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Maria Cecilia Vial Cox

Associate Professor/Profesor Asociado

UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

Host response to infection/Respuesta a Infección Hantavirus Coronavirus Genomics/Genómica

Cellular and Molecular Biology, Pontificia Universidad Católica de Chile. Chile, 2008

post doctoral fellow Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile

2008 - 2009
Profesor Asistente Full Time

Universidad Del Desarrollo

Chile

2010 - 2018
Profesor Asociado Full Time

UNIVERSIDAD DEL DESARROLLO

Facultad de Medicina

Santiago, Chile

2018 - At present

Post doctoral fellow Full Time

Pontificia Universidad Católica de Chile

Chile

2008 - 2009
Profesor Asistente Full Time

Universidad del Desarrollo

Chile

2010 - 2018
Profesor Asociado Full Time

Universidad del Desarrollo

Santiago, Chile

2018 - At present

Undergraduate Thesis:

- Undergradute thesis tutor Daniela Budge, Francisca Velasquez (Medical Technologist UDD Sept 2017- Dec 2018) “OPTIMIZACIÓN DEL PROCESAMIENTO DE MUESTRAS DE SANGRE PARA LA OBTENCIÓN EFICIENTE DE CÉLULAS MONONUCLEARES Y ARN”
- Undergraduate thesis tutor Daniela Vidal and Gabriela Cáceres (Medical Technologist UMayor Agu 2014-Dec 2015) “ VIRUS HANTA: EFECTO DE LA INFECCIÓN POR VIRUS ANDES EN LA EXPRESIÓN GÉNICA DE CTNNA Y HSPA9 IN VITRO”

Graduate Thesis:
- Gradute Thesis tutor Grazielle Esteves Ribeiro (Doctorado Ciencias e Innovación en Medicina March 2017- ongoing)

Otras Actividades Académicas:
• Tutoring of two medicine students in a laboratory internship (PONT UDD) (May/2019-Nov/2019)
• Hemorrhagic fever class to Medicine undergrad students (October 2019)
• Professor in PhD course: Genética y Genómica Aplicadas a la Medicina de Precisión at Universidad del Desarrollo (2nd Semester, 2018)
• Professor in PhD course: Genética y Genómica Aplicadas a la Medicina de Precisión at Universidad del Desarrollo (2nd Semester, 2018)
• Professor in PhD course: Genetics and Genomics for PhD students at Universidad del Desarrollo (2nd Semester, 2017)
• Professor in undergraduate course Biología Molecular y Genética (1st semester 2017)
• Professor in undergraduate course Biología Molecular y Genética (2nd semester 2016)
• Professor in PhD course: Genetics and Genomics for PhD students at Universidad del Desarrollo (2nd Semester, 2016)
• Coordinator Professor of PhD course: Genetics and Genomics for PhD students at Universidad del Desarrollo (2nd Semester, 2014)
• Member of the PhD Comitee for the "Doctorado en Ciencias Médicas", Facultad de Medicina, Universidad del Desarrollo (dec 2014-nov 2018)
• Tutoring of two medicine students in a laboratory internship (Mar/2012-Nov/2012)
• Tutoring of an exchange student from Stanford University in a laboratory internship (10/2012-11/2012)
• COURSE Unidad de Investigación 2011, Universidad del Desarrollo, tutor of the project: Validation of a genetic test for the diagnosis of lactose intolerance in chilean pediatric population
• COURSE Unidad de Investigación 2010, Universidad del Desarrollo, tutor of the project: Osteoclast differentiation for studying Osteogenesis Imperfecta

• Twitter account for information on Hantavirus for general Public @virushanta

• Instagram Account for information on Hantavirus for general Public @virushantachile

• WORKSHOP ON HANTAVIRUS RESEARCH, TRANSLATION AND PUBLIC HEALTH, Monday 11th of March Auditorium Fundación Ciencia & Vida, talk: “Understanding Hantavirus Cardiopulmonary Syndrome"

• 24 Horas (Television) Jueves 07 de Marzo del 2019 del 2019, La Mañana Informativa. Interview: Cecilia Vial, primer caso de contagio de virus Hanta en la región Metropolitana
• https://www.youtube.com/watch?v=Oq6hls7piUY

• Diario el Sur, 16 Enero 2019, Interview: Cecilia Vial, hantavirus: genetics can explain immune response to the virus

• Radio Universo, jueves 10 de enero 2019, Interview: Cecilia Vial, Investigadora Facultad de Medicina Clínica Alemana UDD, talks about Epuyen outbrake transmission and prevention of hantavirus

• 24 Horas (Television) Miércoles 09 de Enero del 2019, La Mañana Informativa. Interview: Cecilia Vial, Investigadora Facultad de Medicina Clínica Alemana UDD, talks about hantavirus transmission and prevention.
• https://www.youtube.com/watch?v=ByNTK3o30rU

• Interview a Cecilia Vial, Académica Medicina UDD, COntrafactual, 28 Diciembre 2018
• http://contrafactual.cl/2018/12/26/entrevista-a-cecilia-vial-academica-udd-la-medicina-nos-ha-tratado-por-muchos-anos-como-promedios-pero-efectivamente-como-tu-dices-somos-geneticamente-distintos-por-lo-tanto-no-siempre/

• Mini-Symposium: “Novel insights into hantavirus hosts; epidemics and infection”; 2017. Fundación Ciencia y Vida; Santiago; Chile. Talk: hantavirus quasispecies


Seroprevalence of Natural and Acquired Immunity against the SARS-CoV-2 Virus in a Population Cohort from Two Chilean Cities, 2020-2022 Nunez-Franz, Loreto; Ramirez-Santana, Muriel; Rubilar, Paola; ; Vial, Cecilia; Apablaza, Mauricio;; Gonzalez, Claudia; Said, Macarena; Olivares, Kathya; Cortes, Lina Jimena; Hormazabal, Juan; Canales, Luis; Vial, Pablo; Icaza, Gloria;; Quezada-Gaete, Ruben; Aguilera, Ximena Article ISI VIRUSES-BASEL (2023)
Deep immunophenotyping reveals biomarkers of multisystemic inflammatory syndrome in children in a Latin American cohort Rey-Jurado, Emma; Espinosa, Yazmin; Astudillo, Camila; Jimena Cortes, Lina; Hormazabal, Juan; Noguera, Loreani P.; Cofre, Fernanda; Pinera, Cecilia; Gonzalez, Ricardo; Bataszew, Alexander; Munoz Venturelli, Paula; Benadof, Dona; Alvarez, Patricia; Acevedo, Valeria; Vial, Pablo; ; Vial, Cecilia; Poli, M. Cecilia Article ISI JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2022)
Evaluation of the Immune Response Induced by CoronaVac 28-Day Schedule Vaccination in a Healthy Population Group Escobar, Alejandro; Reyes-Lopez, Felipe E.; Acevedo, Monica L.; Alonso-Palomares, Luis; Valiente-Echeverria, Fernando; Soto-Rifo, Ricardo; Portillo, Hugo; Gatica, Jimena; Flores, Ivan; Nova-Lamperti, Estefania; Barrera-Avalos, Carlos; Bono, Maria Rosa; Vargas, Leonardo; Simon, Valeska; Leiva-Salcedo, Elias; ; Vial, Cecilia; Hormazabal, Juan; Cortes, Lina Jimena; Valdes, Daniel; Sandino, Ana M.; Imarai, Monica; Acuna-Castillo, Claudio Article ISI FRONTIERS IN IMMUNOLOGY (2022)
Immunization and SARS-CoV-2 Antibody Seroprevalence in a Country with High Vaccination Coverage: Lessons from Chile Aguilera, Ximena; Gonzalez, Claudia; Apablaza, Mauricio;; Rubilar, Paola; Icaza, Gloria;; Ramirez-Santana, Muriel; Perez, Claudia; Cortes, Lina Jimena; Nunez-Franz, Loreto; Quezada-Gaete, Ruben; Castillo-Laborde, Carla; Correa, Juan; Said, Macarena; Hormazabal, Juan; ; Vial, Cecilia; Vial, Pablo Article ISI VACCINES (2022)
Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19 Sacco, Keith; Castagnoli, Riccardo; Vakkilainen, Svetlana; Liu, Can; Delmonte, Ottavia M.; Oguz, Cihan; Kaplan, Ian M.; Alehashemi, Sara; Burbelo, Peter D.; Bhuyan, Farzana; de Jesus, Adriana A.; Dobbs, Kerry; Rosen, Lindsey B.; Cheng, Aristine; Shaw, Elana; Vakkilainen, Mikko S.; Pala, Francesca; Lack, Justin; Zhang, Yu; Fink, Danielle L.; Oikonomou, Vasileios; Snow, Andrew L.; Dalgard, Clifton L.; Chen, Jinguo; Sellers, Brian A.; Sanchez, Gina A. Montealegre; Barron, Karyl; Rey-Jurado, Emma; ; Vial, Cecilia; Poli, Maria Cecilia; Licari, Amelia; Montagna, Daniela; Marseglia, Gian Luigi; Licciardi, Francesco; Ramenghi, Ugo; Discepolo, Valentina; Lo Vecchio, Andrea; Guarino, Alfredo; Eisenstein, Eli M.; Imberti, Luisa; Sottini, Alessandra; Biondi, Andrea; Mato, Sayonara; Gerstbacher, Dana; Truong, Meng; Stack, Michael A.; Magliocco, Mary; Bosticardo, Marita; Kawai, Tomoki; Danielson, Jeffrey J.; Hulett, Tyler; Askenazi, Manor; Hu, Shaohui; Cohen, Jeffrey, I; Su, Helen C.; Kuhns, Douglas B.; Lionakis, Michail S.; Snyder, Thomas M.; Holland, Steven M.; Goldbach-Mansky, Raphaela; Tsang, John S.; Notarangelo, Luigi D.; NIAID Immune Response Covid Grp; Chile MIS-C Grp; Pavia Pediat COVID-19 Grp Article ISI NATURE MEDICINE (2022)
SARS-CoV-2 Neutralizing Antibodies in Chile after a Vaccination Campaign with Five Different Schemes Aguilera, Ximena; Hormazabal, Juan; ; Vial, Cecilia; Jimena Cortes, Lina; Gonzalez, Claudia; Rubilar, Paola; Apablaza, Mauricio;; Ramirez-Santana, Muriel; Icaza, Gloria;; Nunez-Franz, Loreto; Castillo-Laborde, Carla; Ramirez-Riffo, Carolina; Perez, Claudia; Quezada-Gate, Ruben; Said, Macarena; Vial, Pablo Article ISI VACCINES (2022)
Seroprevalence, spatial distribution, and social determinants of SARS-CoV-2 in three urban centers of Chile Vial, Pablo; Gonzalez, Claudia; Icaza, Gloria;; Ramirez-Santana, Muriel; Quezada-Gaete, Ruben; Nunez-Franz, Loreto; Apablaza, Mauricio;; ; Vial, Cecilia; Rubilar, Paola; Correa, Juan; Perez, Claudia; Florea, Andrei; Guzman, Eugenio; Lavin, Maria-Estela; Concha, Paula; Najera, Manuel; Aguilera, Ximena Article ISI BMC INFECTIOUS DISEASES (2022)
An international, interlaboratory ring trial confirms the feasibility of an extraction-less “direct” RT-qPCR method for reliable detection of SARS-CoV-2 RNA in clinical samples Margaret G. Mills ,Emily Bruce ,Meei-Li Huang,Jessica W. Crothers,Ollivier Hyrien,Christopher A. L. Oura,Lemar Blake,Arianne Brown Jordan,Susan Hester,Leah Wehmas,Bernard Mari,Pascal Barby,Caroline Lacoux,Julien Fassy,Pablo Vial,Cecilia Vial,Jose R. W. Ma Article (2021)
Novel Vector of Scrub Typhus in Sub-Antarctic Chile: Evidence From Human Exposure Weitzel, Thomas; Carolina Silva-de la Fuente, Maria; Martinez-Valdebenito, Constanza; Stekolnikov, Alexandr A.; Perez, Caricia; Perez, Ruth; ; Vial, Cecilia; Abarca, Katia; Acosta-Jamett, Gerardo Article ISI CLINICAL INFECTIOUS DISEASES (2021)
Proteinuria in Hantavirus Cardiopulmonary Syndrome: A Frequent Finding Linked To Mortality Espinoza, Mauricio; Graf, Jeronimo; Mertz, Gregory; Ferres, Marcela; Calvo, Mario; ; Vial, Cecilia; Vial, Pablo A.; Hantavirus Study Grp Article ISI INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)
Targeted high volume hemofiltration could avoid extracorporeal membrane oxygenation in some patients with severe Hantavirus cardiopulmonary syndrome Lopez, Rene; Perez-Araos, Rodrigo; Salazar, Alvaro; Espinoza, Mauricio; ; Vial, Cecilia; Cuiza, Analia; Vial, Pablo A.; Graf, Jeronimo Article ISI JOURNAL OF MEDICAL VIROLOGY (2021)
Comparison of VSV Pseudovirus and Focus Reduction Neutralization Assays for Measurement of Anti-Andes orthohantavirusNeutralizing Antibodies in Patient Samples ; Vial, Cecilia; Whitaker, Annalis; Wilhelm, Jan; Ovalle, Jimena; Perez, Ruth; Valdivieso, Francisca; Ferres, Marcela; Martinez-Valdebenito, Constanza; Eisenhauer, Philip; Mertz, Gregory J.; Hooper, Jay W.; Botten, Jason W.; Vial, Pablo A. Article ISI FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)
Impact of arsenic exposure on clinicopathological characteristics of bladder cancer: A comparative study between patients from an arsenic-exposed region and nonexposed reference sites Fernandez, Mario I.; Valdebenito, Patricio; Delgado, Iris; Segebre, Jorge; Chaparro, Eduardo; Fuentealba, David; Castillo, Martin; ; Vial, Cecilia; Barroso, Juan P.; Ziegler, Annemarie; Bustamante, Alberto Article ISI SCOPUS UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2020)
Mother-to-Child Transmission of Andes Virus through Breast Milk, Chile1 Ferrés, Marcela; Martínez-Valdebenito, Constanza; Angulo, Jenniffer; Henríquez, Carolina; Vera-Otárola, Jorge; Vergara, María José; Pérez, Javier; Fernández, Jorge; Sotomayor, Viviana; Valdés, María Francisca; González-Candia, Diego; Tischler, Nicole D.; ; Vial, Cecilia; Vial, Pablo; Mertz, Gregory; Le Corre, Nicole Article EMERGING INFECTIOUS DISEASES (2020)
NPC1 as a Modulator of Disease Severity and Viral Entry of Sars-CoV-2 ; Vial, Cecilia; Calderón, Juan Francisco; Klein, Andrés D. Article Current Molecular Medicine (2020)
A 19 Year Analysis of Small Mammals Associated with Human Hantavirus Cases in Chile Torres-Perez, Fernando; Eduardo Palma, R.; Boric-Bargetto, Dusan; ; Vial, Cecilia; Ferres, Marcela; Vial, Pablo A.; Martinez-Valdebenito, Constanza; Pavletic, Carlos; Parra, Alonso; Marquet, Pablo A.; Mertz, Gregory J. Article ISI SCOPUS VIRUSES-BASEL (2019)
A Single-Nucleotide Polymorphism of (V3) Integrin Is Associated with the Andes Virus Infection Susceptibility Martinez-Valdebenito, C; Angulo, J; Le Corre, N; Marco, C; Vial, C; Miquel, JF; Cerda, J; Mertz, G; Vial, P; Lopez-Lastra, M; Ferres, M Article ISI SCOPUS VIRUSES-BASEL (2019)
Adaptation to Extreme Environments in an Admixed Human Population from the Atacama Desert Vicuna, Lucas; Fernandez, Mario I.; ; Vial, Cecilia; Valdebenito, Patricio; Chaparro, Eduardo; Espinoza, Karena; Ziegler, Annemarie; Bustamante, Alberto; Eyheramendy, Susana Article ISI SCOPUS GENOME BIOLOGY AND EVOLUTION (2019)
Deletions in Genes Participating in Innate Immune Response Modify the Clinical Course of Andes Orthohantavirus Infection Esteves Ribeiro, Grazielle; Edgardo Leon, Luis; Perez, Ruth; Cuiza, Analia; Agustin Vial, Pablo; Ferres, Marcela; Mertz, Gregory J.; ; Vial, Cecilia Article ISI SCOPUS VIRUSES-BASEL (2019)
Hemodynamic and Pulmonary Permeability Characterization of Hantavirus Cardiopulmonary Syndrome by Transpulmonary Thermodilution Lopez, Rene; Perez-Araos, Rodrigo; Salazar, Alvaro; Ulloa, Ana L.; ; Vial, Cecilia; Vial, Pablo A.; Graf, Jeronimo Article ISI SCOPUS VIRUSES-BASEL (2019)
Platelet Count in Patients with Mild Disease at Admission is Associated with Progression to Severe Hantavirus Cardiopulmonary Syndrome Lopez, Rene; ; Vial, Cecilia; Graf, Jeronimo; Calvo, Mario; Ferres, Marcela; Mertz, Gregory; Cuiza, Analia; Agueero, Begonia; Aguilera, Dante; Araya, Diego; Pailamilla, Ignacia; Paratori, Flavia; Torres-Torres, Victor; Vial, Pablo A.; Abarca, Juan; Miguel Noriega, Luis; Valdivieso, Francisca; Delgado, Iris; Martinez, Constanza; Carlos Chamorro, Juan; Hernandez, Jury; Pino, Marcelo; Vega, Ivonne; Otarola, Irisol; Ortega, Carlos; Daube, Elizabeth; Castillo, Constanza; Mardones, Jovita; Sanhueza, Ligia; Inostroza, Jaime; Donoso, Solange; Navarrete, Maritza; Araneda, Andres; Aguilera, Teresa; Osorio, Carola; Yobanolo, Veronica; Scholz, Luis; Riquelme, Raul; Riquelme, Mauricio; Munoz, Miriam; Hantavirus Study Grp Chile Article ISI SCOPUS VIRUSES-BASEL (2019)
Partial microduplication in the histone acetyltransferase complex member KANSL1 is associated with congenital heart defects in 22q11.2 microdeletion syndrome patients León L.E.; Benavides F.; Espinoza K.; Vial C.; Alvarez P.; Palomares M.; Lay-Son G.; Miranda M.; Repetto G.M. Article ISI SCOPUS SCIENTIFIC REPORTS (2017)
Partial microduplication in the histone acetyltransferase complex member KANSL1 is associated with congenital heart defects in 22q11.2 microdeletion syndrome patients León L.E., Benavides F.; Espinoza K., Vial C.; Alvarez P., Palomares M.; Lay-Son G., Miranda M. Article Scientific Reports (2017)
Accuracy of a Genetic Test for the Diagnosis of Hypolactasia in Chilean Children: Comparison With the Breath Test Alliende F.; Vial, C; Espinoza, K; Schnettle D.; Romero, V; Miquel I.; Arancibia M.E.; Rios G.; Rodríguez L.; Quesada S.; Lucero, Y; Repetto G.M. Article ISI SCOPUS JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2016)
Molecular method for the detection of Andes hantavirus infection: validation for clinical diagnostics Vial, C; Martinez-Valdebenito, C; Ríos S; Martinez, J.; Vial, PA; Ferrés M.; Rivera, JC; Perez, R; Valdivieso, F Article ISI SCOPUS DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2016)
A non-randomized multicentre trial of human immune plasma for treatment of hantavirus cardiopulmonary syndrome caused by Andes virus Vial, PA; Valdivieso, F; Calvo M.; Rioseco, ML; Riquelme R.; Araneda, A.; Tomicic V.; Graf J.; Paredes, L.; Florenzano M.; Bidart T.; Cuiza, A; Marco C.; Hjelle, B; Ye, CY; Hanfelt-Goade, D; Vial, C; Rivera, JC; Delgado, I; Mertz, GJ Article ISI SCOPUS Antiviral Therapy (2015)
Chromosomal microarrays testing in children with developmental disabilities and congenital anomalies Lay-Son, G; Espinoza, K; Vial, C; Rivera, JC; Guzman, ML; Repetto, GM Article ISI SCOPUS Jornal de Pediatria (2015)
Genetic structure characterization of Chileans reflects historical immigration patterns Eyheramendy, S; Martinez, FI; Manevy, F; Vial, C; Repetto, GM Article ISI SCOPUS NATURE COMMUNICATIONS (2015)
Case fatality rate and associated factors in patients with 22q11 microdeletion syndrome: a retrospective cohort study Repetto, GM; Guzman, ML; Delgado, I; Loyola, H; Palomares, M; Lay-Son, G; Vial, C; Benavides F.; Espinoza, K; Alvarez, P Article ISI SCOPUS BMJ OPEN (2014)
High-Dose Intravenous Methylprednisolone for Hantavirus Cardiopulmonary Syndrome in Chile: A Double-Blind, Randomized Controlled Clinical Trial Vial, PA; Valdivieso, F; Ferrés M.; Riquelme R.; Rioseco, ML; Calvo M.; Castillo C.; Díaz R; Scholz, L; Cuiza, A; Belmar, E; Hernandez C.; Martinez, J.; Lee, SJ; Mertz, GJ Article ISI SCOPUS Clinical Infectious Diseases (2013)
Comparative performance of symptoms questionnaire, hydrogen test and genetic test for lactose intolerance Rollan, A; Vial, C; Quesada S.; Espinoza, K; Hatton, M; Puga, A; Repetto, G Article ISI REVISTA MEDICA DE CHILE (2012)
Diagnóstico de intolerancia a la lactosa en adultos: rendimiento comparativo de la clínica, test de hidrógeno espirado y test genético Rollan, A; Vial, C; Quesada S.; Espinoza, K; Hatton, M; Puga, A; Repetto, G Article SCIELO SCOPUS REVISTA MEDICA DE CHILE (2012)
Connective tissue growth factor induction by lysophosphatidic acid requires transactivation of transforming growth factor type beta receptors and the JNK pathway Cabello-Verrugio, C; Córdova G.; Vial, C; Zuñiga LM; Brandan, E. Article ISI SCOPUS Cellular Signalling (2011)
Decorin Interacts with Connective Tissue Growth Factor (CTGF)/CCN2 by LRR12 Inhibiting Its Biological Activity Vial, C; Gutierrez J.; Santander C.; cabrera, D; Brandan, E. Article ISI SCOPUS Journal of Biological Chemistry (2011)
Matrix Metalloproteinase-2-deficient Fibroblasts Exhibit an Alteration in the Fibrotic Response to Connective Tissue Growth Factor/CCN2 because of an Increase in the Levels of Endogenous Fibronectin Droppelmann, CA; Gutierrez J.; Vial, C; Brandan, E. Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
CTGF Inhibits BMP-7 Signaling in Diabetic Nephropathy Nguyen TQ; Roestenberg P; van Nieuwenhoven FA; Bovenschen N; Li Z.; Xu, L; Oliver N.; Aten J; Joles JA; Vial, C; Brandan, E.; Lyons KM; Goldschmeding, R Article ISI SCOPUS JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)
Skeletal muscle cells express the profibrotic cytokine connective tissue growth factor (CTGF/CCN2), which induces their dedifferentiation Vial, C; Zuñiga LM; Cabello-Verrugio, C; Canon, P.; Fadic, R; Brandan, E. Article ISI SCOPUS JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Constitutively activated dystrophic muscle fibroblasts show a paradoxical response to TGF-beta and CTGF/CCN2 Mezzano, Valeria; Cabrera, Daniel; ; Vial, Cecilia; Brandan, Enrique Article ISI Journal of Cell Communication and Signaling (2007)
1. Autoantibodies against proteins previously associated with autoimmunity in adult and pediatric patients with COVID-19 and children with MIS-C Peter Burbelo, Riccardo Castagnoli, Chisato Shimizu, Ottavia Maria Delmonte, Kerry Dobbs, Valentina Discepolo, Andrea Lo Vecchio, Alfredo Guarino, Francesco Licciardi, UGO RAMENGHI, Emma Rey, Maria Vial, Gian Luigi Marseglia, Amelia Licari, Daniela Montag Article FRONTIERS IN IMMUNOLOGY
Case fatality rate and associated factors in 22q11 microdeletion syndrome patients: A retrospective cohort study Repetto, GM; Guzman, ML; Delgado, I; Loyola, H; Palomares, M; Lay-Son, G; Vial, C; Benavides F.; Espinoza, K; Alvarez, P Article BMJ OPEN
Nonrandomized multicenter trial of human immune plasma for treatment of hantavirus cardiopulmonary syndrome by ANDV Vial, Pablo; Valdivieso, Francisca; Calvo, Mario; Rioseco, Maria Luisa; Riquelme, Raul; Araneda, Andres; Tomicic, Vinko; Graf, Jeronimo; Paredes, Laura; Florenzano, Matias; Bidart, Teresa; Cuiza, Analia; Marco, Claudia; Hjelle, Brian; Ye, Chunyan; Hanfelt-Goade, DIane; ; Vial, Cecilia; Rivera, Juan Carlos; Delgado, Iris; Mertz, Gregory Article ANTIVIRAL THERAPY
Person-to-Person Household and Nosocomial Transmission of Andes Hantavirus, Southern Chile, 2011 Martinez-Valdebenito, Constanza; Calvo, Mario; ; Vial, Cecilia; Mansilla, Rita; Marco, Claudia; Palma, Eduardo; Vial, Pablo; Valdivieso, Francisca; Mertz, Gregory; Ferres, Marcela Article EMERGING INFECTIOUS DISEASES


Detección de anticuerpos contra SARS-CoV-2 : IgG mediante ELISA y neutralizantes en una plataforma de Bioseguridad tipo 2. VIAL, MARIA CECILIA Proyecto Colabs: UDD CECILIA VIAL, CECILIA POLI (SENIOR ADV PABLO VIAL) – UC NICOLE LECORRE, CONSTANZA MARTINEZ (SENIOR ADV MARCELA FERRES) UCHILE FERNANDO VALIENTE, RICARDO SOTO-RIFFO - CAS MIRENTXU IRURETAGOYENA, LORENA PORTES - MERKEN JAVIER GUERRERO (2020)
Mecanismos inmunológicos protectores y biomarcadores de respuesta inmune en COVID19: Identificación de dianas terapéuticas para la recomendación de terapias inmunomoduladoras de uso precoz. VIAL, MARIA CECILIA; Poli, Cecilia Proyecto (2020)
Unraveling the differences between mild and severe hantavirus infected patients: delineating mechanisms to propose novel therapeutic approaches. VIAL, MARIA CECILIA Proyecto Co-invesitgadores Pablo Vial, Marcela Ferres, Flavio Carrión, Luis Leon (2020)
Collaborative network on immunopathogenesis of Hantavirus Infection PCI (180195) Proyecto 2019-2020 Inv. Principal
PROMETHEUS=> A PLATFORM FOR RAPID DEVELOPMENT OF HUMAN ANTIBODY-BASED THERAPEUTICS AND PROPHYLACTICS AGAINST EMERGING VIRAL THREATS NIH (U19AI142777) Proyecto 2019-2023 Coinvestigador(a)
Ecology and Evolutionary Epidemiology of Andes Hantavirus and its Associated Rodent Reservoir FONDECYT (1171280) Proyecto 2017-2021 Coinvestigador(a)
Understanding host response to ANDV infection, immunological and transcriptomics approach FONDECYT (1161447) Proyecto 2016-2020 Inv. Principal
Understanding Host Response to ANDV infection, immunological and transcriptomics approach VIAL, MARIA CECILIA; Vial C, Pablo A; Leon, Luis; Carrion, Flavio R.; Ferres, Marcela Proyecto (2016)
VIRAL QUASISPECIES, ORAL HOST IMMUNE AND CONSTITUTIVE FACTORS IN ANDES VIRUS INFECTED CASES AND EXPOSED SUBJECTS=> ROLE IN INFECTION AND TRANSMISSION. FONDECYT (1161197) Proyecto 2016-2020 Coinvestigador(a)
Anomalías congénitas y trastornos del desarrollo=> Evaluación de costo-efectividad de las nuevas herramientas diagnósticas FONIS (SA13I20321) Proyecto 2014-2016 Coinvestigador(a)
EXPLORANDO LA SENSIBILIDAD AL ESTRES EN INFANTES=> UN ESTUDIO GENETICO, PSICOBIOLOGICO Y VINCULAR FONDECYT (1140265) Proyecto 2014-2017 Coinvestigador(a)
GENETIC MODIFIERS OF THE CARDIOVASCULAR PHENOTYPE OF CHROMOSOME 22Q11 MICRODELETION SYNDROME=> NEXT-GENERATION SEQUENCING OF CANDIDATE REGIONS IDENTIFIED BY GENOME-WIDE ASSOCIATION ANALYSIS FONDECYT (1130392) Proyecto 2013-2017 Coinvestigador(a)
GENETIC VARIANTS RELATED TO PRESENCE OF BLADDER UROTHELIAL CARCINOMA IN A HIGH-RISK, ARSENIC-EXPOSED POPULATION IN NORTHERN CHILE (ANTOFAGASTA)=> A GENOME-WIDE ASSOCIATION STUDY. FONDECYT (11120987) Proyecto 2012-2015 Coinvestigador(a)
Host Genetic Factors and Severity of Andes hantavirus Infection=> a Genome Wide Association Study FONDECYT (11110397) Proyecto 2011-2014 Inv. Principal
Andes VIrus Transmission and Pathogenesis in Chile NIH (U01AI04545) Proyecto 2010-2015 Coinvestigador(a)
GENETIC MODIFIERS OF THE 22Q11 MICRODELETION SYNDROME=> A GENOME-WIDE ASSOCIATION STUDY FONDECYT (1100131) Proyecto 2010-2013 Coinvestigador(a)
Center of Aging and regeneration (CARE) FONDAP (12/2007) Proyecto 2009-2009 Postdoctorado
center for cellular regulation and pathology FONDAP FONDAP (1398001) Proyecto 2000-2009 Tesista


Meeting report: Eleventh International Conference on Hantaviruses Clement, J.; Ahlm C.; AvÅ¡i?-Å½upanc T.; Botten J.; Chandran K.; Jonsson C.B.; Kariwa H.; KlingstrÃ¶m J.; Klempa B.; KrÃ¼ger D.H.; Leirs H.; Li D.; Liang M.; Markoti? A.; Papa A.; Schmaljohn C.S.; Tischler, N. D.; Ulrich R.G.; Vaheri A.; Vial C.; Yanagihara R.; Maes P. Review ISI SCOPUS (2020)
Novel regulatory mechanisms for the proteoglycans decorin and biglycan during muscle formation and muscular dystrophy Brandan, E.; Cabello-Verrugio, C; Vial, C Review ISI MATRIX BIOLOGY (2008)

Maria Vial

Associate Professor/Profesor Asociado

Instituto de Ciencias e Innovación de Medicina

UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

Enrique Brandan

Profesor Titular

Biología Celular y Molecular

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Pablo Vial

Professor

School of Medicine

ICIM/UNIVERSIDAD DEL DESARROLLO - CLÍNICA ALEMANA

Santiago, Chile

Marcela Ferres

Head of Department

Pediatric Infectious Diseases and Immunology

Pontificia Universidad Católica de Chile

Santiago, Chile

Karena Espinoza

Directora

Centro Asistencial Docente e Investigación

Universidad de Magallanes

Punta Arenas, Chile

LINA CORTES

Investigadora Postdoctoral

Facultad de Medicina

Universidad del Desarrollo

Santiago, Chile

Claudio Cabello

Full Professor

Ciencias Biologicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Muriel Ramirez

Profesor Titular

Salud Pública

Universidad Catolica del Norte

Coquimbo, Chile

MARIO CALVO

Profesor Asociado

Instituto de Medicina

UNIVERSIDAD AUSTRAL DE CHILE

VALDIVIA, Chile

Juan Hormazabal

Investigador Postdoctoral

Facultad De Medicina

Universidad del Desarrollo

Santiago, Chile

Mauricio Apablaza

Research Director

Gobierno

Universidad del Desarrollo

Santiago, Chile

Constanza Martinez

Investigador asistente

Enfermedades infecciosas e inmunologia pediatrica

Pontificia Universidad Católica de Chile

Santiago, Chile

Maria Nunez

ACADEMICA DEPTO. SALUD PÚBLICA

SALUD PUBLICA

UNIVERSIDAD DE TALCA

Talca, Chile

Juan Rivera

Investigador

Instituto Milenio de Inmunología e Inmunoterapia

Santiago, Chile

Orozimba Delgado

Profesor Asociado

Facultad de Medicina Clinica Alemana Universidad del Desarrollo

UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

Guillermo Lay-Son

PROFESOR ASISTENTE

CENTRO DE GENÉTICA Y GENÓMICA

UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

Daniel Cabrera

Investigador Adjunto

Gastroenterología

Pontificia Universidad Catolica de Chile

santiago, Chile

Mario Fernandez

Associate Professor

Urology

CLÍNICA ALEMANA DE SANTIAGO

Santiago, Chile

Luis Leon

Head of Bioinformatics and Computational Biology

Technology

PhageLab

Santiago, Chile

Susana Eyheramendy

Full Professor

Universidad Adolfo Ibánez

Santiago, Chile

Maria Repetto

Profesor Titular

Center for Genetics and Genomics

FACULTAD DE MEDICINA CLINICA ALEMANA-UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

Jaime Gutierrez

Associate Professor and Researcher

Tecnología Médica

Universidad San Sebastián

Santiago, Chile

FERNANDO TORRES

Full Professor

Instituto de Biología

PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

VALPARAISO, Chile

Rene Lopez

Clinical and research fellow

Réanimation médicale

Hôpital Saint Louis

París, Francia

Jerónimo Graf

Juan Correa

Investigador

Centro Producción del Espacio

Universidad de Las Américas

Santiago, Chile

Estefania Nova

Assistant Professor

Clinical Biochemistry & Immunology

University of Concepcion

Concepción , Chile

Felipe Reyes

Assistant professor

Universidad de S

Santiago de Chile, Chile

Monique Le Corre

Assistant Professor

Faculty of medicine, Pediatric division

Pontificia Universidad Catolica de Chile

Santiago, Chile

Gerardo Acosta

Full Professor

INSTITUTO DE MEDICINA PREVENTIVA VETERINARIA, FACULTAD DE CIENCIAS VETERINARIAS, UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

Rodrigo Pérez

coordinador de investigación

Paciente Critico

Clínica Alemana de Santiago

Vitacura, Chile

Grazielle Ribeiro

PhD candidate

Medicina

Universidad del Desarrollo- UDD

Santiago, Chile

Pablo Cañón

Académico Regular

Escuela de Agronomía

Universidad Mayor de Chile

Santiago, Chile

Nicole Tischler

Investigadora Titular

Molecular Virology Laboratory

Fundación Ciencia para la Vida

Santiago, Chile

Ramon Palma

Full Professor

Ecología

Pontificia Universidad Católica de Chile; Facultad de Ciencias Biológicas

Santiago, Chile

Ricardo Soto

PROFESOR ASOCIADO

FACULTAD DE MEDICINA

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Dusan Boric

Profesor Agregado

PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

VALPARAISO, Chile

Felipe Martinez

Associate Professor

Pontificia Universidad Católica de Chile

Santiago, Chile

Marcelo Lopez

Profesor Titular

Infectologia e Inmunologia Pediatrica

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Claudia Marco

Jefe de Unidad

Gerencia de Innovación y transformación Digital

Red de Salud UC CHRISTUS

Santiago, Chile

Maria Poli

Associate Professor

Pediatrics

Universidad del Desarrollo

Lo Barnechea, Chile

Maria Bono

Profesor titular

Biologia

UNIVERSIDAD DE CHILE

Santiago, Chile

Claudio Acuña

Profesosr Asociado

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

Yalda Lucero

Profesor Asistente

Programa de Microbiología y Micología; Departamento de Pediatría y Cirugía infantil;

DIVISIÓN NORTE, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE, DEPARTAMENTO DE PEDIATRÍA Y CIRUGÍA INFANTIL-HOSPITAL LUIS CALVO MACKENNA

Santiago, Chile

Jessica Martinez

Assistant professor

Universidad del Desarrollo

Santiago, Chile

Matias Florenzano

Medico planta

Medicina Respiratoria

Instituto Nacional del Torax

Santiago, Chile

Carmen Imarai

Profesor Titular

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

Iván Flores

Post Doc

Progama de Inmunología

Universidad de Chile

Santiago, Chile

Fernando Valiente

Profesor Asociado

ICBM

Universidad de Chile

Santiago, Chile

Carlos Barrera

Funcionario

Biología

Universidad de Santiago de Chile

Santiago, Chile

Paula Muñoz

Clinical Research Center Director

Universidad del Desarrollo

Santiago, Chile

Luis Canales

Académico

Economía y Negocios

Universidad de Talca

Talca, Chile

Alejandro Escobar

assistant professor

Institute for Research in Dental Sciences

UNIVERSIDAD DE CHILE

Santiago, Chile

ricardo fadic

Jefe de Division

Division de Neurociencias

DEPARTAMENTO DE NEUROLOGÍA, FACULTAD DE MEDICINA, P. UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Dona Benadof

Jefe laboratorio

laboratorio clinico

Hospital Roberto del río

santiago , Chile

Maria Cecilia Vial Cox

Líneas de Investigación

Educación

Cellular and Molecular Biology, Pontificia Universidad Católica de Chile. Chile, 2008

Experiencia Académica

post doctoral fellow Full Time

Profesor Asistente Full Time

Profesor Asociado Full Time

Experiencia Profesional

Post doctoral fellow Full Time

Profesor Asistente Full Time

Profesor Asociado Full Time

Formación de Capital Humano

Difusión y Transferencia

Article (42)

Proyecto (18)

Collaborative network on immunopathogenesis of Hantavirus Infection

PROMETHEUS=> A PLATFORM FOR RAPID DEVELOPMENT OF HUMAN ANTIBODY-BASED THERAPEUTICS AND PROPHYLACTICS AGAINST EMERGING VIRAL THREATS

Ecology and Evolutionary Epidemiology of Andes Hantavirus and its Associated Rodent Reservoir

Understanding host response to ANDV infection, immunological and transcriptomics approach

VIRAL QUASISPECIES, ORAL HOST IMMUNE AND CONSTITUTIVE FACTORS IN ANDES VIRUS INFECTED CASES AND EXPOSED SUBJECTS=> ROLE IN INFECTION AND TRANSMISSION.

Anomalías congénitas y trastornos del desarrollo=> Evaluación de costo-efectividad de las nuevas herramientas diagnósticas

EXPLORANDO LA SENSIBILIDAD AL ESTRES EN INFANTES=> UN ESTUDIO GENETICO, PSICOBIOLOGICO Y VINCULAR

GENETIC MODIFIERS OF THE CARDIOVASCULAR PHENOTYPE OF CHROMOSOME 22Q11 MICRODELETION SYNDROME=> NEXT-GENERATION SEQUENCING OF CANDIDATE REGIONS IDENTIFIED BY GENOME-WIDE ASSOCIATION ANALYSIS

GENETIC VARIANTS RELATED TO PRESENCE OF BLADDER UROTHELIAL CARCINOMA IN A HIGH-RISK, ARSENIC-EXPOSED POPULATION IN NORTHERN CHILE (ANTOFAGASTA)=> A GENOME-WIDE ASSOCIATION STUDY.

Host Genetic Factors and Severity of Andes hantavirus Infection=> a Genome Wide Association Study

Andes VIrus Transmission and Pathogenesis in Chile

GENETIC MODIFIERS OF THE 22Q11 MICRODELETION SYNDROME=> A GENOME-WIDE ASSOCIATION STUDY

Center of Aging and regeneration (CARE)

center for cellular regulation and pathology FONDAP

Review (2)