Man

Maria Elena Lienqueo Contreras

ASSOCIATE PROFESSOR

UNIVERSIDAD DE CHILE

Santiago, Chile

Líneas de Investigación


Biofuel-Bioethanol production; Biomolecule Separations and Purification; Modelling of Chromatographic Processe; Protein engineering of relevant enzymes in biotechnology; Enzymes for cellulose hydrolysis; Optimization of operational conditions for protein separation by chromatography

Educación

  •  CHEMICAL ENGINEER, UNIVERSIDAD DE CHILE. Chile, 1992
  •  CHEMICAL ENGINEERING, UNIVERSIDAD DE CHILE. Chile, 1992
  •  CHEMICAL ENGINEERING, UNIVERSIDAD DE CHILE. Chile, 1999

Experiencia Académica

  •   ASSITANT PROFESSOR Full Time

    UNIVERSIDAD DE CHILE

    PHYSICAL AND MATHEMATICAL SCIENCES

    SANTIAGO, Chile

    2000 - 2006

  •   ASSOCIATE PROFESSOR Full Time

    UNIVERSIDAD DE CHILE

    PHYSICAL AND MATHEMATICAL SCIENCES

    SANTIAGO, Chile

    2006 - 2019

  •   PROFESSOR Full Time

    UNIVERSIDAD DE CHILE

    PHYSICAL AND MATHEMATICAL SCIENCE

    SANTIAGO, Chile

    2019 - A la fecha

Experiencia Profesional

  •   Associate Professor Full Time

    Universidad de Chile

    Santiago, Chile

    1992 - A la fecha

Formación de Capital Humano


In the past 3 years the thesis directed are:
4 Master; Harris Ricardo (2012); Quiroga Ana Luz (2012); Ricardo Pezoa (2010); Victoria Cortínez (2010)
15 Undergraduate: Cortes, Trinidad (2013), Molina Javier (2013), Zuñiga, Felipe (2013), Martinez, Loreto (2012), De la Fuente Diego (2012); Becerra Pablo (2012) Briones Gonzalo (2012); Leonardo Stari (2012); Christian Wilken (2012); Sebastian Juri, (2011); Diaz Diego (2011); Roberto Stomayor (2010); Diego Schneuer (2010); Tomas Niklitschek (2010) y Quiroga Ana (2010)

2 Postdoctorate: Cristina Ravanal, Javier Gimpel
1 PhD Theses: Leyton, Allison
2 Undergraduate : Cortes, Ivan, Consuegra Veronica.

Current students:and postdoctorate
1 Postdoctorate: Stephanie Brain, Victor Corro
1 PhD Theses: Catalina Landeta
2 Undergraduate : Yasser Uarac, Sebastian Correa


Difusión y Transferencia


Presentation in several workshops and conferences in Chile and oversea.


Premios y Distinciones

  •   Roberto Ovalle Aguirre

    INSTITUTO DE INGENIEROS DE CHILE

    Chile, 1993

    The Prize "Roberto Ovalle Aguirre" has been awarded since 1949 to students graduating from engineering schools of the University of Chile, P. U. Católica de Chile, U. Concepcion, U.T.F. Holy Mary, U. Santiago de Chile, U. Diego Portales and U. Catolica de Valparaiso, authors of the best final projects related degree or installation or operation of an industry relevant to the promotion of the national economy.

  •   Prize Colegio de Ingenieros de Chile

    COLEGIO DE INGENIEROS DE CHILE A.G.

    Chile, 1993

    Each year the Colegio de Ingenieros provides a Distinction to engineers holding of the last class of Universities and Polytechnic Schools recognized by the Colegio de Ingenieros. This distinction is awarded to those engineers designating the respective universities, in recognition of academic achievement and their leadership and participation


 

Article (37)

Macrocystis pyrifera source of nutrients for the production of carotenoids by a marine yeast Rhodotorula mucilaginosa
Saccharification of Brown Macroalgae Using an Arsenal of Recombinant Alginate Lyases: Potential Application in the Biorefinery Process
Simulation of mono-PEGylated lysozyme separation in heparin affinity chromatography using a general rate model
The effect of a lytic polysaccharide monooxygenase and a xylanase from Gloeophyllum trabeum on the enzymatic hydrolysis of lignocellulosic residues using a commercial cellulase
Aqueous extraction of the sulfated polysaccharide ulvan from the green alga Ulva rigida – Kinetics and modeling.
Improvement in carbohydrate and phlorotannin extraction from Macrocystis pyrifera using carbohydrate active enzyme from marine Alternaria sp as pretreatment
Interaction between trypsin and alginate=> an ITC and DLS approach to the formation of insoluble complexes
Purification of phlorotannins from Macrocystis pyrifera using macroporous resins
The role of alginate lyases in the enzymatic saccharification of brown macroalgae, Macrocystis pyrifera and Saccharina latissima
Comparison of different types of pretreatment and enzymatic saccharification of Macrocystis pyrifera for the production of biofuel
Comparison of different types of pretreatment and enzymatic saccharification of Macrocystis pyrifera for the production of biofuel
High pressure homogenization of Nannochloropsis oculata for the extraction of intracellular components: Effect of process conditions and culture age
Identification and efficient extraction method of phlorotannins from the brown seaweed Macrocystis pyrifera using an orthogonal experimental design
Second generation bioethanol from Eucalyptus globulus Labill and Nothofagus pumilio: ionic liquid pretreatment boosts the yields
Second generation bioethanol from Eucalyptus globulus Labill and Nothofagus pumilio=> Ionic liquid pretreatment boosts the yields
Deconstruction of the green alga Ulva rigida in ionic liquids: closing the mass balance
Deconstruction of the green alga Ulva rigida in ionic liquids=> Closing the mass balance
Hydrophobic interaction chromatography for purification of monoPEGylated RNase A
Purification of transthyretin as nutritional biomarker of selenium status
A Practical Culture Technique for Enhanced Production of Manganese Peroxidase by Anthracophyllum discolor Sp4
Cloning of novel cellulases from cellulolytic fungi: Heterologous expression of a family 5 glycoside hydrolase from Trametes versicolor in Pichia pastoris
The current status of liquid biofuels in Chile
Experimental Validation of the Predictions of a Mathematical Model for Protein Purification and Tag Selection
USE OF IONIC LIQUIDS IN THE PRETREATMENT OF FOREST AND AGRICULTURAL RESIDUES FOR THE PRODUCTION OF BIOETHANOL
Bioenergy II: Biological Pretreatment with Fungi as a Tool for Improvement of the Enzymatic Saccharification of Eucalyptus globulus Labill to Obtain Bioethanol
Computer-aided design to select optimal polypeptide tags to assist the purification of recombinant proteins
Influence of tryptophan tags on the purification of cutinase, secreted by a recombinant Saccharomyces cerevisiae, using cationic expanded bed adsorption and hydrophobic interaction chromatography
Optimal opcration conditions for protein separation in hydrophobic interaction chromatography
Prediction of retention time of cutinases tagged with hydrophobic peptides in hydrophobic interaction chromatography
New approaches for predicting protein retention time in hydrophobic interaction chromatography
MINLP models for the synthesis of optimal peptide tags and downstream protein processing
Effect of surface hydrophobicity distribution on retention of ribonucleases in hydrophobic interaction chromatography
Optimal synthesis of multistep protein purification processes
Optimal synthesis of protein purification processes
Overproduction, purification, and characterization of beta-1,3-glucanase type II in Escherichia coli
Use of expert systems for the synthesis of downstream protein processes
An expert system for the selection and synthesis of multistep protein separation processes

BookSection (1)

Cap 6: Reformulation of Preserved Fish Products

BookWhole (1)

Production of bioethanol from brown algae

ConferencePaper (3)

Ionic liquid fractionation of woody biomass for fermentable monosaccharides
An Expert System for selection of protein purification processes: Experimental validation
Implementation in an expert system of a selection rationale for purification processes for recombinant proteins

Proyecto (12)

Development of a novel method for utilizing waste algal biomass to grow methionine-enriched Trichoderma reesei as high-value protein for feeds
Apoyo a la Formación de Redes Internacionales entre Centros de Investigación. CONICYT-REDES150014, Algal Biorefinery Netwook=> Foods of Norway-ICDB of Chile.
Incorporación de un Cromatógrafo líquido preparativo para fortalecer una plataforma orientada a la purificación de proteínas y bioproductos
CENTRO DE BIOTECNOLOGIA Y BIOINGENIERÍA.Comisión Nacional de lnvestigación Cientifica y Técnológica CONICYT.
Optimization of production of biofuels from macro-algae
Desarrollo de métodos de purificación de enzimas que combinan la precipitación de afinidad con polímeros de cadena flexible cargados con la cromatografía de interacción hidrofóbica (HIC)
Estudio de docking molecular en proteínas pegiladas para el análisis de su comportamiento en cromatografía de intercambio iónico (IEX) e interacción hidrofóbica (HIC).
Improvement of the lignocellulose hydrolysis by use of auxiliary enzymes
Apoyo a la Formación de Redes Internacionales entre Centros de Investigación” Bioproducts Discovery & Development Centre (BDDC) Universidad de Guelph-Biocomsa-U.de Chile. Conicyt VI-2010 065
Optimal treatment processes of lignocelluloses for bioethanol – consortium=> OPBIO, CONICYT-AKA.
Fondef “Investigación, desarrollo y producción de proteasas criofílicas comerciales y lipasas de origen antártico”.
Study of the effect of surface hydrophobicity amino acidic distribution on protein chromatographic behavior.

Review (4)

Mathematical Modeling of Protein Chromatograms
Methods of calculating protein hydrophobicity and their application in developing correlations to predict hydrophobic interaction chromatography retention
Current insights on protein behaviour in hydrophobic interaction chromatography
Predicting protein retention time in hydrophobic interaction chromatography
39
Maria Lienqueo

ASSOCIATE PROFESSOR

OF CHEMICAL AND BIOTECHNOLOGY ENGINEERING

UNIVERSIDAD DE CHILE

Santiago, Chile

16
Maria Salazar

Profesora Asociada

UNIVERSIDAD DE CHILE, FAC. DE CIENCIAS FÍSICAS Y MATEMATICAS DEPTO. INGENIERÍA QUÍMICA

Santiago, Chile

15
Juan Asenjo

Professor

CHEMICAL AND BIOTECHNOLOGY ENGINEERING

University of Chile

SANTIAGO, Chile

8
ANDREA MAHN

Profesor Titular

Ingeniería Química

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

4
René Carmona

PROFESOR ADJUNTO

INGENIERIA EN MADERAS Y SUS BIOMATERIALES

UNIVERSIDAD DE CHILE FACULTAD DE CIENCIAS FORESTALES Y DE LA CONSERVACIÓN DE LA NATURALEZA

Santiago, Chile

4
Carolina Shene

TITULAR PROFESSOR

CHEMICAL ENGINEERING

UNIVERSIDAD DE LA FRONTERA

TEMUCO, Chile

3
José Salgado

Associate Professor

Chemical Engineering, Biotechnology and Materials

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Tomas Perez-Acle

Full Professor

Computational Biology Lab

Fundación Ciencia para la Vida

Santiago, Chile

2
Alvaro Olivera

Principal Investigator and Assistant Professor

Chemical Engineering and Biotechnology

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Allison Leyton

Postdoctorado

Ingeniería

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

2
Francisca Acevedo

Académico asociado

Ciencias Básicas

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

1
Ana Quiroga

Associate researcher

Chemical Engineering

Imperial College London

London, Reino Unido

1
María Ravanal

Académico

Universidad Austral de Chile

Valdivia, Chile

1
Gonzalo Tortella

PROFESOR EN PRACTICA ASOCIADO A

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

1
Olga Rubilar

Profesor Asociado

Departamento de Ingeniería Química

UNIVERSIDAD DE LA FRONTERA

TEMUCO, Chile

1
Pablo Moisset de Espanés

Investigador asociado

FCFM

CeBiB, Universidad de Chile

Santiago, Chile

1
Barbara Andrews

FULL PROFESSOR

CHEMICAL ENGINEERING AND BIOTECHNOLOGY

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Alejandro Buschmann

FULL PROFESSOR

UNIVERSIDAD DE LOS LAGOS

PUERTO MONTT, Chile

1
Ivan Rapaport

Associate Professor

Mathematical Engineering

Universidad de Chile

Santiago, Chile

1
Gonzalo Tortella

Investigador responsable de proyectos Fondecyt de postdoctorado e iniciacion a la investigacion. Co-investigador de Proyectos Fondef

Universidad de La Frontera

Temuco, Chile

1
Carolina Camus

Investigador

Centro i-mar

Universidad de Los Lagos

Puerto Montt, Chile