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Cristian Fabián Paz Robles

Académico

Universidad de La Frontera

Temuco, Chile

Líneas de Investigación


Química Medicinal Química de Productos Naturales Síntesis y hemisintesis de compuestos bioactivos Análisis funcional de compuestos activos mediante biología molecular .

Educación

  •  Quimica, UNIVERSIDAD DE CONCEPCION. Chile, 2012
  •  Pedagogía en Química, UNIVERSIDAD DE CONCEPCION. Chile, 2007
  •  Quimico Analista, UNIVERSIDAD DE CONCEPCION. Chile, 2003

Experiencia Académica

  •   Académico Full Time

    UNIVERSIDAD DE LA FRONTERA

    Ingenieria y Ciencias

    Temuco, Chile

    2014 - A la fecha

  •   Académico Full Time

    UNIVERSIDAD DE LA FRONTERA

    Medicina

    Temuco, Chile

    2019 - A la fecha

Experiencia Profesional

  •   Operador Full Time

    UDT Unidad de Desarrollo Tecnológico UdeC

    Coronel, Chile

    2004 - 2004

Formación de Capital Humano


Tesis de Pregrado : 1



 

Article (39)

Antifungal Effects of Drimane Sesquiterpenoids Isolated from Drimys winteri against Gaeumannomyces graminis var. tritici
Drimenol, isodrimeninol and polygodial isolated from Drimys winteri reduce monocyte adhesion to stimulated human endothelial cells
Drimys winteri and isodrimeninol decreased foam cell formation in THP-1 derived macrophages
Maytenus disticha Extract and an Isolated β-Dihydroagarofuran Induce Mitochondrial Depolarization and Apoptosis in Human Cancer Cells by Increasing Mitochondrial Reactive Oxygen Species
Oxidation of Isodrimeninol with PCC Yields Drimane Derivatives with Activity against Candida Yeast by Inhibition of Lanosterol 14-Alpha Demethylase
PHYTOCHEMICAL AND CRYSTALLOGRAPHIC STUDIES OF Azara dentata EXTRACTS AND ITS CYTOTOXIC EFFECTS ON HUMAN BREAST CANCER CELL, MCF-7
ADSORPTION ABILITY OF ACTIVATED CARBON OBTAINED FROM SUB-BITUMINOUS COAL (LEBU, CHILE) TO CAPTURE TRIMETHYLAMINE
Alkaloids Purified from Aristotelia chilensis Inhibit the Human alpha 3 beta 4 Nicotinic Acetylcholine Receptor with Higher Potencies Compared with the Human alpha 3 beta 4 and alpha 7 Subtypes
Aristotelia chilensis (Mol.) Stuntz: A Natural Source of Bioactive Compounds
Aristoteline, an Indole-Alkaloid, Induces Relaxation by Activating Potassium Channels and Blocking Calcium Channels in Isolated Rat Aorta
Exposure to UV-B Radiation Leads to Increased Deposition of Cell Wall-Associated Xerocomic Acid in Cultures of Serpula himantioides
Occurrence of Soil Fungi in Antarctic Pristine Environments
8-Oxo-9-Dihydromakomakine Isolated from Aristotelia chilensis Induces Vasodilation in Rat Aorta: Role of the Extracellular Calcium Influx
Assessment of insecticidal responses of extracts and compounds of Drimys winteri, Lobelia tupa, Viola portalesia and Vestia foetida against the granary weevil Sitophilus granarius
Drimane Sesquiterpenoids Noncompetitively Inhibit Human alpha 4 beta 2 Nicotinic Acetylcholine Receptors with Higher Potency Compared to Human alpha 3 beta 4 and alpha 7 Subtypes
Three new dihydro-beta-agarofuran sesquiterpenes from the seeds of Maytenus boaria
TrypanocidalActivity of Natural Sesquiterpenoids Involves Mitochondrial Dysfunction, ROS Production and Autophagic Phenotype in Trypanosoma cruzi
A dihydro-beta-agarofuran sesquiterpene from Maytenus boaria
Antibiotic activity of Emerimicin IV isolated from Emericellopsis minima from Talcahuano Bay, Chile
Crystal structure of erioflorin isolated from Podanthus mitiqui (L.).
Effects of extracts from Maytenus on Aegorhinus superciliosus (Coleoptera: Curculionidae) and Hippodamia convergens (Coleoptera: Coccinellidae)
Inhibition on cholinesterase and tyrosinase by alkaloids and phenolics from Aristotelia chilensis leaves
(?)-8-oxohobartine a new ?ndole alkaloid from aristotelia chilensis (Mol.) Stuntz
(-)-8-oxohobartine a new indole alkaloid from Aristotelia chilensis (Mol.) Stuntz
(-)-Pentylsedinine, a New Alkaloid from the Leaves of Lobelia tupa with Agonist Activity at Nicotinic Acetylcholine Receptor
A monoclinic form of dendocarbin A: a borderline case of one-dimensional isostructural polymorphism
Hobartine: a tetracyclic indole alkaloid extracted from Aristotelia chilensis (maqui)
INHIBITION OF QUORUM SENSING BY DRIMANE LACTONES FROM CHILEAN FLORA
Two drimane lactones, valdiviolide and 11-epivaldiviolide, in the form of a 1:1 cocrystal obtained from Drimys winteri extracts
(E)-Ethyl 3-(3,4-dihydroxyphenyl)prop-2-enoate: a natural polymorph extracted from Aristotelia chilensis (Maqui)
A natural polymorph of Ethyl 3-(3,4-dihydroxyphenyl)-2-propenoate
A polymorphic form of 4,4-dimethyl-8-methylene-3-azabicyclo[3.3.1]non-2-en-2-yl 3-indolyl ketone, an indole alkaloid extracted from Aristotelia chilensis (maqui)
Drimendiol, A Drimane Sesquiterpene with Quorum Sensing Inhibition Activity
Synthesis of the ligand (z)-2-(3-methoxyphenylamino)-4-oxo-4-phenylbut-2- enoic acid and its antifungal activity against the wood stain fungi mucor plumbeus
SYNTHESIS AND AChE INHIBITING ACTIVITY OF 2, 4 SUBSTITUTED 6-PHENYL PYRIMIDINES
6,6,9a-Trimethyl-5,5a,6,7,8,9,9a,9b-octahydronaphtho[1,2-c]furan-1(3H)-one
Regio- and stereoselective Baeyer-Villiger oxidation on (R)-(+)-camphor adducts
Synthesis of a new nitrogenated drimane derivative with antifungal activity
X-RAY CRYSTALLOGRAPHIC STRUCTURAL STUDY ON A CINNAMOLIDE-CLASS SESQUITERPENE LACTONE FROM DRIMYS WINTERI FORST. VAR. CHILENSIS

BookSection (1)

Drimane sesquiterpenes from Drimys winteri.

ConferencePaper (1)

ACTIVIDAD INSECTICIDA DE ARISTOTELIA CHILENSIS SOBRE SITOPHILUS GRANARIUS (COLEOPTERA: CURCULIONIDAE).

Patent (3)

Método para combatir plagas de grano almacenado con extractos de Maytenus boaria
Sesquiterpenos de drimano con aplicación antifúngica.
“Extracto etanólico de hojas de Maytenus disticha como conantimicrobiano para el control de Pseudomonas aeruginosa, Staphylococcus aureus y Pseudomonas syringae”

Proyecto (10)

Indole Alkaloid sub products of Maqui processing as food additives to treatment of Alzheimer’s disease
Interdisciplinary network for study of Antarctic fungal bioactive compounds for control of cancer cells, pathogenic yeasts and bacterial strains to human health
Natural and hemisynthetic drimane sesquiterpenoids, inhibitors of nicotinic acetylcholine receptors. Looking for behavioral modulators.
Red de colaboración interdisciplinaria para la generación de medicamentos naturales desde la flora nativa Chilena
Desarrollo de estrategias de control contra Sitophilus granarius y Tribolium castaneum mediante el uso de compuestos naturales obtenidos de plantas vasculares endémicas
Red de colaboración interdisciplinaria para la generación de medicamentos naturales desde la flora nativa Chilena
“Purificación y determinación estructural de metabolitos secundarios de plantas nativas del valle de Trapa Trapa. Evaluación de potencial antibacteriano contra mastitis bovina”
MOLECULAR DETERMINATION OF NATURAL COMPOUNDS FROM NATIVE CHILEAN FLORA.
Síntesis y evaluación funcional de heterociclos derivados de Isoxazoles y Pirazoles 3-carboxamidas, con potencial actividad analgésica. Inhibición de canales de sodio Nav1.8
Discovery of novel antimicrobial targeting cell division
44
Cristian Paz

Académico

Ciencias Químicas

Universidad de La Frontera

Temuco, Chile

8
JOSE BECERRA

Professor

Botany Department

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

5
Viviana Burgos

Estudiante

Ciencias básicas

Universidad de La Frontera

Temuco, Chile

4
Mario Silva

Emeritus Professor

Botany Department

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

4
Claudia Perez

Academic

Botany

University of Concepción

Concepción, Chile

3
Paola Durán

Profesor Asociado

Vicerrectora Académica

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

2
Ivan Brito

Full Professor

Chemsitry

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

2
Adrian Paredes

Academico

Química

UNIVERSIDAD DE ANTOFAGASTA

Antofagasta, Chile

2
Ivan Brito

Profesor Titular

Quimica

Universidad de Antofagasta

Antofagasta, Chile

2
Patricio Barra

Profesor Asistente

Scientific and Technological Bioresource Nucleus

Universidad de La Frontera

Temuco, Chile

2
Jaime Cabrera

Assistant Professor

Chemistry

Universidad del Bio Bio

Concepcion, Chile

1
María Mora

Full Professor

Ciencias Químicas y Recursos Naturales

Universidad de La Frontera

TEMUCO, Chile

1
Paola Mendez

Investigadora

Química

Instituto de Transferencia Tecnológica y Emprendimiento LTDA

Concepción, Chile

1
Ignacio Jofré

Postdoctoral Researcher

Departamento de Ciencias Químicas

Universidad de La Frontera

Temuco, Chile

1
Milko Jorquera

PROFESOR TITULAR

CIENCIAS QUIMICA Y RECURSOS NATURALES

UNIVERSIDAD DE LA FRONTERA

TEMUCO, Chile

1
Cristian Balbontin

Investigador

Produccion Vegetal

Instituto de Investigaciones Agropecuarias

Chillán, Chile

1
Jorge Toledo

Director de Departamento

Fisiopatología

Universidad de Concepción

Concepcion, Chile

1
Clemente Palacios

Académico

Química y Farmacia

Universidad Arturo Prat

Iquique, Chile

1
Götz Palfner

Profesor Asociado

Botánica

Universidad de Concepción

Concepción, Chile

1
Homero Urrutia

Profesor titular

Facultad de Ciencias Biológicas

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

1
IVAN GONZALEZ

Profesor Asistente

Fisiopatología

Universidad De Concepcion

Concepción, Chile

1
Nery Jara

Profesor Asistente

Departamento de Farmacología

Universidad de Concepción

Concepción, Chile

1
Javiera Gavilán

Estudiante de Doctorado

Fisiología

Universidad de Concepción

Concepcion, Chile

1
Katherine Sossa

Associate professor

Centro de Biotecnología

Universidad de Concepción

Concepción, Chile

1
Solange Torres

Investigador Postdoctoral

Botánica

Universidad de Concepción

Concepción, Chile

1
margarita gutierrez

Proffesor

UNIVERSIDAD DE TALCA

Talca, Chile

1
CARLOS PEÑA

PROFESOR

INSTITUTO DE CIENCIAS QUIMICAS APLICADAS

Universidad Autónoma de Chile

TEMUCO, Chile