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Juan Alejandro Godoy Zeballos

Tecnologo Medico

Laboratorio Clinico Cruz del Sur

Santiago, Chile

Neurociencias: Neurobiologia y señalización neuronal, estudio de la sinapsis neuronal

Tecnologo Medico, UNIVERSIDAD DE CHILE. Chile, 1981
Ciencias Biológicas- Microbiologia, UNIVERSIDAD DE CHILE. Chile, 1992
Biomedicina, UNIVERSITAT POMPEU FABRA. España, 2018

Investigador Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Ciencias Biológicas

santiago, Chile

1999 - 2019

Investigador CARE-Chile UC Full Time

Pontificia Univeversidad Católica de Chile

Santiago, Chile

1999 - 2019
Tecnologo Medico Full Time

Laboratorio Clinico Cruz del Sur

santiago, Chile

1990 - A la fecha


Mitostasis, Calcium and Free Radicals in Health, Aging and Neurodegeneration Godoy, Juan A.; Rios, Juvenal A.; Picon-Pages, Pol; Herrera-Fernandez, Victor; Swaby, Bronte; Crepin, Giulia; Vicente, Ruben; Fernandez-Fernandez, Jose M.; Munoz, Francisco J. Article ISI BIOMOLECULES (2021)
Morphological neurite changes induced by porcupine inhibition are rescued by Wnt ligands Godoy, Juan A.; Espinoza-Caicedo, Jasson; Inestrosa, Nibaldo C. Article ISI CELL COMMUNICATION AND SIGNALING (2021)
Oportunidad en la salud digital: una respuesta al control de las demencias Juan A. Godoy; Carola Ríos L.; Pía Venegas A.; Carolina López R.; José Luis Álvarez; Tomás P. Labbé; Camila Ramírez M.; Juvenal A. Ríos Article ISI SCIELO REVISTA MEDICA DE CHILE (2020)
Modulating Wnt signaling at the root: Porcupine and Wnt acylation Torres V.I.; Godoy, J.A.; Inestrosa, N. C. Article ISI SCOPUS PHARMACOLOGY THERAPEUTICS (2019)
Serine-Arginine Protein Kinase SRPK2 Modulates the Assembly of the Active Zone Scaffolding Protein CAST1/ERC2 Arancibia, Duxan; Lira, Matias; Cruz, Yocelin; Barrera, Daniela P.; Montenegro-Venegas, Carolina; Godoy, Juan A; Garner, Craig C.; Inestrosa, Nibaldo C.; Gundelfinger, Eckart D.; Zamorano, Pedro; Torres, Viviana I. Article ISI CELLS (2019)
Nicotine Modulates Mitochondrial Dynamics in Hippocampal Neurons Godoy, Juan A; Valdivieso, Angel G.; Inestrosa, Nibaldo C Article ISI SCOPUS Molecular Neurobiology (2018)
The Exocyst Component Exo70 Modulates Dendrite Arbor Formation, Synapse Density, and Spine Maturation in Primary Hippocampal Neurons Lira M.; Arancibia D.; Orrego P.R.; Montenegro-Venegas C.; Cruz Y.; GarcÃa J.; Leal-Ortiz S.; Godoy, J.A.; Gundelfinger E.D.; Inestrosa, N. C.; Garner C.C.; Zamorano P.; Torres V.I. Article ISI SCOPUS MOLECULAR NEUROBIOLOGY (2018)
Wnt3a ligand facilitates autophagy in hippocampal neurons by modulating a novel GSK-3 beta-AMPK axis Ríos, Juvenal A.; Godoy, Juan A; Inestrosa, Nibaldo C Article ISI SCOPUS CELL COMMUNICATION AND SIGNALING (2018)
Age Progression of Neuropathological Markers in the Brain of the Chilean Rodent Octodon degus, a Natural Model of Alzheimer's Disease Inestrosa, NC; Rios, JA; Cisternas P.; Tapia-Rojas, C; Rivera, DS; Braidy, N; Zolezzi, JM; Godoy JA; Carvajal, FJ; Ardiles AO; Bozinovic F.; Palacios, AG; Sachdev, PS Article ISI SCOPUS Brain Pathology (2015)
Multiple Cryptosporidium parvum subtypes detected in a unique isolate of a Chilean neonatal calf with diarrhea Mercado R.; Peña S.; Ozaki, LS.; Fredes, F; Godoy, J Article ISI SCOPUS Parasitology Research (2015)
The soluble extracellular fragment of neuroligin-1 targets A beta oligomers to the postsynaptic region of excitatory synapses Dinamarca, MC; Di Luca M.; Godoy JA; Inestrosa, NC Article ISI SCOPUS Biochemical and Biophysical Research Communications (2015)
Wnt5a inhibits K+ currents in hippocampal synapses through nitric oxide production Parodi, Jorge; Montecinos-Oliva, Carla; Varas, Rodrigo; Alfaro, Iván E.; Serrano, Felipe G.; Varas-Godoy, Manuel; Muñoz, Francisco J.; Cerpa, Waldo; Godoy, Juan A; Inestrosa, Nibaldo C Article ISI SCOPUS Molecular and Cellular Neuroscience (2015)
Phosphorylated tau potentiates A beta-induced mitochondrial damage in mature neurons Quintanilla, RA; von Bernhardi R.; Godoy JA; Inestrosa, NC; Johnson, GVW Article ISI SCOPUS NEUROBIOLOGY OF DISEASE (2014)
Role of Sirt1 During the Ageing Process: Relevance to Protection of Synapses in the Brain Godoy, J.A.; Zolezzi J.M.; Braidy, N; Inestrosa, N. C. Article ISI SCOPUS MOLECULAR NEUROBIOLOGY (2014)
Wnt-5 alpha increases NO and modulates NMDA receptor in rat hippocampal neurons Muñoz FJ.; Godoy JA; Cerpa, W.; Poblete IM; Huidobro-Toro, JP; Inestrosa, NC Article ISI BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Wnt-5a Ligand Modulates Mitochondrial Fission-Fusion in Rat Hippocampal Neurons Godoy, J.A.; Arrázola M.S.; Ordenes, D; Silva-Alvarez, C; Braidy, N; Inestrosa, N. C. Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
ATP Induces NO Production in Hippocampal Neurons by P2X(7) Receptor Activation Independent of Glutamate Signaling Codocedo, Juan Francisco; Godoy, Juan Alejandro; Poblete, Maria Ines; Inestrosa, Nibaldo C; HUIDOBRO-TORO, Juan Pablo; Mongin, Alexander A. Article ISI SCOPUS PLOS ONE (2013)
Canonical Wnt signaling protects hippocampal neurons from A beta oligomers: role of non-canonical Wnt-5a/Ca2+ in mitochondrial dynamics Silva-Alvarez, C; Arrazola, MS; Godoy JA; Ordenes, D; Inestrosa, NC Article ISI SCOPUS FRONTIERS IN CELLULAR NEUROSCIENCE (2013)
Nicotine Prevents Synaptic Impairment Induced by Amyloid-beta Oligomers Through alpha 7-Nicotinic Acetylcholine Receptor Activation Inestrosa, NC; Godoy JA; Vargas JY; Arrazola, MS; Rios, JA; Carvajal, FJ; Serrano, FG; Farias GG. Article ISI SCOPUS NEUROMOLECULAR MEDICINE (2013)
Peroxisome Proliferator-Activated Receptor (PPAR) gamma and PPAR alpha Agonists Modulate Mitochondrial Fusion-Fission Dynamics: Relevance to Reactive Oxygen Species (ROS)-Related Neurodegenerative Disorders? Zolezzi, Juan M.; Silva-Alvarez, Carmen; Ordenes, Daniela; Godoy, Juan A; Carvajal, Francisco J.; Santos, Manuel J.; Inestrosa, Nibaldo C; Ferreira, Sergio T. Article ISI SCOPUS PLOS ONE (2013)
Tetrahydrohyperforin Decreases Cholinergic Markers associated with Amyloid-beta Plaques, 4-Hydroxynonenal Formation, and Caspase-3 Activation in A beta PP/PS1 Mice Carvajal, FJ; Zolezzi, JM; Tapia-Rojas, C; Godoy JA; Inestrosa, NC Article ISI SCOPUS Journal of Alzheimer's Disease (2013)
Tetrahydrohyperforin Induces Mitochondrial Dynamics and Prevents Mitochondrial Ca2+ Overload after A beta and A beta-AChE Complex Challenge in Rat Hippocampal Neurons Zolezzi, JM; Carvajal, FJ; Rios, JA; Ordenes, D; Silva-Alvarez, C; Godoy JA; Inestrosa, NC Article ISI SCOPUS Journal of Alzheimer's Disease (2013)
Thiazolidinediones Promote Axonal Growth through the Activation of the JNK Pathway Quintanilla, Rodrigo A.; Godoy, Juan A; Alfaro, Ivan; Cabezas, Deny; Bernhardi, Rommy von; Bronfman, Miguel; Inestrosa, Nibaldo C; Allinquant, Bernadette Article ISI SCOPUS PLOS ONE (2013)
SIRT1 Regulates Dendritic Development in Hippocampal Neurons Codocedo, Juan F.; Allard, Claudio; Godoy, Juan A; Varela-Nallar, Lorena; Inestrosa, Nibaldo C; Allinquant, Bernadette Article ISI SCOPUS PLOS ONE (2012)
Amyloid-beta Peptide Fibrils Induce Nitro-Oxidative Stress in Neuronal Cells ILL-Raga G.; Ramos-Fernandez, E; Guix FX; Tajes M.; Bosch-Morato M.; Palomer E.; Godoy, J; Belmar S; Cerpa, W.; Simpkins, JW; Inestrosa, NC; Munoza, FJ Article ISI SCOPUS Journal of Alzheimer's Disease (2010)
Amyloid-beta-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the A beta peptide. Implications for the pathogenesis of Alzheimer's disease Dinamarca, MC; Sagal, JP; Quintanilla, RA; Godoy JA; Arrazola, MS; Inestrosa, NC Article ISI SCOPUS Molecular Neurodegeneration (2010)
Wnt-5a Modulates Recycling of Functional GABA(A) Receptors on Hippocampal Neurons Cuitino, L; Godoy JA; Farias GG.; couve, a; Bonansco, C.; Fuenzalida, M; Inestrosa, NC Article ISI SCOPUS Journal of Neuroscience (2010)
Wnt-5a occludes A beta oligomer-induced depression of glutamatergic transmission in hippocampal neurons Cerpa, W.; Farias GG.; Godoy JA; Fuenzalida, M; Bonansco, C.; Inestrosa, NC Article ISI SCOPUS Molecular Neurodegeneration (2010)
Wnt-5a/JNK Signaling Promotes the Clustering of PSD-95 in Hippocampal Neurons Farias GG.; alfaro ie; Cerpa, W.; Grabowski CP; Godoy JA; Bonansco, C.; Inestrosa, NC Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Wnt-7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons Cerpa, W.; Godoy JA; Alfaro I.; Farlas, GG; Metcalfe MJ; Fuentealba, R; Bonansco, C.; Inestrosa, NC Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Wnt-7a induces presynaptic colocalization of alpha 7-nicotinic acetylcholine receptors and adenomatous polyposis coli in hippocampal neurons Farias GG.; Valles, AS; Colombres M.; Godoy JA; Toledo EM; Lukas, RJ; Barrantes, FJ; Inestrosa, NC Article ISI SCOPUS JOURNAL OF NEUROSCIENCE (2007)
Peroxisomal proliferation protects from beta-amyloid neurodegeneration Santos MJ; Quintanilla, RA; Toro, AS; Grandy, R; Dinamarca, MC; Godoy JA; Inestrosa, NC Article ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Peroxisome proliferator-activated receptor gamma is expressed in hippocampal neurons and its activation prevents beta-amyloid neurodegeneration: role of Wnt signaling Inestrosa, NC; Godoy JA; Quintanilla, RA; Koenig, CS; Bronfman, M Article ISI SCOPUS EXPERIMENTAL CELL RESEARCH (2005)
The anti-inflammatory and cholinesterase inhibitor bifunctional compound IBU-PO protects from beta-amyloid neurotoxicity by acting on Wnt signaling components Farias GG.; Godoy JA; Vázquez MC; Adani, R; Meshulam, H; Avila J.; Amitai, G; Inestrosa, NC Article ISI SCOPUS NEUROBIOLOGY OF DISEASE (2005)
M1 muscarinic receptor activation protects neurons from beta-amyloid toxicity. A role for Wnt signaling pathway Farias GG.; Godoy JA; Hernández F.; Avila J.; Fisher, A; Inestrosa, NC Article ISI NEUROBIOLOGY OF DISEASE (2004)
Wnt-3a overcomes ?-amyloid toxicity in rat hippocampal neurons Alvarez, A.R.; Godoy, J.A.; Mullendorff, K; Olivares G.H.; Bronfman, M; Inestrosa, N. C. Article SCOPUS EXPERIMENTAL CELL RESEARCH (2004)
Wnt-3a overcomes beta-amyloid toxicity in rat hippocampal neurons Alvarez, AR; Godoy JA; Mullendorff, K; Olivares, GH; Bronfman, M; Inestrosa, NC Article ISI EXPERIMENTAL CELL RESEARCH (2004)
Activation of Wnt signaling and behavioral impairments rescues neurodegeneration induced by beta-amyloid fibrils De Ferrari, GV; Chacón MA; Barría MI; garrido, JL; Godoy JA; Olivares, G; Reyes, AE; Alvarez A.; Bronfman, M; Inestrosa, NC Article ISI SCOPUS MOLECULAR PSYCHIATRY (2003)
Protein kinase C inhibits amyloid beta-peptide neurotoxicity by acting on members of the Wnt pathway garrido, JL; Godoy, J; Alvarez A.; Bronfman, M; Inestrosa, NC Article ISI FASEB JOURNAL (2002)
Acetylcholinesterase-amyloid-?-peptide interaction and Wnt signaling involvement in A? neurotoxicity Inestrosa, N. C.; Alvarez A.; Godoy, J; Reyes A.; De Ferrari G.V. Article SCOPUS Acta Neurologica Scandinavica, Supplement (2000)
Acetylcholinesterase-amyloid-beta-peptide interaction and Wnt signaling involvement in A beta neurotoxicity Inestrosa, NC; Alvarez A.; Godoy, J; Reyes A.; De Ferrari, GV Article ISI ACTA NEUROLOGICA SCANDINAVICA (2000)


Role of hippocampal P2X7 receptors in the release of NO by ATP and related nucleotides Wilson, IMP; Godoy, J; Inestrosa, N; Huidobro-Toro, JP Abstract ISI PURINERGIC SIGNALLING (2010)
Peroxisomal proliferation prevents beta-amyloid-neurotoxicity in rat hippocampal neurons Quintanilla, RA; Godoy JA; Toro, A.; Santos MJ; Inestrosa, NC Abstract ISI JOURNAL OF NEUROCHEMISTRY (2005)


Peroxisomal proliferation prevents beta-amyloid neurodegeneration Santos MJ; Quintanilla, RA; Godoy JA; Toro, A.; Inestrosa, NC ConferencePaper ISI New Trends in Alzheimer and Parkinson Related Disorders: ADPD 2005 (2005)


Are microRNAs the Molecular Link Between Metabolic Syndrome and Alzheimer’s Disease? Codocedo J.F.; Ríos J.A.; Godoy, J.A.; Inestrosa, N. C. Review ISI SCOPUS (2016)
Signaling pathway cross talk in Alzheimer's disease Godoy JA; Rios, JA; Zolezzi, JM; Braidy, N; Inestrosa, NC Review ISI SCOPUS CELL COMMUNICATION AND SIGNALING (2014)
Wnt Signaling Modulates Pre- and Postsynaptic Maturation: Therapeutic Considerations Farias GG.; Godoy JA; Cerpa, W.; Varela-Nallar, L; Inestrosa, NC Review ISI SCOPUS Developmental Dynamics (2010)
Trolox and 17 beta-estradiol protect against amyloid beta-peptide neurotoxicity by a mechanism that involves modulation of the Wnt signaling pathway Quintanilla, RA; Muñoz FJ.; Metcalfe MJ; Hitschfeld, M; Olivares, G; Godoy JA; Inestrosa, NC Review ISI SCOPUS JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Juan Godoy

Tecnologo Medico

Laboratorio Clinico Cruz del Sur

Santiago, Chile

Nibaldo Inestrosa

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Rodrigo Quintanilla

Associate professor

Universidad Autónoma de Chile

Santiago, Chile

JUVENAL RÍOS

Investigador

CR de Investigación y Desarrollo

Instituto Nacional del Cáncer (INCANCER)

Santiago, Chile

Waldo Cerpa

Profesor Asociado

Biología Celular y Molecular

Pontificia Universidad Catolica de Chile

Santiago, Chile

Juan Zolezzi

Associate Professor

School of Medicine

UNIVERSIDAD DE MAGALLANES

Punta Arenas, Chile

Marco Fuenzalida

Full Professor

Physiology

UNIVERSIDAD DE VALPARAÍSO

Valparaíso, Chile

Ivan Alfaro

Associate Professor, Director of Innovation and Technology Development

Faculty of Medicine

Universidad del Desarrollo

Santiago, Chile

DOMINGO BONANSCO

Profesor Titular

Instituto de Fisiologia

UNIVERSIDAD DE VALPARAISO, FACULTAD DE CIENCIAS

Valparaiso, Chile

Francisco Carvajal

asistente de investigacion

Universidad de Magallanes

punta arenas, Chile

Gonzalo Olivares

ASSISTANT PROFESSOR

NEUROCIENCIA

Universidad de Chile

SANTIAGO, Chile

Giancarlo De Ferrari

Full Professor

Biological Sciences

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Ariel Reyes

Director de Departamento

Ciencias Biológicas

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

PEDRO ZAMORANO

Profesor Asociado

Depto Biomédico

Universidad de Antofagasta

Antofagasta, Chile

Matías Lira

Postdoc

Universidad San Sebastián

Santiago, Chile

Andrés Couve

Profesor Titular

Neurociencia

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

Rommy von Bernhardi

Full Professor

Neurology

DEPT. NEUROLOGY, FAC. MEDICINE PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Jose Garrido

Investigador asesor, part time

Universidad San Sebastián

Puerto Montt, Chile

Sebastian Belmar

Lorena Varela

Assistant Professor

Biological Sciences

Universidad Andres Bello

Santiago, Chile

Duxan Arancibia

Investigador Posdoctoral

Biomédico

Universidad de Antofagasta

Antofagasta, Chile

Alvaro Ardiles

Assistant Professor

Medicine

Universidad de Valparaíso

Valparaiso, Chile

RUBEN MERCADO

Academico

Pediatria y Cirugia Infantil Occidente

UNIVERSIDAD DE CHILE. FACULTAD DE MEDICINA. UNIDAD DOCENTE DE PARASITOLOGÍA.

Santiago, Chile

Jorge Parodi

Director de laboratorio

Universidad Mayor de Chile

Temuco, Chile

Rodrigo Varas

Profesor Asociado

Universidad Autónoma de Chile

Talca, Chile

Maria Barria

Investigador, Associate Professor

Universidad San Sebastián

Puerto Montt, Chile

Felix Diaz

Pedro Cisternas

Investigador Asociado

Biología Celular

Pontificia Universidad Católica de Chile

Santiago, Chile

Rodrigo Fuentealba

Postdoctoral Research Associate

Departamento de Inmunología Clínica y Reumatología / Facultad de Medicina

Pontificia Universidad Católica

Santiago, Chile

Claudio Allard

PROFESOR ASISTENTE

Química y Biología

Universidad de Atacama

Copiapó, Chile

Sebastian Peña

Instructor Adjunto

Pediatría y Cirugía Infantil Occidente

Universidad de Chile

Santiago, Chile

Marcelo Chacon

Postdoc

Neurology

UTHealth

Houston, Estados Unidos

Loreto Cuitiño

Investigador Asociado

Oftalmología

Hospital Clínico Universidad de Chile

229788866, Chile

MANUEL VARAS

Research Professor

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

Daniela Barrera

PhD Student

Environ SPA

Santiago, Chile

Juan Alejandro Godoy Zeballos

Líneas de Investigación

Educación

Tecnologo Medico, UNIVERSIDAD DE CHILE. Chile, 1981

Ciencias Biológicas- Microbiologia, UNIVERSIDAD DE CHILE. Chile, 1992

Biomedicina, UNIVERSITAT POMPEU FABRA. España, 2018

Experiencia Académica

Investigador Full Time

Experiencia Profesional

Investigador CARE-Chile UC Full Time

Tecnologo Medico Full Time

Article (41)

Abstract (2)

ConferencePaper (1)

Review (4)