanthracene-1,9,10(4H)-trione and the regioisomeric monomethyl derivatives Araya-Maturana, R; Cardona W.; Delgado-Castro, T; Jullian, C. Article SCOPUS MAGNETIC RESONANCE IN CHEMISTRY (2000)
Complete assignment of the C-13 NMR spectra of 4,4-dimethylanthracene-1,9,10(4H)-trione and the regioisomeric monomethyl derivatives Araya-Maturana, R; Cardona W.; Delgado-Castro, T; Jullian, C. Article ISI MAGNETIC RESONANCE IN CHEMISTRY (2000)
Regioselectivity in the Diels-Alder reaction of 8,8-dimethylnaphthalene-1,4,5(8<i>H</i>)-trione with 2,4-hexadien-1-ol Article ISI TETRAHEDRON (1999)
Average orientation of benzyl-d<sub>5</sub> alkyl ethers in cationic nematic lyomesophases Saldano, D Article ISI LANGMUIR (1997)
Highly stereoselective Aldol Reactions of Lithium Ester Enolates with (RS)-2-)p-Tolylsulfinyl)cyclohexanones García Ruano, José L.; Barros, David; Maestro, M. Carmen; Araya-Maturana, Ramiro; Fischer, Jean; Article JOURNAL OF ORGANIC CHEMISTRY (1996)
[1-(ETHOXYCARBONYL)-1-CYCLOPENTYL]TRIPHENYLPHOSPHONIUM BROMIDE, [(C6H5)(3)PC(C4H8)(COOC2H5)]BR BOYS, D Article ISI ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS (1995)
INFRARED-SPECTRA OF NITROSTYRENE DERIVATIVES Article ISI SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (1994)
A STUDY OF REACTIONS BETWEEN CARBOETHOXYMETHYLENETRIPHENYL-PHOSPHORANE AND ALKYL DIBROMIDES Article ISI PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS (1993)
STUDIES ON QUINONES .27. DIELS-ALDER REACTION OF 8,8-DIMETHYLNAPHTHALENE-1,4,5(8H)-TRIONE Article ISI JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (1993)
STUDIES ON QUINONES .21. REGIOSELECTIVE SYNTHESIS OF TETRACYCLIC QUINONES RELATED TO RABELOMYCIN GONZALEZ, MF Article ISI JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (1991)


Crystal structure of potassium antimony hexathiodiphosphate, KSbP2S6 Mahn A.; Navarro, G; Zapata, G Abstract ISI ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES (2005)


Incorporation mechanism of peptide TP1 into a membrane mimetic and into a model plasmatic membrane. 2H-NMR and Molecular Dynamics. FONDEF (1190382) Proyecto 2019-2022 Coinvestigador(a)
Synthesis and Pharmacological Evaluation of Mitochondria-Targeted Hydroquinone Derivatives with Antiplatelet Activity FONDECYT (1180427) Proyecto 2019-2021 Coinvestigador(a)
NEW MITOCHONDRIA-TARGETED ANTI-TUMOR COMPOUNDS=> SYNTHESIS OF ANTI-PROLIFERATIVE AND ANTI-MIGRATORY PHOSPHONIUM AND PYRIDINIUM SALTS DERIVED FROM ACYLPOLYPHENOLS FONDECYT (1180069) Proyecto 2018-2021 Inv. Principal
INCORPORATION, DISTRIBUTION AND DYNAMICS OF BENZOCAINE, PRILOCAINE AND DERIVATIVES IN THE BILAYER OF A NEW MEMBRANE MIMETIC MADE OF A NATURAL PHOSPHOLIPIDS MIXTURE. FONDECYT (1150138) Proyecto 2015-2019 Coinvestigador(a)
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF MITOCHONDRIA-TARGETED ANTITUMOR QUINONES AND HYDROQUINONES FONDECYT (1140753) Proyecto 2014-2018 Inv. Responsable
LIPOPHILIC CATIONS OF ESTERS OF ALKYLTRIPHENYLPHOSPHONIUM POLYHYDROXYBENZOATES AS MITOCHONDRIOTROPIC ANTINEOPLASTIC AGENTS. ANTITUMORAL ACTIVITY SPECTRA ON HUMAN TUMOUR CELLS FROM DIFFERENT TISSUES. FONDECYT (1130772) Proyecto 2013-2016 Coinvestigador(a)
ESTUDIO DE SINTESIS DE NUCLEOS QUINONICOS E HIDROQUINONICOS PARA LA ELABORACION DE LIBRERIAS DE COMPUESTOS ANTITUMORALES Y ANTIFUNGICOS FONDECYT (3120235) Proyecto 2011-2014 Inv. Patrocinante
REGIO- AND STEREO-SELECTIVE DIELS-ALDER REACTIONS IN THE SYNTHESIS OF CDC25B FOSFATASE INHIBITORS FONDECYT (1110176) Proyecto 2011-2014 Inv. Responsable
DISTRIBUTION, ORIENTATION, DYNAMICS AND REACTIVITY INDEXES OF BIOLOGICALL ACTIVE QUINONES AND HYDROQUINONES DISSOLVED IN MAGNETIC FIELD ORIENTED LIQUID CRYSTALS AND MEMBRANE MIMETICS.2H-NMR, MOLECULAR DYNAMICS (MD) AND MOLECULAR ORBIT FONDECYT (1095175) Proyecto 2009-2013 Coinvestigador(a)
ESTUDIOS DE REACTIVIDAD DIELS-ALDER DE DIENOLES QUIRALES Y AQUIRALES CON QUINONAS BICICLICAS 5-OXOSUSTITUIDAS, EVALUACION ANTITUMORAL Y ANTIPARASITARIA DE QUINONAS E HIDROQUINONAS TRI Y TETRACICLICAS FONDECYT (1071077) Proyecto 2007-2011 Inv. Responsable
CARACTERIZACION DE CRISTALES LIQUIDOS LIOTROPICOS NEMATICOS CON MEZCLAS HALUROS DE TETRADECILTRIMETIL AMONIO / DIMIRISTOILFOSOATIDILCOLINA (DMPC). RESONANCIA MAGNETICA NUCLEAR, APAGAMIENTO DE FLUORESCENCIA Y DINAMICA MOLECULAR FONDECYT (1050201) Proyecto 2005-2008 Coinvestigador(a)
ESTUDIO DE LA SELECTIVIDAD DIASTEREOFACIAL Y DE LA REGIOSELECTIVIDAD DE 1-SULFINIL-3, 5-DIEN-2-OLES QUIRALES EN REACCIONES DIELS-ALDER. FONDECYT (1030916) Proyecto 2003-2007 Inv. Responsable
ORIENTACION PROMEDIO Y DINAMICA REORIENTACIONAL DE ALCOHOLES BENCILICOS QUIRALES Y AQUIRALES Y SUS ETERES LINEALES DISUELTOS EN BICAPAS LIPIDAS. UN ESTUDIO 2H-RMN Y MODELACION MOLECULAR FONDECYT (1010211) Proyecto 2001-2005 Coinvestigador(a)
ESTUDIO DEL ROL DEL ENLACE DE PUENTE DE HIDROGENO INTERMOLECULAR EN LA REGIOQUIMICA DE REACCIONES DIELS-ALDER DE QUINONAS BICICLICAS 5-OXOSUSTITUIDAS FONDECYT (1000859) Proyecto 2000-2003 Inv. Responsable
DISENO RACIONAL DE INHIBIDORES Y SUSTRATOS SUBVERSIVOS DE LA TRIPANOTION REDUCTASA FONDECYT (1950301) Proyecto 1995-1998 Coinvestigador(a)


Regulation of mitochondrial function by hydroquinone derivatives as prevention of platelet activation Review ISI THROMBOSIS RESEARCH (2023)
An Emergent Role for Mitochondrial Bioenergetics in the Action of Snake Venom Toxins on Cancer Cells Vivas-Ruiz, Dan E. E. Review ISI FRONTIERS IN ONCOLOGY (2022)
Putting the brakes on tumorigenesis with snake venom toxins: New molecular insights for cancer drug discovery Review ISI SEMINARS IN CANCER BIOLOGY (2022)
Heterocyclic Curcumin Derivatives of Pharmacological Interest: Recent Progress Martinez-Cifuentes, M; Weiss-Lopez, B; Santos, LS; Araya-Maturana, R Review ISI CURRENT TOPICS IN MEDICINAL CHEMISTRY (2015)
Mitochondria: A Promising Target for Anticancer Alkaloids Urra, FA; Cordova-Delgado, M; Pessoa-Mahana H.; Ramirez-Rodriguez O.; Weiss-Lopez, B; Ferreira J.; Araya-Maturana, R Review ISI CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)
Very long-range correlations ((n)J(C,H) n > 3) in HMBC spectra Araya-Maturana, R; Pessoa-Mahana H.; Weiss-Lopez, B Review ISI NATURAL PRODUCT COMMUNICATIONS (2008)

Alejandra Ribera

Profesor Asistente A

Departamento de Producción Agropecuaria

Universidad de La Frontera

Temuco, Chile

Fernando Mendizabal

Full Professor

Chemistry

UNIVERSIDAD DE CHILE - FACULTAD DE CIENCIAS

Santiago, Chile

Juan Squella

Académico

Química Orgánica y Físico Química

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

Iván Palomo

Hematology Professor

Clinical Biochemistry and Immunohematology

UNIVERSIDAD DE TALCA

Talca, Chile

Angel Leiva

Full Professor

Physical Chemistry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Andres Vega

Director

Departamento de Química

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Joel Alderete

Full Professor

Universidad de Talca

Talca, Chile

ANDRES BARRIGA

Profesional

CEPEDEQ

UNIVERSIDAD DE CHILE

Santiago, Chile

Gerald Zapata

Profesor Asociado

Química Inorgánica y Analítica

Universidad de Chile

Santiago, Chile

Claudia Yáñez

académico

Química Orgánica y Físico Química

Universidad de Chile

Santiago, Chile

CLAUDIO SAITZ

Associate Prof.

Organic and Phisycal Chemistry

UNIVERSIDAD DE CHILE-FAC. CS. QUIMICAS Y FARMACEUTICAS

Santiago, Chile

ANTONIO GALDAMEZ

ASSOCIATE PROFESSOR

CHEMISTRY

DEPARTAMENTO DE QUÍMICA, FACULTAD DE CIENCIA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Jorge Ferreira

Director

Clinic and Molecular Farmacology

UNIVERSIDAD DE CHILE , FACULTAD DE MEDICINA, ICBM

Santiago, Chile

Juan Maya

Full Professor

Biomedical Sciences Institute

UNIVERSIDAD DE CHILE

Santiago, Chile

Mario Faúndez

Profesor Asistente

Farmacia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Marcelo Alarcón

Profesor

Bioquimica Clinica e Inmunahematologia

UNIVERSIDAD DE TALCA

Talca, Chile

Dante Miranda

Director de Extensión

Bioquímica y Biología Molecular

Universidad de Chile, Faculatd de Ciencias Químicas y Farmacéuticas

Santiago, Chile

claudio olea

Full Professor

Inorganica y Analitica

UNIVERSIDAD DE CHILE

Santiago, Chile

Carlos Pessoa

Profesor Titular

Departamento de Farmacia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

CAROLINA JULLIAN

Profesor Asociado

Quimica Organica y Fisicoquimica

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Milena Cotoras

Académica

Biologia

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

Patricia Perez

Full Professor

Ciencias Químicas

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

Pablo Jaque

Profesor Asociado

Química Orgánica y Fisicoquímica

Universidad de Chile

Santiago, Chile

Miguel Reyes

Full Professor

Facultad de Ciencias Médicas

UNIVERSIDAD DE SANTIAGO DE CHILE, FACULTAD DE CIENCIAS MÉDICAS, ESCUELA DE MEDICINA

Santiago, Chile

Julio Alarcón

Docente

Ciencias Básicas

UNIVERSIDAD DEL BÍO-BÍO

Chillan, Chile

LEONARDO SILVA

PROFESOR TITULAR

UNIVERSIDAD DE TALCA

TALCA, Chile

María Becker

Scientific Director, President

Research and Development

FUNDACIÓN CIENCIA Y TECNOLOGÍA PARA EL DESARROLLLO

Santiago, Chile

114

Ramiro Araya Maturana

Profesor Titular

Universidad de Talca

SantiaTalcago, Chile

Jorge Rodriguez

Professor

Department of Chemistry

UNIVERSIDAD METROPOLITANA DE CIENCIAS DE LA EDUCACIÓN

La Florida, Chile

Leonora Mendoza

Académico JC

Departamento de Química de los Materiales

Universidad de Santiago de Chile

Santiago, Chile

Javier Echeverría

Profesor Asociado e Investigador

Departamento de Ciencias del Ambiente

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago de Chile, Chile

Jorge Soto

Profesor Asistente

Departamento de Ciencias Quimicas

Universidad Andrés Bello

Viña del Mar, Chile

Rodrigo Pulgar

Profesor/Investigador asistente

INTA

UNIVERSIDAD DE CHILE - INSTITUTO DE NUTRICION Y TECNOLOGIA DE ALIMENTOS

Santiago, Chile

Angelica Fierro

Associate

Chemistry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Ricardo Salazar

PROFESOR ASOCIADO

QUÍMICA INORGÁNICA

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

Hernan Ahumada

Profesor Asistente

Universidad del Bio-Bio

Chillan, Chile

Eduardo Parra

ACADÉMICO - ESCUELA DE MEDICINA

MEDICINA

UNIVERSIDAD DE TARAPACA

Arica, Chile

Eduardo Fuentes

Profesor Titular

Universidad de Talca

Talca, Chile

Julio Caballero

Full Professor

Departamento de Bioinformática

Universidad de Talca

Talca, Chile

Renato Contreras

professor

Quimica

Universidad de Chile

Santiago, Chile

Wilson Cardona

Chemistry Department Area Coordinator

Chemistry

Universidad Andrés Bello

Talcahuano, Chile

Maximiliano Martínez

Profesor Asistente

Química Orgánica

Universidad de Concepción

Concepción, Chile

Sergio Wehinger

Académico Asociado

Bioquímica Clínica e Inmunohematología

UNIVERSIDAD DE TALCA

Talca, Chile

Michel Lapier

Académico

Química y Farmacia

Universidad de Valparaíso

Valparaíso, Chile

Claudio Valenzuela

CONFERENCIANTE

ESCUELA DE MEDICINA

Universidad de Talca

Talca, Chile

claudia vergara

PROFESOR ASISTENTE

Ciencias Básicas

Universidad Santo Tomás

TALCA, Chile

Jorge Toledo

Investigador

Centro de Investigacion Clinica Avanzada CICA

Universidad de Chile, Hospital Clinico Universidad de Chile

Santiago, Chile

Félix Urra

Profesor asistente

Facultad de Medicina, Instituto de Ciencias Biomédicas, Programa de Farmacología Molecular y Clínica

University of Chile

Santiago, Chile

Julio Rodríguez

Docente

Quimica Orgánica y Fisicoquímica

Universidad de Chile

Santiago, Chile

Evelyn Silva

Directora Ejecutiva

Vicerrectoria

Universidad Mayor de Chile

Santiago, Chile

Agustin Ibañez

DIRECTOR

INCYT

CABA, Argentina

JAIME MELLA

PROFESOR ADJUNTO

INSTITUTO DE QUIMICA Y BIOQUIMICA

UNIVERSIDAD DE VALPARAISO

VALPARAISO, Chile

John Amalraj

Associate Professor

Instituto de Quimica de Recursos Naturales

Universidad de Talca

Talca, Chile

Marcos Lorca

Coordinador Académico

Facultad de Ciencias de la Vida

Universidad Vina del Mar

Valparaíso, Chile

German Miño

Profesor

Universidad Andrés Bello

Santiago, Chile

Paul Silva

Profesor

Química Orgánica y Fisicoquímica

Universidad de Chile

Santiago, Chile

Jorge Vidal

Profesor Asistente

Química de los Materiales

Universidad de Santiago de Chile

Santiago, Chile

Iriux Almodóvar

Académico

Ciencias del Ambiente

Universidad de Santiago de Chile

Santiago, Chile

Sebastián Fuentes

Investigador Postdoctoral

Institulo de Ciencias Biomédicas - Instituto de investigación en Ciencias Odontológicas

Universidad de Chile

Santiago, Chile

Carlos Gallardo

Director Médico

Laboratorio Ximena Polanco

Santiago, Chile

catherin donoso

Postdoctorado

de Ciencias Exactas

Univesidad Andres Bello

Santiago, Chile

Christopher Cerda

Profesor

Universidad Bernardo O'Higgins

Santiago, Chile

Javiera Cortés

Investigador Postdoctoral

Instituto de Ingeniería Biológica y Médica

Pontificia Universidad Católica de Chile

Santiago, Chile

Hector Montecino

Investigador Postdoctoral

Centro de Estudios en Alimentos Procesados

Talca, Chile

Francisco Fuentes

Medico Ginecologo

Medico

Hospital de Curicó

Curicó, Chile

David Cabezas

Investigador

Centro de Investigaciones Nucleares para Aplicaciones en Salud y Biomedicina

Comisión Chilena de Energía Nuclear

Santiago, Chile

Ramiro Araya Maturana

Líneas de Investigación

Educación

Síntesis Orgánica, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1990

Química Orgánica, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1990

Experiencia Profesional

Professor Full Time

Article (113)

Abstract (1)

Proyecto (15)

Incorporation mechanism of peptide TP1 into a membrane mimetic and into a model plasmatic membrane. 2H-NMR and Molecular Dynamics.

Synthesis and Pharmacological Evaluation of Mitochondria-Targeted Hydroquinone Derivatives with Antiplatelet Activity

NEW MITOCHONDRIA-TARGETED ANTI-TUMOR COMPOUNDS=> SYNTHESIS OF ANTI-PROLIFERATIVE AND ANTI-MIGRATORY PHOSPHONIUM AND PYRIDINIUM SALTS DERIVED FROM ACYLPOLYPHENOLS

INCORPORATION, DISTRIBUTION AND DYNAMICS OF BENZOCAINE, PRILOCAINE AND DERIVATIVES IN THE BILAYER OF A NEW MEMBRANE MIMETIC MADE OF A NATURAL PHOSPHOLIPIDS MIXTURE.

SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF MITOCHONDRIA-TARGETED ANTITUMOR QUINONES AND HYDROQUINONES

LIPOPHILIC CATIONS OF ESTERS OF ALKYLTRIPHENYLPHOSPHONIUM POLYHYDROXYBENZOATES AS MITOCHONDRIOTROPIC ANTINEOPLASTIC AGENTS. ANTITUMORAL ACTIVITY SPECTRA ON HUMAN TUMOUR CELLS FROM DIFFERENT TISSUES.

ESTUDIO DE SINTESIS DE NUCLEOS QUINONICOS E HIDROQUINONICOS PARA LA ELABORACION DE LIBRERIAS DE COMPUESTOS ANTITUMORALES Y ANTIFUNGICOS

REGIO- AND STEREO-SELECTIVE DIELS-ALDER REACTIONS IN THE SYNTHESIS OF CDC25B FOSFATASE INHIBITORS

DISTRIBUTION, ORIENTATION, DYNAMICS AND REACTIVITY INDEXES OF BIOLOGICALL ACTIVE QUINONES AND HYDROQUINONES DISSOLVED IN MAGNETIC FIELD ORIENTED LIQUID CRYSTALS AND MEMBRANE MIMETICS.2H-NMR, MOLECULAR DYNAMICS (MD) AND MOLECULAR ORBIT

ESTUDIOS DE REACTIVIDAD DIELS-ALDER DE DIENOLES QUIRALES Y AQUIRALES CON QUINONAS BICICLICAS 5-OXOSUSTITUIDAS, EVALUACION ANTITUMORAL Y ANTIPARASITARIA DE QUINONAS E HIDROQUINONAS TRI Y TETRACICLICAS

CARACTERIZACION DE CRISTALES LIQUIDOS LIOTROPICOS NEMATICOS CON MEZCLAS HALUROS DE TETRADECILTRIMETIL AMONIO / DIMIRISTOILFOSOATIDILCOLINA (DMPC). RESONANCIA MAGNETICA NUCLEAR, APAGAMIENTO DE FLUORESCENCIA Y DINAMICA MOLECULAR

ESTUDIO DE LA SELECTIVIDAD DIASTEREOFACIAL Y DE LA REGIOSELECTIVIDAD DE 1-SULFINIL-3, 5-DIEN-2-OLES QUIRALES EN REACCIONES DIELS-ALDER.

ORIENTACION PROMEDIO Y DINAMICA REORIENTACIONAL DE ALCOHOLES BENCILICOS QUIRALES Y AQUIRALES Y SUS ETERES LINEALES DISUELTOS EN BICAPAS LIPIDAS. UN ESTUDIO 2H-RMN Y MODELACION MOLECULAR

ESTUDIO DEL ROL DEL ENLACE DE PUENTE DE HIDROGENO INTERMOLECULAR EN LA REGIOQUIMICA DE REACCIONES DIELS-ALDER DE QUINONAS BICICLICAS 5-OXOSUSTITUIDAS

DISENO RACIONAL DE INHIBIDORES Y SUSTRATOS SUBVERSIVOS DE LA TRIPANOTION REDUCTASA

Review (6)