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Jose Suazo Sanhueza

Profesor Asociado

Facultad de Odontologia, Universidad de Chile

Santiago, Chile

Líneas de Investigación


Genética de malformaciones craneofaciales Genética de enfermedades metabólicas Genética del desarrollo craneofacial

Educación

  •  Tecnólogo Médico, UNIVERSIDAD DE CHILE. Chile, 2000
  •  Tecnología Médica, UNIVERSIDAD DE CHILE. Chile, 1999
  •  Doctor en Ciencias Biomédicas, UNIVERSIDAD DE CHILE. Chile, 2008

Experiencia Académica

  •   Profesor Asistente Full Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2007 - 2011

  •   Investigador Adjunto Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Santiago, Chile

    2011 - 2014

  •   Profesor Asociado Full Time

    UNIVERSIDAD DE CHILE

    Odontología

    Santiago, Chile

    2014 - A la fecha

Experiencia Profesional

  •   Tecnólogo Médico Part Time

    Banco de Sangre, Hospital San Jose

    Santiago, Chile

    2000 - 2002

Formación de Capital Humano


2013-2014 Rodrigo Herrera Reyes. “Enfermedades crónicas en personas de ascendencia amerindia de la Encuesta Nacional de Salud 2009. Tesis conducente al Grado de Magister en Epidemiología. Facultad de Medicina, Pontificia Universidad Católica de Chile.

2016 Cristian Ramírez Chau. "Estudio de asociación entre el polimorfismo c.667C>T del gen de la enzima 5,10-metilentetrahidrofolato reductasa y la fisura labiopalatina no sindrómica en Chile". Tesis conducente al Título de Cirujano Dentista, Facultad de Odontología, Universidad de Chile

2016 Natalia Millacura Valenzuela "Estudio piloto: Asociación entre niveles de metilación global de ADN y riesgo de presentar fisura labio palatina no sindrómica en una población chilena". Tesis conducente al Título de Cirujano Dentista, Facultad de Odontología, Universidad de Chile

2019-2020 Gabriela Caceres Rojas. "FISURAS OROFACIALES EN CHILE: ASOCIACIÓN ENTRE NIVELES DE METILACIÓN GLOBAL DEL ADN Y VARIANTES GENÉTICAS PRESENTES EN MTHFR, SLC19A1 Y TCN2. Tesis conducente al grado de Magister en Genética, Facultad de Medicina, Universidad de Chile.



 

Article (27)

A SHMT1 variant decreases the risk of nonsyndromic cleft lip with or without cleft palate in Chile

Salamanca, Carlos; Gonzalez-Hormazabal, Patricio; Recabarren, Andrea S.; Recabarren, Pamela A.; Pantoja, Roberto; Leiva, Noemi; Pardo, Rosa; Suazo, Jose

Article ISI SCOPUS
ORAL DISEASES  (2020)

Platelet Serotonin Levels Are Associated with Plasma Soluble Leptin Receptor Concentrations in Normoglycemic Women

Rodrigo Cataldo, Luis; Suazo, Jose; Olmos, Pablo; Bravo, Carolina; Galgani, Jose E.; Fex, Malin; Alfredo Martinez, J.; Santos, Jose L.

Article ISI SCOPUS
JOURNAL OF DIABETES RESEARCH  (2019)

Premature Vascular Aging in Guinea Pigs Affected by Fetal Growth Restriction

Paz, Adolfo A.; Arenas, German A.; Castillo-Galan, Sebastian; Penaloza, Estefania; Caceres-Rojas, Gabriela; Suazo, Jose; Herrera, Emilio A; Krause, Bernardo J.

Article ISI SCOPUS
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES  (2019)

Gene-gene interaction for nonsyndromic cleft lip with or without cleft palate in Chilean case-parent trios

Suazo, J; Santos, JL; Colombo, A; Pardo, R

Article ISI SCOPUS
ARCHIVES OF ORAL BIOLOGY  (2018)

Haplotype-based gene-gene interaction of bone morphogenetic protein 4 and interferon regulatory factor 6 in the etiology of non-syndromic cleft lip with or without cleft palate in a Chilean population

Blanco, R.; Colombo, A.; Pardo, A.; Suazo, J.

Article ISI SCOPUS
EUROPEAN JOURNAL OF ORAL SCIENCES  (2017)

Inhibition of the 3-Hydroxy-3-Methyl-Glutaryl-CoA Reductase Induces Orofacial Defects in Zebrafish

Signore, IA.; Jerez, C.; Figueroa, D.; Suazo. J.; Marcelain, K.; Cerda, O.; Colombo, A.

Article ISI SCOPUS
Birth Defects Research Part A - Clinical and Molecular Teratology  (2016)

Maternal biomarkers of methylation status and non-syndromic orofacial cleft risk: a meta-analysis

Blanco, R.; Colombo, A.; Pardo, A.; Suazo, J.

Article ISI SCOPUS
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY  (2016)

MTHFR c.677C > T is a risk factor for non-syndromic cleft lip with or without cleft palate in Chile

Ramirez-Chau, C.; Blanco, R.; Colombo, A.; Pardo, A.; Suazo, J.

Article ISI SCOPUS
ORAL DISEASES  (2016)

Fluoxetine Impairs Insulin Secretion without Modifying Extracellular Serotonin Levels in MIN6 beta-cells

Cataldo, LR; Cortes, VA; Mizgier, ML; Aranda, E; Mezzano D.; Olmos, P; Galgani, JE; Suazo, J; Santos, JL

Article ISI SCOPUS
Experimental and Clinical Endocrinology and Diabetes  (2015)

Maternal obesity is a risk factor for orofacial clefts: a meta-analysis

Blanco, R; Colombo, A; Suazo, J

Article ISI SCOPUS
British Journal of Oral and Maxillofacial Surgery  (2015)

Novel splice-affecting variants in CYP27A1 gene in two Chilean patients with Cerebrotendinous Xanthomatosis

Smalley SV; Preiss Y.; Suazo, J; Vega, JA; Angellotti, I; Lagos, CF; Rivera, E; Kleinsteuber, K; Campion, J.; Martinez, JA; Maiz A.; Santos, JL

Article ISI SCOPUS
Genetics and Molecular Biology  (2015)

Association between genetic polymorphisms of interleukin 6 (IL6), IL6R and IL18 with metabolic syndrome in obese Chilean children

Suazo, J; Smalley SV; Hodgson, MI; Weisstaub G.; González A; Santos, JL

Article ISI
REVISTA MEDICA DE CHILE  (2014)

GENETIC RISK SCORE FOR NONSYNDROMIC CLEFT LIP WITH OR WITHOUT CLEFT PALATE FOR A CHILEAN POPULATION

Blanco, R; Colombo, A; Suazo, J

Article ISI SCOPUS
GENETIC COUNSELING  (2014)

Methylenetetrahydrofolate reductase polymorphisms as risk factors for myelomeningocele

Pardo R.; Suazo, J; Castillo, S.; Vargas, M.; Zalavari, A; Santos, JL; Blanco, R; Rotter, K; Solar M.; Tapia, E

Article ISI
REVISTA MEDICA DE CHILE  (2014)

Daam1a mediates asymmetric habenular morphogenesis by regulating dendritic and axonal outgrowth

Colombo, A; Palma K.; Armijo, L; Mione, M; Signore, IA; Morales C. ; Guerrero, N; Meynard, MM; Perez, R; Suazo, J; Marcelain, K; Briones L.; Haartel, S; Wilson, SW; Concha, ML

Article ISI SCOPUS
Development (Cambridge)  (2013)

Family-Based Association Study Between SLC2A1, HK1, and LEPR Polymorphisms With Myelomeningocele in Chile

Suazo, J; Pardo R.; Castillo, S.; Martin, LM; Rojas F.; Santos, JL; Rotter, K; Solar M.; Tapia, E

Article ISI SCOPUS
Reproductive Sciences  (2013)

Prevalence of metabolic syndrome in obese Chilean children and association with gene variants of the leptin-melanocortin system

Suazo, J; Hodgson, MI; Obregon AM,; Valladares, M; Weisstaub G.; Amador, P; Santos, JL

Article ISI SCOPUS
Journal of Pediatric Endocrinology and Metabolism  (2013)

Risk variants in BMP4 promoters for nonsyndromic cleft lip/palate in a Chilean population

Suazo, J; Tapia, JC; Santos, JL; Castro, VG; Colombo, A; Blanco, R

Article ISI SCOPUS
BMC Medical Genetics  (2011)

Association Between Bone Morphogenetic Protein 4 Gene Polymorphisms with Nonsyndromic Cleft Lip with or without Cleft Palate in a Chilean Population

Suazo, J; Santos, JL; Jara, L; Blanco, R

Article ISI SCOPUS
DNA and Cell Biology  (2010)

Association Between TGFB3 and Nonsyndromic Cleft Lip With or Without Cleft Palate in a Chilean Population

Suazo, J; Santos, JL; Scapoli, L; Jara, L; Blanco, R

Article ISI SCOPUS
Cleft Palate-Craniofacial Journal  (2010)

Parent-of-Origin Effects for MSX1 in a Chilean Population With Nonsyndromic Cleft Lip/Palate

Suazo, J; Santos, JL; Jara, L; Blanco, R

Article ISI SCOPUS
American Journal of Medical Genetics, Part A  (2010)

Assessment of the association between SMAD1 and HHIP gene variation and non-syndromic cleft-lip palate in Chilean case-parent trios

Suazo, J; Santos, JL; Jara, L; Blanco, R

Article ISI SCOPUS
GENETICS AND MOLECULAR BIOLOGY  (2008)

No evidence for linkage and association between 4q Microsatellite markers and nonsyndromic cleft lip and palate in Chilean case-parents trios

Blanco, R; Suazo, J; Santos, JL; Carreno, H; Palomino, H; Jara, L

Article ISI SCOPUS
Cleft Palate-Craniofacial Journal  (2005)

Association between 10 microsatellite markers and nonsyndromic cleft lip palate in the Chilean population

Blanco, R; Suazo, J; Santos, JL; Paredes M.; Sung, H; Carreno, H; Jara, L

Article ISI SCOPUS
Cleft Palate-Craniofacial Journal  (2004)

Linkage disequilibrium between MSX1 and non-syndromic cleft lip/palate in the Chilean population

Suazo, J; Santos, JL; Carreno, H; Jara, L; Blanco, R

Article ISI SCOPUS
JOURNAL OF DENTAL RESEARCH  (2004)

Evidence for association between microsatellite markers located on 6p22-25 and nonsyndromic cleft lip palate using the case-parents trio design in the Chilean population

Blanco, R; Suazo, J; Santos, JL; Carreno, H; Paredes M.; Jara, L; Eltit F.

Article ISI
REVISTA MEDICA DE CHILE  (2003)

Association study of the nonsyndromic cleft lip/palate phenotype and microsatellite markers located in 6p, 17q and 19q

Carreno, H; Suazo, J; Paredes M.; Sola, J.; Valenzuela J.; Blanco, R

Article ISI
REVISTA MEDICA DE CHILE  (2002)

Abstract (2)

High prevalence of PNPLA3 rs738409 (I148M) polymorphism in Chilean latino population and its association to non-alcoholic fatty liver disease risk and histological disease severity

Arrese M.; Arab, JP; Riquelme A.; Benitez, CE; Barrera F.; Soza A.; Miquel, JF; Hernandez-Rocha, C; Suazo, J; Duarte, I; Robles C.; Sandoval, D; Santos, JL

Abstract ISI
HEPATOLOGY  (2015)

Linkage disequilibrium between nonsyndromic cleft lip/palate (NSCLP) and 5 STR loci located in 6p22-25 using the case-parent trio design

Blanco, R; Suazo, J; Santos, JL; Carreno, H; Sung, H; Eltit F.; Jara, L

Abstract
JOURNAL OF DENTAL RESEARCH  (2003)

Letter (1)

Linkage Disequilibrium Between IRF6 Variants and Nonsyndromic Cleft Lip/Palate in the Chilean Population

Suazo, J; Santos, JL; Jara, L; Blanco, R

Letter ISI
AMERICAN JOURNAL OF MEDICAL GENETICS PART A  (2008)

Review (1)

Risk of type 2 diabetes mellitus associated with statin therapy: evidence and possible mechanisms

Suazo, J; Rigotti, A.

Review ISI
REVISTA MEDICA DE CHILE  (2014)

31
Jose Suazo

Profesor Asociado

Instituto de Investigación en Ciencias Odontológicas

Facultad de Odontologia, Universidad de Chile

Santiago, Chile

29
José Suazo

Profesor Asociado

Instituto de Investigación en Ciencias Odontológicas

Universidad de Chile

Santiago, Chile

19
JOSE SANTOS

Full Professor

Department of Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

11
Lilian Jara

Titular Professor

Human Molecular Genetic

UNIVERSIDAD DE CHILE / FACULTAD DE MEDICINA

Santiago, Chile

9
Alicia Colombo

Profesora Asociada/Director Científico Biobanco de Tejidos y Fluidos de la Universidad de Chile

Departamento de Anatomía Patológica

Universidad de Chile

Santiago, Chile

2
JOSE GALGANI

ASSOCIATE PROFESSOR

NUTRITION, DIABETES AND METABOLISM; AND UDA-CIENCIAS DE LA SALUD, NUTRICION Y DIETETICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Katherine Marcelain

Profesora Asociada

Oncología Básico Clínica

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA

Santiago, Chile

2
Rosa Pardo

Profesora Asociada

Medicina

Hospital Clínico Universidad de Chile

Santiago, Chile

1
Ana Obregón

Docente Investigador

Facultad de Ciencias de la Salud

Universidad San Sebastian

Concepción , Chile

1
Pedro PANTOJA

Profesor Titular

Cirugía Maxilofacial

Universidad de Chile

Santiago, Chile

1
Emilio HERRERA

Full Professor

Faculty of Medicine, ICBM

Universidad de Chile

Santiago, Chile

1
María Mizgier

Postdoctorate

Universidad de Los Andes

Santiago, Chile

1
Arnoldo Riquelme

Director UDA Ciencias de la Salud (Carreras de Nutrición y dietética, Fonoaudiología y Kinesiología)

Gastroenterología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Karina Palma

Postdoctorado

Instituto de Neurociencia Biomédica BNI

Universidad de Chile

Santiago, Chile

1
Carlos Salamanca

ACADEMICO

Universidad de La Frontera

TEMUCO, Chile

1
Macarena Valladares

Profesor asociado

UNIVERSIDAD BERNARDO O'HIGGINS

Santiago, Chile

1
Juan Arab

Assistant Professor

Gastroenterologia

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Arnoldo Riquelme

Profesor titular

Gastroenterología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE GASTROENTEROLOGÍA

Santiago, Chile

1
MARCO ARRESE

FULL PROFESSOR

GASTROENTEROLOGY

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Bernardo Krause

Associate Professor

Insituto de Ciencias de la Salud

Universidad de O'Higgins

Rancagua, Chile

1
Eduardo Aranda

Biochemist

Hematology

P. UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Victor Cortes

Associate professor

Nutrition, Diabetes and Metabolism

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Attilio Rigotti

Full Professor

Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE - ESCUELA DE MEDICINA - DEPTO DE GASTROENTEROLOGÍA

Santiago, Chile

1
Patricio Gonzalez

Profesor Asociado

ICBM

UNIVERSIDAD DE CHILE

Santiago, Chile

1
JULIO TAPIA

Full Professor

Program of Cellular and Molecular Biology

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Francisco Barrera

Profesor Asociado

Gastroenterología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Lorena Armijo

Profesor asistent

Universidad San Se

Concepción, Chile

1
Sergio Weisstaub

INTA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Paola Amador

Fisiatra. Jefa de Servicio

de Medicina

Hospital Clínico Universidad de Chile

Santiago, Chile