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Jose Manuel Munita Sepulveda

Profesor Asociado

FACULTAD DE MEDICINA CLINICA ALEMANA- UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

Mechanisms of bacterial resistance to antimicrobials Molecular epidemiology and transmission dynamics of antibiotic-resistant organisms Clinical impact of bacterial resistance

Medico Cirujano, UNIVERSIDAD DE LOS ANDES. Chile, 2004
Infectious Diseases, University of Texas Health Science Center at Houston. Estados Unidos, 2014
Internal Medicine, Facultad de Medicina Clinica Alemana - Universidad del Desarrollo. Chile, 2007
Physician, UNIVERSIDAD DE LOS ANDES. Chile

Docente Part Time

FACULTAD DE MEDICINA CLINICA ALEMANA- UNIVERSIDAD DEL DESARROLLO

2007 - 2011
Profesor Asociado Part Time

FACULTAD DE MEDICINA CLINICA ALEMANA- UNIVERSIDAD DEL DESARROLLO

2016 - A la fecha
Profesor Asistente Adjunto Part Time

THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON

2016 - A la fecha

Medico Internista Full Time

Hospital Padre Hurtado

Santiago, Chile

2007 - 2011
Staff, Unidad de Paciente Critico Part Time

Clinica Alemana de Santiago

Santiago, Chile

2008 - 2011

ASM Infectious Disease Fellow Travel Grant

American Society for Microbiology

Estados Unidos, 2012

Travel grant awarded to fellows with presenting outstanding work in the annual ASM meeting
ASM ICAAC Infectious Diseases Fellows Grant Program

American Society for Microbiology

Chile, 2013

Travel grant awarded to outstanding fellows who were invited for a Fellows Program to be held during the annual ICAAC meeting
IDWeek Trainee Travel Grant

Infectious Diseases Society of America

Chile, 2013

Travel Grant awarded by the Infectious Diseases Society of America to outstanding fellows to present their work at the annual IDSA meeting
Scholarship for Clinical and Research Training

Clinica Alemana de Santiago

Chile, 2011

Beca para formación de especialistas en el extranjero otorgada a medico de Clínica Alemana por medio de un concurso competitivo. En este caso la beca otorgada fue por los años 2011 al 2014
Scholarship for Medical Subspecialties Abroad

CONICYT

Chile, 2014

Becas de sub especialidades medicas para formación en el extranjero
Fellow

American College of Physicians

Estados Unidos, 2017

Nombramiento oficial como Fellow del American College of Physicians


Molecular Mechanisms of Resistance to Ceftazidime/Avibactam in Clinical Isolates of Enterobacterales and Pseudomonas aeruginosa in Latin American Hospitals Mojica, Maria Fernanda; De La Cadena, Elsa; Garcia-Betancur, Juan Carlos; Porras, Jessica; Novoa-Caicedo, Isabella; Paez-Zamora, Laura; Pallares, Christian; Appel, Tobias Manuel; Radice, Marcela A. A.; Castaneda-Mendez, Paulo; Gales, Ana C. C.; Munita, Jose M.; Villegas, Maria Virginia Article ISI MSPHERE (2023)
Multiomics characterization of methicillin-resistant Staphylococcus aureus (MRSA) isolates with heterogeneous intermediate resistance to vancomycin (hVISA) in Latin America Castro, Betsy E.; Rios, Rafael; Carvajal, Lina P.; Vargas, Monica L.; Cala, Monica P.; Leon, Lizeth; Hanson, Blake; Dinh, An Q.; Ortega-Recalde, Oscar; Seas, Carlos; Munita, Jose M.; Arias, Cesar A.; Rincon, Sandra; Reyes, Jinnethe; Diaz, Lorena Article ISI JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2023)
Multisite Detection of Tn1549-Mediated vanB Vancomycin Resistance in Multidrug-Resistant Enterococcus faecalis ST6 in Texas and Florida Simar, Shelby R.; Tran, Truc T.; Rydell, Kirsten B.; Panesso, Diana; Contreras, German A.; Munita, Jose M.; Cifuentes, Renzo O.; Abbo, Lilian M.; Sahasrabhojane, Pranoti; Dinh, An Q.; Axell-House, Dierdre B.; Savidge, Tor; Shelburne, Samuel A.; Hanson, Blake M.; Arias, Cesar A. Article ISI ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2023)
A dual treatment blocks alcohol binge-drinking relapse: Microbiota as a new player Ezquer, Fernando; Quintanilla, Maria Elena; Morales, Paola; Santapau, Daniela; Munita, Jose Manuel; Moya-Flores, Francisco; Ezquer, Marcelo; Herrera-Marschitz, Mario; Israel, Yedy Article ISI DRUG AND ALCOHOL DEPENDENCE (2022)
Acquisition of resistance to ceftazidime-avibactam during infection treatment in Pseudomonas aeruginosa through D179Y mutation in one of two bla(KPC-2) gene copies without losing carbapenem resistance Garcia, Patricia; Brito, Barbara; Alcalde-Rico, Manuel; Munita, Jose M.; Martinez, Jose R. W.; Olivares-Pacheco, Jorge; Quiroz, Valeria; Wozniak, Aniela Article ISI FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2022)
Antimicrobial Susceptibility Testing for Enterococci Khan, Ayesha; Miller, William R.; Axell-House, Dierdre; Munita, Jose M.; Arias, Cesar A. Article ISI JOURNAL OF CLINICAL MICROBIOLOGY (2022)
Clinical characteristics, microbiology and outcomes of a cohort of patients treated with ceftolozane/tazobactam in acute care inpatient facilities, Houston, Texas, USA Tran, Truc T.; Cabrera, Nicolo L.; Gonzales-Luna, Anne J.; Carlson, Travis J.; Alnezary, Faris; Miller, William R.; Sakurai, Aki; Dinh, An Q.; Rydell, Kirsten; Rios, Rafael; Diaz, Lorena; Hanson, Blake M.; Munita, Jose M.; Pedroza, Claudia; Shelburne, Samuel A.; Aitken, Samuel L.; Garey, Kevin W.; Dillon, Ryan; Puzniak, Laura; Arias, Cesar A. Article ISI JAC-ANTIMICROBIAL RESISTANCE (2022)
Comparative In Vitro Activity of Ceftolozane/Tazobactam against Clinical Isolates of Pseudomonas aeruginosa and Enterobacterales from Five Latin American Countries Garcia-Betancur, Juan Carlos; De la Cadena, Elsa; Mojica, Maria F.; Hernandez-Gomez, Cristhian; Correa, Adriana; Radice, Marcela A.; Castaneda-Mendez, Paulo; Jaime-Villalon, Diego A.; Gales, Ana C.; Munita, Jose M.; Villegas, Maria Virginia Article ISI ANTIBIOTICS-BASEL (2022)
Contemporary Clinical and Molecular Epidemiology of Vancomycin-Resistant Enterococcal Bacteremia: A Prospective Multicenter Cohort Study (VENOUS I) Contreras, German A.; Munita, Jose M.; Simar, Shelby; Luterbach, Courtney; Dinh, An Q.; Rydell, Kirsten; Sahasrabhojane, Pranoti, V; Rios, Rafael; Diaz, Lorena; Reyes, Katherine; Zervos, Marcus; Misikir, Helina M.; Sanchez-Petitto, Gabriela; Liu, Catherine; Doi, Yohei; Abbo, Lilian M.; Shimose, Luis; Seifert, Harald; Gudiol, Carlota; Barberis, Fernanda; Pedroza, Claudia; Aitken, Samuel L.; Shelburne, Samuel A.; Duin, Davidvan; Tran, Truc T.; Hanson, Blake M.; Arias, Cesar A. Article ISI OPEN FORUM INFECTIOUS DISEASES (2022)
First wave of SARS-CoV-2 in Santiago Chile: Seroprevalence, asymptomatic infection and infection fatality rate Vial, Pablo A.; Gonzalez, Claudia; Apablaza, Mauricio; Vial, Cecilia; Lavin, M. Estela; Araos, Rafael; Rubilar, Paola; Icaza, Gloria; Florea, Andrei; Perez, Claudia; Concha, Paula; Bastias, Diego; Errazuriz, Maria Paz; Perez, Ruth; Guzman, Francisco; Olea, Andrea; Guzman, Eugenio; Correa, Juan; Munita, Jose Manuel; Aguilera, Ximena Article ISI EPIDEMICS (2022)
Molecular epidemiology of carbapenem-resistant Klebsiella pneumoniae in China, 2016-20 Liu, Congcong; Dong, Ning; Chan, Edward Wai Chi; Chen, Sheng; Zhang, Rong Article ISI LANCET INFECTIOUS DISEASES (2022)
Molecular mechanisms leading to ceftolozane/tazobactam resistance in clinical isolates of Pseudomonas aeruginosa from five Latin American countries Mojica, Maria F.; De la Cadena, Elsa; Rios, Rafael; Carlos Garcia-Betancur, Juan; Diaz, Lorena; Reyes, Jinnethe; Hernandez-Gomez, Cristhian; Radice, Marcela; Gales, Ana C.; Castaneda Mendez, Paulo; Munita, Jose M.; Jose Pallares, Christian; Martinez, Jose R. W.; Virginia Villegas, Maria Article ISI FRONTIERS IN MICROBIOLOGY (2022)
New Perspectives on Antimicrobial Agents: Long-Acting Lipoglycopeptides Tran, Truc T.; Villegas, Sara Gomez; Aitken, Samuel L.; Butler-Wu, Susan M.; Soriano, Alex; Werth, Brian J.; Munita, Jose M. Article ISI ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2022)
Phenotypic and Genotypic Characterization of Macrolide, Lincosamide and Streptogramin B Resistance among Clinical Methicillin-Resistant Staphylococcus aureus Isolates in Chile Quezada-Aguiluz, Mario; Aguayo-Reyes, Alejandro; Carrasco, Cinthia; Mejias, Daniela; Saavedra, Pamela; Mella-Montecinos, Sergio; Opazo-Capurro, Andres; Bello-Toledo, Helia; Munita, Jose M.; Hormazabal, Juan C.; Gonzalez-Rocha, Gerardo Article ISI ANTIBIOTICS-BASEL (2022)
Real-World Performance of Susceptibility Testing for Ceftolozane/Tazobactam against Non-Carbapenemase-Producing Carbapenem-Resistant Pseudomonas aeruginosa Rivas, Lina; Alcalde-Rico, Manuel; Martinez, Jose R. W.; Victoria Moreno, Maria; Rojas, Pamela; Wozniak, Aniela; Garcia, Patricia; Olivares-Pacheco, Jorge; Miller, William R.; Arias, Cesar A.; Khan, Ayesha; Munita, Jose M. Article ISI ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2022)
Role of the multi-drug efflux systems on the baseline susceptibility to ceftazidime/avibactam and ceftolozane/tazobactam in clinical isolates of non-carbapenemase-producing carbapenem-resistant Pseudomonas aeruginosa Jose Contreras-Gomez, Maria; Martinez, Jose R. W.; Rivas, Lina; Riquelme-Neira, Roberto; Ugalde, Juan A.; Wozniak, Aniela; Garcia, Patricia; Munita, Jose M.; Olivares-Pacheco, Jorge; Alcalde-Rico, Manuel Article ISI FRONTIERS IN PHARMACOLOGY (2022)
Transmission of gram-negative antibiotic-resistant bacteria following differing exposure to antibiotic-resistance reservoirs in a rural community: a modelling study for bloodstream infections Allel, Kasim; Gosce, Lara; Araos, Rafael; Toro, Daniel; Ferreccio, Catterina; Munita, Jose M.; Undurraga, Eduardo A.; Panovska-Griffiths, Jasmina Article ISI SCIENTIFIC REPORTS (2022)
Antimicrobial resistance in wildlife and in the built environment in a wildlife rehabilitation center Baros Jorquera, Carla; Moreno-Switt, Andrea, I; Sallaberry-Pincheira, Nicole; Munita, Jose M.; Flores Navarro, Camila; Tardone, Rodolfo; Gonzalez-Rocha, Gerardo; Singer, Randall S.; Bueno, Irene Article ISI ONE HEALTH (2021)
ESBL-Producing Escherichia coli Carrying CTX-M Genes Circulating among Livestock, Dogs, and Wild Mammals in Small-Scale Farms of Central Chile Benavides, Julio A.; Salgado-Caxito, Marilia; Opazo-Capurro, Andres; Gonzalez Munoz, Paulina; Pineiro, Ana; Otto Medina, Macarena; Rivas, Lina; Munita, Jose; Millan, Javier Article ISI ANTIBIOTICS-BASEL (2021)
Evaluation of two fluorescence immunoassays for the rapid detection of SARS-CoV-2 antigen-new tool to detect infective COVID-19 patients Porte, Lorena; Legarraga, Paulette; Iruretagoyena, Mirentxu; Vollrath, Valeska; Pizarro, Gabriel; Munita, Jose; Araos, Rafael; Weitzel, Thomas Article ISI PEERJ (2021)
Isolation of Ciprofloxacin and Ceftazidime-Resistant Enterobacterales From Vegetables and River Water Is Strongly Associated With the Season and the Sample Type Diaz-Gavidia, Constanza; Barria, Carla; Rivas, Lina; Garcia, Patricia; Alvarez, Francisca P.; Gonzalez-Rocha, Gerardo; Opazo-Capurro, Andres; Araos, Rafael; Munita, Jose M.; Cortes, Sandra; Olivares-Pacheco, Jorge; Adell, Aiko D.; Moreno-Switt, Andrea I. Article ISI FRONTIERS IN MICROBIOLOGY (2021)
Longitudinal assessment of SARS-CoV-2 IgG seroconversionamong front-line healthcare workers during the first wave of the Covid-19 pandemic at a tertiary-care hospital in Chile Iruretagoyena, Mirentxu; Vial, Macarena R.; Spencer-Sandino, Maria; Gaete, Pablo; Peters, Anne; Delgado, Iris; Perez, Inia; Calderon, Claudia; Porte, Lorena; Legarraga, Paulette; Anderson, Alicia; Aguilera, Ximena; Vial, Pablo; Weitzel, Thomas; Munita, Jose M. Article ISI BMC INFECTIOUS DISEASES (2021)
Multi-country cross-sectional study of colonization with multidrug-resistant organisms: protocol and methods for the Antibiotic Resistance in Communities and Hospitals (ARCH) studies Sharma, Aditya; Luvsansharav, Ulzii-Orishikh; Paul, Prabasaj; Lutgring, Joseph D.; Call, Douglas R.; Omulo, Sylvia; Laserson, Kayla; Araos, Rafael; Munita, Jose M.; Verani, Jennifer; Chowdhury, Fahmida; Muneer, Syeda Mah-E; Espinosa-Bode, Andres; Ramay, Brooke; Cordon-Rosales, Celia; Kumar, C. P. Girish; Bhatnagar, Tarun; Gupta, Neil; Park, Benjamin; Smith, Rachel M. Article ISI BMC PUBLIC HEALTH (2021)
Selective digestive decontamination with oral colistin plus gentamicin for persistent bacteraemia caused by non-carbapenemase-producing carbapenem-resistant Klebsiella pneumoniae in a neutropenic patient Spencer-Sandino, Maria; Riquelme-Neira, Roberto; Shropshire, William C.; Dinh, An Q.; Gonzalez-Rocha, Gerardo; Gonzalez-Munoz, Paulina; Vera-Leiva, Alejandra; Araos, Rafael; Hanson, Blake; Arias, Cesar A.; Munita, Jose M. Article ISI (2021)
Clinical Predictive Model of Multidrug Resistance in Neutropenic Cancer Patients with Bloodstream Infection Due to Pseudomonas aeruginosa Gudiol C.; Albasanz-Puig A.; Laporte-AmargÃ³s J.; PallarÃ¨s N.; Mussetti A.; Ruiz-Camps I.; Puerta-Alcalde P.; Abdala E.; Oltolini C.; Akova M.; Montejo M.; Mikulska M.; MartÃn-DÃ¡vila P.; Herrera F.; Gasch O.; Drgona L.; Paz Morales H.; Brunel A.-S.; GarcÃa E.; Isler B.; Kern W.V.; Morales I.; Maestro-De La Calle G.; Montero M.; Kanj S.S.; Sipahi O.R.; Calik S.; MÃ¡rquez-GÃ³mez I.; Marin J.I.; Gomes M.Z.R.; Hemmatti P.; Araos R.; Peghin M.; Del Pozo J.L.; YÃ¡Ã±ez L.; Tilley R.; Manzur A.; Novo A.; CarratalÃ J.; Cuervo G.; Escrihuela-Vidal F.; Tubau F.; TebÃ© C.; Arias M.R.; Aguilar-Company J.; Larrosa N.; Cardozo C.; Garcia-Vidal C.; Karim-Yaqub I.; Greco R.; Cichero P.; Ayaz C.M.; CÃ©spedes R.; LÃ³pez-Soria L.; Magnasco L.; FortÃºn J.; Torres D.; BotÃ© A.; Espasa M.; Montaguti M.H.; Bochud P.-Y.; Manuel O.; Carrasco S.T.; LÃ³pez J.S.; Bertz H.; Rieg S.; De Cueto M.; RodrÃguez-BaÃ±o J.; Lizasoain M.; Aguado J.M.; Horcajada J.P.; El Zein S.; Jabbour J.-F.; Uyan-Onal A.; Nazli-Zeka A.; Palop, B.; Correa L.C.; Aparecida Da Silva Machado A.; TonhÃ¡ J.P.S.; Maschmeyer G.; Munita J.; Bassetti M.; Castaldo N.; Sangro Del AlcÃ¡zar P. Article ISI SCOPUS ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2020)
Detection of heterogeneous vancomycin intermediate resistance in MRSA isolates from Latin America Castro, Betsy E.; Berrio, Maritza; Vargas, Monica L.; Carvajal, Lina P.; Millan, Lina, V; Rios, Rafael; Hernandez, Angie K.; Rincon, Sandra; Cubides, Paola; Forero, Erika; Dinh, An; Seas, Carlos; Munita, Jose M.; Arias, Cesar A.; Reyes, Jinnethe; Diaz, Lorena Article ISI JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2020)
Genomic Epidemiology of Vancomycin-Resistant Enterococcus faecium (VREfm) in Latin America: Revisiting The Global VRE Population Structure Rios R.; Reyes J.; Carvajal L.P.; Rincon S.; Panesso D.; Echeverri A.M.; Dinh A.; Kolokotronis S.-O.; Narechania A.; Tran T.T.; Munita J.M.; Murray B.E.; Planet P.J.; Arias C.A.; Diaz L. Article ISI SCOPUS SCIENTIFIC REPORTS (2020)
In Vitro Susceptibility to Ceftazidime/Avibactam and Comparators in Clinical Isolates of Enterobacterales from Five Latin American Countries Appel T.M.; Mojica M.F.; De La Cadena E.; Pallares C.J.; Radice M.A.; CastaÃ±eda-MÃ©ndez P.; Jaime-VillalÃ³n D.A.; Gales A.C.; Munita J.M.; Villegas M.V. Article ISI SCOPUS ANTIBIOTICS-BASEL (2020)
A Multicenter Study To Evaluate Ceftaroline Breakpoints: Performance in an Area with High Prevalence of Methicillin-Resistant Staphylococcus aureus Sequence Type 5 Lineage Khan, Ayesha; Rivas, Lina M.; Spencer, Maria; Martinez, Rodrigo; Lam, Marusella; Rojas, Pamela.; Porte, Lorena; Silva, Francisco; Braun, Stephanie; Valdivieso, Francisca; Mvlhauser, Margareta; Lafourcade, Monica; Miller, William R.; Garcia, Patricia; Arias, Cesar A.; Munita, Jose M Article ISI SCOPUS JOURNAL OF CLINICAL MICROBIOLOGY (2019)
A One Health - One World initiative to control antibiotic resistance: A Chile - Sweden collaboration Cabrera-Pardo, Jaime R.; Lood, Rolf; Udekwu, Klas; Gonzalez-Rocha, Gerardo; Munita, Jose M; Järhult, Josef D.; Opazo-Capurro, Andrés Article ISI SCOPUS ONE HEALTH (2019)
Higher MICs (> 2 mg/L) Predict 30-Day Mortality in Patients With Lower Respiratory Tract Infections Caused by Multidrug- and Extensively Drug-Resistant Pseudomonas aeruginosa Treated With Ceftolozane/Tazobactam Rodriguez-Nunez, O; Perianez-Parraga, L; Oliver, A; Munita JM; Bote, A; Gasch, O; Nuvials, X; Dinh, A; Shaw, R.; Lomas, JM; Torres, V; Caston, J; Araos, R; Abbo, LM; Rakita, R; Perez, F; Aitken, SL; Arias, CA; Martin-Pena, ML; Colomar, A; Nunez, MB; Mensa, J; Martinez, JA; Soriano, A Article ISI OPEN FORUM INFECTIOUS DISEASES (2019)
A Natural Deep Eutectic Solvent Formulated to Stabilize beta-Lactam Antibiotics Olivares, B; Martinez, F; Rivas, L; Calderon, C; Munita JM; Campodonico, PR Article ISI SCOPUS SCIENTIFIC REPORTS (2018)
In Vivo Resistance to Ceftolozane/Tazobactam in Pseudomonas aeruginosa Arising by AmpC- and Non-AmpC-Mediated Pathways Skoglund, E; Abodakpi, H; Rios, R; Diaz, L; De la Cadena, E; Dinh, AQ; Ardila, J; Miller, WR; Munita JM; Arias, CA; Tam, VH; Tran, TT Article WOS-ESCI CASE REPORTS IN INFECTIOUS DISEASES (2018)
Influence of inoculum effect on the efficacy of daptomycin monotherapy and in combination with -lactams against daptomycin-susceptible enterococcus faecium harboring liasr substitutions Kebriaei R.; Rice S.A.; Singh K.V.; Stamper K.C.; Dinh A.Q.; Rios R.; Diaz L.; Murray, B.E.; Munita, J.M.; Tran, T.T.; Arias, C.A.; Rybak M.J. Article SCOPUS Antimicrobial Agents and Chemotherapy (2018)
Influence of Inoculum Effect on the Efficacy of Daptomycin Monotherapy and in Combination with beta-Lactams against Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions Kebriaei, R; Rice, SA; Singh, KV; Stamper, KC; Dinh, AQ; Rios, R; Diaz L.; Murray, BE; Munita JM; Tran, TT; Arias, CA; Rybak, MJ Article ISI ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2018)
The Cefazolin Inoculum Effect Is Associated With Increased Mortality in Methicillin-Susceptible Staphylococcus aureus Bacteremia Miller, WR; Seas, C; Carvajal, LP; Diaz L.; Echeverri, AM; Ferro, C.; Rios, R; Porras, P; Luna, C; Gotuzzo, E; Munita JM; Nannini, E; Carcamo, C; Reyes, J; Arias, CA Article ISI OPEN FORUM INFECTIOUS DISEASES (2018)
A Prospective Cohort Multicenter Study of Molecular Epidemiology and Phylogenomics of Staphylococcus aureus Bacteremia in Nine Latin American Countries. Arias, Cesar A; Reyes, Jinnethe; Carvajal, Lina Paola; Rincon, Sandra; Diaz, Lorena; Panesso, Diana; Ibarra, Gabriel; Rios, Rafael; Munita, Jose M; Salles, Mauro J; Alvarez-Moreno, Carlos; Labarca, Jaime; Garcia, Coralith; Luna, Carlos M; Mejia-Villatoro, Carlos; Zurita, Jeannete; Guzman-Blanco, Manuel; Rodriguez-Noriega, Eduardo; Narechania, Apurva; Rojas, Laura J; Planet, Paul J; Weinstock, George M; Gotuzzo, Eduardo; Seas, Carlos Article Antimicrobial agents and chemotherapy (2017)
Ceftaroline-Resistant, DaptomycinTolerant, and Heterogeneous Vancomycin-Intermediate MethicillinResistant Staphylococcus aureus Causing Infective Endocarditis Nigo, Masayuki; Diaz, Lorena; Carvajal, Lina P.; Tran, Truc T.; Rios, Rafael; Panesso, Diana; Garavito, Juan D.; Miller, William R.; Wanger, Audrey; Weinstock, George; Munita, Jose M.; Arias, Cesar A.; Chambers, Henry F. Article ISI SCOPUS ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)
Daptomycin non-susceptible Enterococcus faecium in leukemia patients: Role of prior daptomycin exposure DiPippo, Adam J.; Tverdek, Frank P.; Tarrand, Jeffrey J.; Munita, Jose M.; Tran, Truc T.; Arias, Cesar A.; Shelburne, Samuel A.; Aitken, Samuel L. Article ISI SCOPUS JOURNAL OF INFECTION (2017)
Gram-Positive Bacterial Infections: Research Priorities, Accomplishments, and Future Directions of the Antibacterial Resistance Leadership Group Doernberg, Sarah B.; Lodise, Thomas P.; Thaden, Joshua T.; Munita, Jose M.; Cosgrove, Sara E.; Arias, Cesar A.; Boucher, Helen W.; Corey, G. Ralph; Lowy, Franklin D.; Murray, Barbara; Miller, Loren G.; Holland, Thomas L. Article ISI SCOPUS Clinical Infectious Diseases (2017)
Multicenter Evaluation of Ceftolozane/Tazobactam for Serious Infections Caused by Carbapenem-Resistant Pseudomonas aeruginosa Munita, Jose M.; Aitken, Samuel L.; Miller, William R.; Perez, Federico; Rosa, Rossana; Shimose, Luis A.; Lichtenberger, Paola N.; Abbo, Lilian M.; Jain, Rupali; Nigo, Masayuki; Wanger, Audrey; Araos, Rafael; Tran, Truc T.; Adachi, Javier; Rakita, Robert; Shelburne, Samuel; Bonomo, Robert A.; Arias, Cesar A. Article ISI SCOPUS CLINICAL INFECTIOUS DISEASES (2017)
Whole-Genome Sequencing Accurately Identifies Resistance to Extended-Spectrum beta-Lactams for Major Gram-Negative Bacterial Pathogens Shelburne, Samuel A.; Kim, Jiwoong; Munita, Jose M.; Sahasrabhojane, Pranoti; Shields, Ryan K.; Press, Ellen G.; Li, Xiqi; Arias, Cesar A.; Cantarel, Brandi; Jiang, Ying; Kim, Min S.; Aitken, Samuel L.; Greenberg, David E. Article ISI SCOPUS Clinical Infectious Diseases (2017)
Fungal empyema thoracis in cancer patients Nigo, Masayuki; Vial, Macarena R.; Munita, Jose M; Jiang, Ying; Tarrand, Jeffrey; Jimenez, Carlos A.; Kontoyiannis, Dimitrios P. Article ISI SCOPUS Journal of Infection (2016)
Influence of Minimum Inhibitory Concentration in Clinical Outcomes of Enterococcus faecium Bacteremia Treated with Daptomycin: Is it Time to Change the Breakpoint? Shukla B.S.; Shelburne, S.; Reyes, K.; Kamboj M.; Lewis J.D.; Rincon S.L.; Reyes, J; Carvajal, L.P.; Panesso, D; Sifri C.D.; Zervos M.J.; Pamer E.G.; Tran, T.T.; Adachi J.; Munita, J.M.; Hasbún R.; Arias, C.A. Article ISI SCOPUS Clinical Infectious Diseases (2016)
Mechanisms of Antibiotic Resistance. Munita, Jose M; Arias, Cesar A Article Microbiology spectrum (2016)
A liaR Deletion Restores Susceptibility to Daptomycin and Antimicrobial Peptides in Multidrug-Resistant Enterococcus faecalis Reyes, J; Panesso, D; Tran, TT; Mishra, NN; Cruz, MR; Munita JM; Singh, KV; Yeaman, MR; Murray, BE; Shamoo Y.; Garsin D; Bayer, AS; Arias, CA Article ISI SCOPUS Journal of Infectious Diseases (2015)
Deletion of liaR Reverses Daptomycin Resistance in Enterococcus faecium Independent of the Genetic Background Panesso, D; Reyes, J; Gaston, EP; Deal M.; Londono, A; Nigo, M; Munita JM; Miller, WR; Shamoo Y.; Tran, TT; Arias, CA Article ISI SCOPUS Antimicrobial Agents and Chemotherapy (2015)
Evolving Resistance Among Gram-positive Pathogens Munita JM; Bayer, AS; Arias, CA Article ISI SCOPUS Clinical Infectious Diseases (2015)
Mechanisms of drug resistance: daptomycin resistance Tran, TT; Munita JM; Arias, CA Article ISI SCOPUS Annals of the New York Academy of Sciences (2015)
Methicillin-Susceptible, Vancomycin-Resistant Staphylococcus aureus, Brazil Panesso, D; Planet, PJ; Diaz L.; Hugonnet, JE; Tran, TT; Narechania, A.; Munita JM; Rincon, S.; Carvajal, LP; Reyes, J; Londono, A; Smith, H; Sebra, R; Deikus, G.; Weinstock, GM; Murray, BE; Rossi F.; Arthur, M; Arias, CA Article ISI SCOPUS Emerging Infectious Diseases (2015)
Transferable Vancomycin Resistance in a Community-Associated MRSA Lineage Rossi F.; Diaz L.; Wollam, A; Panesso, D; Zhou, YJ; Rincon, S.; Narechania, A.; Xing, GL; Di Gioia, TSR; Doi A.; Tran, TT; Reyes, J; Munita JM; Carvajal, LP; Hernandez-Roldan, A; Brandao, D; van der Heijden, IM; Murray, BE; Planet, PJ; Weinstock, GM; Arias, CA Article ISI SCOPUS NEW ENGLAND JOURNAL OF MEDICINE (2014)
What's New in the Treatment of Enterococcal Endocarditis? Nigo, M; Munita JM; Arias, CA; Murray, BE Article ISI SCOPUS CURRENT INFECTIOUS DISEASE REPORTS (2014)
Whole-Genome Analyses of Enterococcus faecium Isolates with Diverse Daptomycin MICs Diaz L.; Tran, TT; Munita JM; Miller, WR; Rincon, S.; Carvajal, LP; Wollam, A; Reyes, J; Panesso, D; Rojas, NL; Shamoo Y.; Murray, BE; Weinstock, GM; Arias, CA Article ISI SCOPUS ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)
A liaF Codon Deletion Abolishes Daptomycin Bactericidal Activity against Vancomycin-Resistant Enterococcus faecalis Munita JM; Tran, TT; Diaz L.; Panesso, D; Reyes, J; Murray, BE; Arias, CA Article ISI SCOPUS Antimicrobial Agents and Chemotherapy (2013)
Daptomycin-Resistant Enterococcus faecalis Diverts the Antibiotic Molecule from the Division Septum and Remodels Cell Membrane Phospholipids Tran, TT; Panesso, D; Mishra, NN; Mileykovskaya, E; Guan, ZQ; Munita JM; Reyes, J; Diaz L.; Weinstock, GM; Murray, BE; Shamoo Y.; Dowhan, W; Bayer, AS; Arias, CA Article ISI SCOPUS mBio (2013)
Dissecting the Mechanisms of Linezolid Resistance in a Drosophila melanogaster Infection Model of Staphylococcus aureus Diaz L.; Kontoyiannis, DP; Panesso, D; Albert, ND; Singh, KV; Tran, TT; Munita JM; Murray, BE; Arias, CA Article ISI SCOPUS Journal of Infectious Diseases (2013)
Whole-Genome Analysis of a Daptomycin-Susceptible Enterococcus faecium Strain and Its Daptomycin-Resistant Variant Arising during Therapy Tran, TT; Panesso, D; Gao, HY; Roh JH; Munita JM; Reyes, J; Diaz L.; Lobos, EA; Shamoo Y.; Mishra, NN; Bayer, AS; Murray, BE; Weinstock, GM; Arias, CA Article ISI SCOPUS Antimicrobial Agents and Chemotherapy (2013)
Correlation between Mutations in liaFSR of Enterococcus faecium and MIC of Daptomycin: Revisiting Daptomycin Breakpoints Munita, J.M.; Panesso, D; Diaz L.; Tran, T.T.; Reyes, J; Wanger A.; Murray, B.E.; Arias, C.A. Article ISI SCOPUS Antimicrobial Agents and Chemotherapy (2012)
Enterococcal Endocarditis: Can We Win the War? Munita, J.M.; Arias, C.A.; Murray, B.E. Article ISI SCOPUS Current Infectious Disease Reports (2012)
Bacteremia in patients with liver cirrhosis Munita JM; Araos R.; Perez J.; Alvarez A.; Canals M.; Contreras, J.; Marcotti, A; Thompson, L; Noriega, LM Article ISI REVISTA CHILENA DE INFECTOLOGIA (2011)
Cat scratch disease associated neuroretinitis: Clinical report and review of the literature Perez J.; Munita JM; Araos R.; Lopez, JP; Stevenson, R; Gonzalez P.; Pérez D.; Noriega, LM Article ISI REVISTA CHILENA DE INFECTOLOGIA (2010)
Pandemic influenza A (H1N1) 2009 with neurological manifestations, a case series Noriega, LM; Verdugo, RJ; Araos R.; Munita JM; Díaz V.; Marcotti, A; Perez J.; Gonzalez P.; Thompson, L; Canals M.; Hoppe, A; Mounts, AW; Vial, PA Article ISI SCOPUS Influenza and other Respiratory Viruses (2010)
Cirugía pulmonar en tuberculosis Rodríguez, Macarena; Munita, José Manuel; Perez, Daniel; Bannura, Felipe; Rodríguez, Juan Carlos; Rodríguez, Patricio Article SCIELO REVISTA MEDICA DE CHILE (2009)
Surgery for pulmonary tuberculosis. Review of 33 operated patients Rodríguez, M.; Munita JM; Pérez D.; Bannura, F; Rodriguez, JC; Rodríguez, P. Article ISI REVISTA MEDICA DE CHILE (2009)
Community acquired infections with methicillin resistant strains of Staphylococcus aureus. Report of five cases Noriega, LM; Gonzalez P.; Hormazabal, JC.; Pinto, C.; Canals M.; Munita JM; Thompson, L; Marcotti, A; Perez J.; Ibanez, D; Araya, P; Canals C.; Vial, P. Article ISI REVISTA MEDICA DE CHILE (2008)


DO INTERNATIONAL MIGRANTS FACE HIGHER BACTERIAL DRUG RESISTANCE COMPARED TO NATIVES? A SYSTEMATIC REVIEW Cabieses, B; Peters, A; Acuna, MP; Uphoff, N; Astorga, S; Munita JM Abstract ISI VALUE IN HEALTH (2019)


Mechanisms of Antibiotic Resistance Munita, Jose M.; Arias, Cesar A.; Indira T. Kudva, Nancy A. Cornick, Paul J. Plummer, Qijing Zhang, Tracy L. Nicholson, John P. Bannantine, Bryan H. Bellaire BookSection (2016)
Antimicrobial Resistance: Selection vs. Induction Araos, R; Munita, Jose M.; Arias, Cesar A.; Cunha, Cheston; Morril, HJ; Rice, LB; Mylonakis, E; La Plante, KL BookSection (2015)
Skin and soft tissue infections Munita, Jose M.; Arias, Cesar A.; Vesga, O., Velez, LA., Leiderman, E., Restrepo, A BookSection (2015)
Vancomycin-resistant enterococcal infections in the ICU Munita, Jose M.; Arias, Cesar A.; Balasini, Carina; Rosa, Reina; Llerena, MC BookSection (2015)


Staphylococcus aureus comunitario resistente a cloxacilina: Comunicación de los primeros cinco casos descritos en Chile Noriega, Luis Miguel; Gonzalez, Patricia; Hormazábal, Juan Carlos; Pinto, Consuelo; Canals, Magdalena; Munita, José Manuel; Thompson, Luis; Marcotti, Alejandra; Perez, Jorge; Ibáñez, Daniel; Araya, Pamela; Canals, Claudio; Vial, Pablo CaseReport SCIELO REVISTA MEDICA DE CHILE (2008)


Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions Munita JM; Mishra, NN; alvarez, D; Tran, TT; Diaz L.; Panesso, D; Reyes, J; Murray, BE; Adachi, JA; Bayer, AS; Arias, CA EditorialMaterial ISI SCOPUS CLINICAL INFECTIOUS DISEASES (2014)
Enterococcus faecalis Infective Endocarditis: Is It Time to Abandon Aminoglycosides? Munita JM; Arias, CA; Murray, BE EditorialMaterial ISI SCOPUS Clinical Infectious Diseases (2013)


A Prospective Cohort Multicenter Study of Molecular Epidemiology and Phylogenomics of Staphylococcus aureus Bacteremia in Nine Latin American Countries (vol 61, e00816-17, 2017) Arias, CA; Reyes, J; Carvajal, LP; Rincon, S.; Diaz L.; Panesso, D; Ibarra, G; Rios, R; Munita JM; Salles, MJ; Alvarez-Moreno, C; Labarca, J; Garcia, C; Luna, CM; Mejia-Villatoro, C; Zurita, J; Guzman-Blanco, M; Rodriguez-Noriega, E; Narechania, A.; Rojas, LJ; Planet, PJ; Weinstock, GM; Gotuzzo, E; Seas, C Errata ISI SCOPUS ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2018)


Millennium Initiative for Collaborative Research On Bacterial Resistance (MICROB-R) Jose M Munita; Andrea I Moreno Switt Proyecto (2018)
Collaborative Effort to Study Multidrug-Resistant Gram-Negatives in Chile PCI (170193) Proyecto 2017-2019 Inv. Principal
Phylogenomic Analysis of the Chilean-Cordobes MRSA Clone and the Role of Heavy Metal Resistance in its Ability to Prevail in Chile FONDECYT (1171805) Proyecto 2017-2021 Inv. Principal
Genomic Characteristics of VRE Bloodstream Infections in Patients with Hematological Malignancies in Six Geographical Locations MD Anderson Cancer Center (Sister Institution Network Fund) Proyecto 2016-2018 Coinvestigador(a)
Prospective Evaluation of Clinical Outcomes of Cancer Patients with Vancomycin-Resistant E. faecium Bacteremia NIH/NIAID (NIH/NIAID) Proyecto 2016-2018 Inv. Responsable
Prospective Evaluation of Clinical Outcomes of Cancer Patients with Vancomycin-Resistant Enterococcal Bacteremia Munita, Jose M.; Cesar A. Arias Proyecto (0)


Daptomycin for the treatment of bacteraemia due to vancomycin-resistant enterococci Munita JM; Murray, BE; Arias, CA Review ISI SCOPUS INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2014)
Mechanisms of antibiotic resistance in enterococci Miller, WR; Munita JM; Arias, CA Review ISI SCOPUS EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2014)
Resistance to last resort antibiotics in Gram-positive cocci: The post-vancomycin era Rincon, S.; Panesso, D; Diaz L.; Carvajal, LP; Reyes, J; Munita JM; Arias, CA Review ISI SCOPUS BIOMEDICA (2014)

Jose Munita

Profesor Asociado

Internal Medicine

FACULTAD DE MEDICINA CLINICA ALEMANA- UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

Sandra Diaz

Associate Professor

Instituto de Ciencias e Innovación en Medicina

Universidad del Desarrollo

Santiago, Chile

Patricia García

Jefe de Laboratorio de Microbiologia

Escuela de Medicina

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE, LABORATORIO DE MICROBIOLOGÍA

Santiago, Chile

Gerardo Gonzalez

Full Professor

Microbiology

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

Andres Opazo

Profesor Asistente

Microbiología

Universidad de Concepción

Concepción, Chile

Pablo Vial

Professor

School of Medicine

ICIM/UNIVERSIDAD DEL DESARROLLO - CLÍNICA ALEMANA

Santiago, Chile

Rafael Araos

Principal Investigator

Universidad del De

Santiago, Chile

Aniela Wozniak

Coordinador de Investigación

Dept Laboratorios Clínicos

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Andrea Moreno

Profesor Asociado

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

Thomas Weitzel

Head Travel Medicine Program

UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

Ana Sandino

Profesor Titular

Biología

Universidad de Santiago de Chile

Santiago, Chile

Roberto Riquelme

Académico Investigador

Universidad de Las Américas

Santiago, Chile

Juan Ugalde

Assistant Professor

Facultad de Ciencias de la Vida

Universidad Andrés Bello

Santiago, Chile

Mauricio Apablaza

Research Director

Gobierno

Universidad del Desarrollo

Santiago, Chile

Maria Olivares

Docente Investigador

Instituto de Ciencias e Innovación en Medicina

Universidad del Desarrollo

Santiago, Chile

fresia ferreccio

Full Professor, Director PhD Epidemiolgy Program

Public Health

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE FACULTAD DE MEDICINA, ESCUELA DE MEDICINA, DEPARTAMENTO DE SALUD PÚBLICA.

Santiago, Chile

SANDRA CORTES

ASSOCIATED PROFESSOR

PUBLIC HEALTH

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Pamela Rojas

Médico

Microbiología

Hospital Padre Hurtado

Santiago, Chile

Lorena Porte

Jefe Sección Microbiología

Laboratorio Clínico

Clínica Alemana

Santiago, Chile

Paola Campodonico

Director of Centro de Química Médica and Associate Professor

CENTRE OF MEDICINAL CHEMISTRY, FACULTY OF MEDICINE, UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

Jaime Cabrera

Assistant Professor

Chemistry

Universidad del Bio Bio

Concepcion, Chile

cristian calderon

inestigador/profesor

Centro de Química Medica

Universidad del Desarollo

Santiago, Chile

Aiko Adell

Profesor Asociado

Universidad Andrés Bello

Santiago, Chile

pamela araya

JEFE DE SECCIÓN

BIOMEDICO

INSTITUTO DE SALUD PUBLICA DE CHILE

SANTIAGO, Chile

Juan Hormazabal

Jefe

Departamento Biomédico

Public Health Institute of Chile

Santiago, Chile

Mauricio Canals

PROFESOR TITULAR

MEDICINA

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA

SANTIAGO, Chile

Daniel Ibáñez

Profesional

Laboratorio Biomédico

Instituto de Salud Pública de Chile

Santiago, Chile

Jose Manuel Munita Sepulveda

Líneas de Investigación

Educación

Medico Cirujano, UNIVERSIDAD DE LOS ANDES. Chile, 2004

Infectious Diseases, University of Texas Health Science Center at Houston. Estados Unidos, 2014

Internal Medicine, Facultad de Medicina Clinica Alemana - Universidad del Desarrollo. Chile, 2007

Physician, UNIVERSIDAD DE LOS ANDES. Chile

Experiencia Académica

Docente Part Time

Profesor Asociado Part Time

Profesor Asistente Adjunto Part Time

Experiencia Profesional

Medico Internista Full Time

Staff, Unidad de Paciente Critico Part Time

Premios y Distinciones

ASM Infectious Disease Fellow Travel Grant

ASM ICAAC Infectious Diseases Fellows Grant Program

IDWeek Trainee Travel Grant

Scholarship for Clinical and Research Training

Scholarship for Medical Subspecialties Abroad

Fellow

Article (65)

Abstract (1)

BookSection (4)

CaseReport (1)

EditorialMaterial (2)

Errata (1)

Proyecto (6)

Collaborative Effort to Study Multidrug-Resistant Gram-Negatives in Chile

Phylogenomic Analysis of the Chilean-Cordobes MRSA Clone and the Role of Heavy Metal Resistance in its Ability to Prevail in Chile

Genomic Characteristics of VRE Bloodstream Infections in Patients with Hematological Malignancies in Six Geographical Locations

Prospective Evaluation of Clinical Outcomes of Cancer Patients with Vancomycin-Resistant E. faecium Bacteremia

Review (3)