Man

Jaime Andrés Rivas Pardo

Profesor Asociado

Universidad Mayor

Santiago, Chile

Líneas de Investigación


Mechanobiology of bacterial adhesion Physiology and mechanics of sarcomeric proteins Mechanobiochemistry at the single molecule level Protein structure, relation between structure and function

Educación

  •  Molecular Biology-Structural Biology-, UNIVERSIDAD DE CHILE. Chile, 2012
  •  Biochemistry-Enzimology, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2005
  •  Biochemist, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 2004

Experiencia Académica

  •   Postdoctoral Researcher Full Time

    COLUMBIA UNIVERSITY

    New York, Estados Unidos

    2012 - 2017

  •   Associate Research Scientiest Full Time

    COLUMBIA UNIVERSITY

    New York, Estados Unidos

    2017 - 2018

  •   Investigador Asociado Full Time

    UNIVERSIDAD DE SANTIAGO DE CHILE

    Santiago, Chile

    2018 - 2019

  •   Profesor Asistente Full Time

    Universidad Mayor

    Santiago, Chile

    2019 - 2023

  •   Profesor Asociado Full Time

    UNIVERSIDAD MAYOR

    Chile

    2023 - A la fecha

Experiencia Profesional

  •   Technician Full Time

    Universidad de Santiago de Chile

    Santiago, Chile

    2005 - 2007

Premios y Distinciones

  •   Mejor Trabajo de Incorporación 2018

    Sociedad Bioquímica y Biología Molecular

    Chile, 2018

    Mejor Trabajo Incorporación, reunión anual de la sociedad de Bioquímica y Biología Molecular 2018.

  •   Best Poster Presentation

    NEXOS USA Chile

    Estados Unidos, 2016

    Mejor presentación poster, reunión NEXOS US-Chile 2016 Philadelphia

  •   Best Presentation

    FASEB Science Research Conference

    Chile, 2016

    Mejor presentación, reunion FASEB Functional Disulfide Bonds in Health and Disease. Steamboat Springs, Colorado.


 

Article (25)

KLF17 is an important regulatory component of the transcriptomic response of Atlantic salmon macrophages to <i>Piscirickettsia salmonis</i> infection
Phylogenomic analysis of the <i>Porphyromonas gingivalis-Porphyromonas gulae</i> duo: approaches to the origin of periodontitis
Anaerobic RSH-dependent tellurite reduction contributes to Escherichia coli tolerance against tellurite
A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues
Non-Specific Antibodies Induce Lysosomal Activation in Atlantic Salmon Macrophages Infected by Piscirickettsia salmonis
Single-Nucleotide Polymorphisms (SNP) Mining and Their Effect on the Tridimensional Protein Structure Prediction in a Set of Immunity-Related Expressed Sequence Tags (EST) in Atlantic Salmon (Salmo salar)
Understanding gold toxicity in aerobically-grown Escherichia coli
The Mechanical Power of Titin Folding
Molecular strategy for blocking isopeptide bond formation in nascent pilin proteins
The power of the force: mechano-physiology of the giant titin
The Work of Titin Protein Folding as a Major Driver in Muscle Contraction
Mechanical Deformation Accelerates Protein Ageing
Multidomain proteins under force
Proteins Breaking Bad: A Free Energy Perspective
A HaloTag Anchored Ruler for Week-Long Studies of Protein Dynamics
Work Done by Titin Protein Folding Assists Muscle Contraction
Dissecting the functional roles of the conserved NXXE and HXE motifs of the ADP-dependent glucokinase from Thermococcus litoralis
Identifying Sequential Substrate Binding at the Single-Molecule Level by Enzyme Mechanical Stabilization
S-Glutathionylation of Cryptic Cysteines Enhances Titin Elasticity by Blocking Protein Folding
Crystal Structure, SAXS and Kinetic Mechanism of Hyperthermophilic ADP-Dependent Glucokinase from Thermococcus litoralis Reveal a Conserved Mechanism for Catalysis
Nanomechanics of HaloTag Tethers
Catalytic and regulatory roles of divalent metal cations on the phosphoryl-transfer mechanism of ADP-dependent sugar kinases from hyperthermophilic archaea
Direct observation of disulfide isomerization in a single protein
Divalent metal cation requirements of phosphofructokinase-2 from E. coli. Evidence for a high affinity binding site for Mn2+
Site-directed mutagenesis study of the microenvironment characteristics of Lys(213) of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase

BookSection (2)

Interfering with the Folding of Group A Streptococcal pili 2 Proteins
Real-time Detection of Thiol Chemistry in Single Proteins

Proyecto (12)

MechanoPhysiology of Titin
NANOMECHANICS OF BACTERIAL ADHESION
“Degradation of titin at the single molecular level”
High throughput single molecule AFM force-spectrometer
SINGLE MOLECULE STUDIES OF TITIN ELASTICITY
EVOLUTION OF RIBOKINASE SUPERFAMILY ENZYMES=> STRUCTURE-FUNCTION RELATIONSHIPS THAT DETERMINE SUBSTRATE SPECIFICITY, METAL ASSISTED MECHANISM AND PROTEIN STABILITY.
“Protein Domains Closure Triggered by Ligands and Transition State Analogs”
“Effect of Ligands in the Protein Domain Closure Studied by SAXS
FILOGENIA, MECANISMO CATALITICO Y ESPECIFICIDAD DE SUSTRATO EN ENZIMAS DE LA SUPERFAMILIA RIBOQUINASA. IMPLICACIONES PARA LA EVOLUCION DE LA SUPERFAMILIA.
FILOGENIA, MECANISMO CATALITICO Y ESPECIFICIDAD DE SUSTRATO EN ENZIMAS DE LA SUPERFAMILIA RIBOQUINASA. IMPLICACIONES PARA LA EVOLUCION DE LA SUPERFAMILIA.
ESTRUCTURA Y MECANISMO DE ACCION DE CARBOXIQUINASA FOSFOENOLPIRUVICA.
ESTRUCTURA Y MECANISMO DE ACCION DE CARBOXIQUINASA FOSFOENOLPIRUVICA.
27
Jaime Rivas

Profesor Asociado

Facultad de Ciencias

Universidad Mayor

Santiago, Chile

7
Victoria Guixé

Titular Profesor

Biology

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Eva Vallejos

Profesor Asociado

Facultad de Medicina Veterinaria y Agronomía

Universidad de Las Américas

Santiago, Chile

2
CESAR RAMIREZ

Assistant Professor

Institute for Biological and Medical Engineering

Pontificia Universidad Catolica de Chile

Santiago, Chile

2
Felipe Reyes

Assistant professor

Universidad de S

Santiago de Chile, Chile

2
Felipe Arenas

Profesor Asociado

Biología

UNIVERSIDAD SANTIAGO DE CHILE

Santiago, Chile

2
Ana Sandino

Profesor Titular

Biología

Universidad de Santiago de Chile

Santiago, Chile

1
Roberto Luraschi

Asistente de investigación

Departamento de biología

Universidad de Santiago de Chile

Santiago, Chile

1
Daniela Toro

Profesor Asistente

facultad de ciencias de la salud

Universidad Autonoma de Chile

Santiago, Chile

1
Alejandra Herrera

PROFESORA ASISTENTE

QUÍMICA Y FISICA

Universidad Autónoma de Chile

TALCA, Chile

1
Víctor Castro

Profesor Asistente

Departamento de Biología

UNIVERSIDAD DE CHILE

Ñuñoa, Chile

1
Carmen Imarai

Profesor Titular

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Claudia Muñoz

Investigador

Biología

Universidad de Santiago de Chile

Santiago, Chile

1
Juan Sandoval

Profesor Asistente

UNIVERSIDAD ARTURO PRAT

Iquique, Chile

1
Carlos Vera

Profesor Asociado

Departamento de Biología

Universidad de Santiago de Chile

Santiago, Chile

1
SEBASTIAN REYES

Profesor Asistente

Centro de Genómica y Bioinformática

Universidad Mayor de Chile

Santiago, Chile

1
Cristian Cortez

Profesor Asociado

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

1
Christian Wilson

Associate professor

Bioquimica y Biologia Molecular

Universidad de Chile

Santiago, Chile

1
Fernando Gonzalez

Titular Professor

Facultad de Ciencias de la Vida

Universidad Andres Bello

Santiago, Chile

1
Jorge Babul

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Elena Vidal

Directora Programas de Doctorado

Centro de Genomica y Bioinformatica

Universidad Mayor de Chile

Santiago, Chile

1
Alejandro Yévenes

Profesor Asistente

Química-Física

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile